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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P52907




SWISS-2DPAGE:  P52907


P52907


General information about the entry
View entry in simple text format
Entry nameCAZA1_HUMAN
Primary accession numberP52907
integrated into SWISS-2DPAGE on April 1, 2000 (release 12)
2D Annotations were last modified onMarch 31, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=F-actin-capping protein subunit alpha-1; AltName: Full=CapZ alpha-1;.
Gene nameName=CAPZA1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=20529951; PubMed=11079567; [NCBI, ExPASy, EBI, Israel, Japan]
Jung E., Hoogland C., Chiappe D., Sanchez J.-C., Hochstrasser D.F.
''''''The establishment of a human liver nuclei 2-DE reference map'';'';''
Electrophoresis 21(1):3483-3487(2000)
[2]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=5.40; Mw=32417  [identification data]
pI=5.38; Mw=32068  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [2].



NUCLEI_LIVER_HUMAN {Soluble nuclear proteins and matrix from liver tissue}
Homo sapiens (Human)
Tissue: Liver
NUCLEI_LIVER_HUMAN
  map experimental info
  protein estimated location
 
NUCLEI_LIVER_HUMAN

MAP LOCATIONS:
pI=5.49; Mw=32034  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWP52907.
REPRODUCTION-2DPAGEIPI00005969; IPI00005969.
REPRODUCTION-2DPAGEP52907; P52907.
Siena-2DPAGEP52907; CAZA1_HUMAN.
UniProtKB/Swiss-ProtP52907; CAZA1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCAZA1_HUMAN
Primary accession numberP52907
Secondary accession number(s) Q53FQ6 Q6FHD5
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on October 19, 2011 (version 116)
Name and origin of the protein
DescriptionRecName: Full=F-actin-capping protein subunit alpha-1; AltName: Full=CapZ alpha-1;
Gene nameName=CAPZA1
Encoded onName=CAPZA1
Keywords3D-structure; Acetylation; Actin capping; Actin-binding; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU56637; AAC00533.1; -; mRNA
EMBLCR407657; CAG28585.1; -; mRNA
EMBLCR541819; CAG46618.1; -; mRNA
EMBLBT019364; AAV38171.1; -; mRNA
EMBLAK223226; BAD96946.1; -; mRNA
EMBLAL603832; CAI14054.1; -; Genomic_DNA
EMBLAL929470; CAI14054.1; JOINED; Genomic_DNA
EMBLAL929470; CAI16528.1; -; Genomic_DNA
EMBLAL603832; CAI16528.1; JOINED; Genomic_DNA
EMBLBC000144; AAH00144.1; -; mRNA
IPIIPI00005969; -; .
PIRG02639; G02639; .
RefSeqNP_006126.1; NM_006135.2; .
UniGeneHs.727604; -; .
PDB1MQ1; NMR; -; C/D=265-276
PDB1MWN; NMR; -; X/Y=265-276
PDBsum1MQ1; -; .
PDBsum1MWN; -; .
ProteinModelPortalP52907; -; .
SMRP52907; 7-277; .
IntActP52907; 6; .
MINTMINT-5001076; -; .
STRINGP52907; -; .
PhosphoSiteP52907; -; .
SWISS-2DPAGEP52907; -; .
OGPP52907; -; .
REPRODUCTION-2DPAGEIPI00005969; -; .
REPRODUCTION-2DPAGEP52907; -; .
PeptideAtlasP52907; -; .
PRIDEP52907; -; .
EnsemblENST00000263168; ENSP00000263168; ENSG00000116489; .
GeneID829; -; .
KEGGhsa:829; -; .
UCSCuc001ecj.1; human; .
CTD829; -; .
GeneCardsGC01P111020; -; .
H-InvDBHIX0000892; -; .
HGNCHGNC:1488; CAPZA1; .
MIM601580; gene; .
neXtProtNX_P52907; -; .
PharmGKBPA26069; -; .
eggNOGprNOG10294; -; .
GeneTreeENSGT00390000006476; -; .
HOGENOMHBG397839; -; .
HOVERGENHBG050810; -; .
InParanoidP52907; -; .
OMAACDSALR; -; .
OrthoDBEOG45DWQ0; -; .
PhylomeDBP52907; -; .
ReactomeREACT_604; Hemostasis; .
ReactomeREACT_6900; Immune System; .
NextBio3414; -; .
ArrayExpressP52907; -; .
BgeeP52907; -; .
CleanExHS_CAPZA1; -; .
GenevestigatorP52907; -; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005576; C:extracellular region; TAS:Reactome; .
GOGO:0008290; C:F-actin capping protein complex; TAS:ProtInc; .
GOGO:0071203; C:WASH complex; IDA:UniProtKB; .
GOGO:0003779; F:actin binding; TAS:ProtInc; .
GOGO:0030036; P:actin cytoskeleton organization; IEA:InterPro; .
GOGO:0051693; P:actin filament capping; IEA:UniProtKB-KW; .
GOGO:0007596; P:blood coagulation; TAS:Reactome; .
GOGO:0006928; P:cellular component movement; TAS:UniProtKB; .
GOGO:0045087; P:innate immune response; TAS:Reactome; .
GOGO:0006461; P:protein complex assembly; TAS:ProtInc; .
InterProIPR017865; F-actin_cap_asu_CS; .
InterProIPR002189; WASH_F-actin_cap_alpha; .
PANTHERPTHR10653; F-actin_cap_A; 1; .
PfamPF01267; F-actin_cap_A; 1; .
PRINTSPR00191; FACTINCAPA; .
PROSITEPS00748; F_ACTIN_CAPPING_A_1; 1; .
PROSITEPS00749; F_ACTIN_CAPPING_A_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server