World-2DPAGE Home
Home  |  Contact

Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P63017




SWISS-2DPAGE:  P63017


P63017


General information about the entry
View entry in simple text format
Entry nameHSP7C_MOUSE
Primary accession numberP63017
Secondary accession number(s) P08109
integrated into SWISS-2DPAGE on June 30, 1999 (release 10)
2D Annotations were last modified onOctober 1, 2001 (version 3)
General Annotations were last modified on May 19, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=Heat shock cognate 71 kDa protein; AltName: Full=Heat shock 70 kDa protein 8;.
Gene nameName=Hspa8
Synonyms=Hsc70, Hsc73
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
MEDLINE=96154592; PubMed=8586073; [NCBI, ExPASy, EBI, Israel, Japan]
Anderson N.L., Esquer-Blasco R., Hoffmann J.-P., Meheus L., Raymackers J., Steiner S., Witzmann F., Anderson N.G.
''''''An updated two-dimensional gel database of rat liver proteins useful in gene regulation and drug effect studies'';'';''
Electrophoresis 16(1):1977-1981(1995)
[2]   MAPPING ON GEL
MEDLINE=93162044; PubMed=1286668; [NCBI, ExPASy, EBI, Israel, Japan]
Giometti C.S., Taylor J., Tollaksen S.L.
''''''Mouse liver protein database: a catalog of proteins detected by two- dimensional gel electrophoresis'';'';''
Electrophoresis 13(1):970-991(1992)
[3]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue
BAT_MOUSE
  map experimental info
  protein estimated location
 
BAT_MOUSE

MAP LOCATIONS:
pI=4.99; Mw=38586  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [3].



LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=5.25; Mw=67781
pI=5.28; Mw=67421  [identification data]
pI=5.30; Mw=67063  [identification data]

MAPPING (identification):
MATCHING [3] WITH ANDERSON MOUSE AND RAT LIVER 2-DE MAPS [1], AND WITH GIOMETTI MOUSE LIVER 2-DE MAP [2]; SPOTS 2D-00133T, 2D-00133U: Peptide mass fingerprinting [3].



MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
MUSCLE_MOUSE
  map experimental info
  protein estimated location
 
MUSCLE_MOUSE

MAP LOCATIONS:
pI=5.28; Mw=68618  [identification data]
pI=5.30; Mw=68049

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [3];
SPOT 2D-0016L8: Peptide mass fingerprinting [3].



NUCLEI_LIVER_MOUSE {Soluble nuclear proteins and matrix from liver tissue}
Mus musculus (Mouse)
Tissue: Liver
NUCLEI_LIVER_MOUSE
  map experimental info
  protein estimated location
 
NUCLEI_LIVER_MOUSE

MAP LOCATIONS:
pI=4.63; Mw=42060  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [3].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=5.25; Mw=65750
pI=5.27; Mw=65625
pI=5.29; Mw=65500
pI=5.02; Mw=39386  [identification data]

MAPPING (identification):
SPOTS 1AP*: MATCHING WITH THE MOUSE LIVER MASTER GEL [3];
SPOT 2D-001BIS: Peptide mass fingerprinting [3].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
COMPLUYEAST-2DPAGEP63017; HSP7C_MOUSE.
REPRODUCTION-2DPAGEP63017; P63017.
REPRODUCTION-2DPAGEIPI00323357; IPI00323357.
UCD-2DPAGEP63017; HSP7C_MOUSE.
UniProtKB/Swiss-ProtP63017; HSP7C_MOUSE.
World-2DPAGE RepositoryP63017; HSP7C_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameHSP7C_MOUSE
Primary accession numberP63017
Secondary accession number(s) P08109 P12225 Q3U6R0 Q3U764 Q3U7D7 Q3U7E2 Q3U9B4 Q3U9G0 Q3UGM0 Q5FWJ6 Q62373 Q62374 Q62375 Q6NZD0
Sequence was last modified on August 1, 1988 (version 1)
Annotations were last modified on September 21, 2011 (version 86)
Name and origin of the protein
DescriptionRecName: Full=Heat shock cognate 71 kDa protein; AltName: Full=Heat shock 70 kDa protein 8;
Gene nameName=Hspa8
Synonyms=Hsc70, Hsc73
Encoded onName=Hspa8; Synonyms=Hsc70, Hsc73
Keywords3D-structure; Acetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome; Repressor; Stress response; Transcription; Transcription regulation; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM19141; AAA37869.1; -; mRNA
EMBLU27129; AAC52836.1; -; mRNA
EMBLU73744; AAB18391.1; -; Genomic_DNA
EMBLAK035286; BAC29016.1; -; mRNA
EMBLAK075935; BAC36065.1; -; mRNA
EMBLAK145579; BAE26523.1; -; mRNA
EMBLAK146708; BAE27374.1; -; mRNA
EMBLAK146985; BAE27588.1; -; mRNA
EMBLAK147864; BAE28187.1; -; mRNA
EMBLAK150474; BAE29591.1; -; mRNA
EMBLAK150498; BAE29612.1; -; mRNA
EMBLAK150701; BAE29780.1; -; mRNA
EMBLAK150958; BAE29990.1; -; mRNA
EMBLAK151065; BAE30081.1; -; mRNA
EMBLAK151127; BAE30135.1; -; mRNA
EMBLAK151287; BAE30272.1; -; mRNA
EMBLAK151435; BAE30398.1; -; mRNA
EMBLAK151516; BAE30465.1; -; mRNA
EMBLAK151537; BAE30484.1; -; mRNA
EMBLAK151775; BAE30681.1; -; mRNA
EMBLAK151808; BAE30707.1; -; mRNA
EMBLAK151865; BAE30753.1; -; mRNA
EMBLAK151892; BAE30776.1; -; mRNA
EMBLAK151948; BAE30822.1; -; mRNA
EMBLAK151997; BAE30861.1; -; mRNA
EMBLAK152598; BAE31346.1; -; mRNA
EMBLAK152697; BAE31427.1; -; mRNA
EMBLAK152703; BAE31432.1; -; mRNA
EMBLAK152803; BAE31508.1; ALT_FRAME; mRNA
EMBLAK153032; BAE31664.1; -; mRNA
EMBLAK153834; BAE32204.1; -; mRNA
EMBLAK159479; BAE35116.1; -; mRNA
EMBLAK164000; BAE37581.1; -; mRNA
EMBLAK166643; BAE38912.1; -; mRNA
EMBLAK166721; BAE38970.1; -; mRNA
EMBLAK166767; BAE39005.1; -; mRNA
EMBLAK166776; BAE39012.1; -; mRNA
EMBLAK166808; BAE39036.1; -; mRNA
EMBLAK166830; BAE39053.1; -; mRNA
EMBLAK166846; BAE39065.1; -; mRNA
EMBLAK166861; BAE39076.1; -; mRNA
EMBLAK166873; BAE39084.1; -; mRNA
EMBLAK166908; BAE39109.1; -; mRNA
EMBLAK166910; BAE39111.1; -; mRNA
EMBLAK166913; BAE39113.1; -; mRNA
EMBLAK166933; BAE39127.1; -; mRNA
EMBLAK167043; BAE39211.1; -; mRNA
EMBLAK167121; BAE39269.1; -; mRNA
EMBLAK167122; BAE39270.1; -; mRNA
EMBLAK167134; BAE39280.1; -; mRNA
EMBLAK167163; BAE39304.1; -; mRNA
EMBLAK167218; BAE39344.1; -; mRNA
EMBLAK167229; BAE39353.1; -; mRNA
EMBLAK167845; BAE39865.1; -; mRNA
EMBLAK167910; BAE39917.1; -; mRNA
EMBLAK168492; BAE40379.1; -; mRNA
EMBLAK168519; BAE40398.1; -; mRNA
EMBLAK168542; BAE40419.1; -; mRNA
EMBLAK168711; BAE40553.1; -; mRNA
EMBLAK168750; BAE40590.1; -; mRNA
EMBLAK168776; BAE40612.1; -; mRNA
EMBLAK168887; BAE40704.1; -; mRNA
EMBLAK168934; BAE40745.1; -; mRNA
EMBLAK169093; BAE40876.1; -; mRNA
EMBLAK169179; BAE40957.1; -; mRNA
EMBLAK169236; BAE41004.1; -; mRNA
EMBLAK169293; BAE41049.1; -; mRNA
EMBLBC006722; AAH06722.1; -; mRNA
EMBLBC066191; AAH66191.1; -; mRNA
EMBLBC085486; AAH85486.1; -; mRNA
EMBLBC089322; AAH89322.1; -; mRNA
EMBLBC089457; AAH89457.1; -; mRNA
EMBLBC106193; AAI06194.1; -; mRNA
EMBLX54401; CAA38267.1; -; Genomic_DNA
EMBLX54402; CAA38268.1; -; Genomic_DNA
EMBLX54403; CAA38269.1; -; Genomic_DNA
IPIIPI00323357; -; .
PIRA45935; A45935; .
PIRJC4853; JC4853; .
RefSeqNP_112442.2; NM_031165.4; .
UniGeneMm.290774; -; .
UniGeneMm.336743; -; .
UniGeneMm.351377; -; .
UniGeneMm.412745; -; .
PDB3CQX; X-ray; 2.30 A; A/B=1-381
PDBsum3CQX; -; .
ProteinModelPortalP63017; -; .
SMRP63017; 1-621; .
DIPDIP-32353N; -; .
IntActP63017; 11; .
MINTMINT-189032; -; .
STRINGP63017; -; .
SWISS-2DPAGEP63017; -; .
COMPLUYEAST-2DPAGEP63017; -; .
REPRODUCTION-2DPAGEIPI00323357; -; .
REPRODUCTION-2DPAGEP63017; -; .
REPRODUCTION-2DPAGEQ6NZD0; -; .
UCD-2DPAGEP63017; -; .
PRIDEP63017; -; .
EnsemblENSMUST00000015800; ENSMUSP00000015800; ENSMUSG00000015656; .
GeneID15481; -; .
KEGGmmu:15481; -; .
UCSCuc009ozx.2; mouse; .
CTD3312; -; .
MGIMGI:105384; Hspa8; .
eggNOGroNOG06558; -; .
HOVERGENHBG051845; -; .
InParanoidP63017; -; .
OMAHQQKDLE; -; .
OrthoDBEOG4W6NVK; -; .
PhylomeDBP63017; -; .
NextBio288328; -; .
BgeeP63017; -; .
CleanExMM_HSPA8; -; .
GenevestigatorP63017; -; .
GermOnlineENSMUSG00000015656; Mus musculus; .
GOGO:0005829; C:cytosol; IDA:MGI; .
GOGO:0070062; C:extracellular vesicular exosome; IDA:MGI; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0042623; F:ATPase activity; coupled; IDA:MGI
GOGO:0051082; F:unfolded protein binding; IPI:MGI; .
GOGO:0051085; P:chaperone mediated protein folding requiring cofactor; IGI:MGI; .
GOGO:0045892; P:negative regulation of transcription; DNA-dependent; ISS:UniProtKB
GOGO:0051726; P:regulation of cell cycle; IDA:MGI; .
GOGO:0006950; P:response to stress; IEA:UniProtKB-KW; .
GOGO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW
InterProIPR018181; Heat_shock_70_CS; .
InterProIPR001023; Hsp70; .
InterProIPR013126; Hsp_70; .
PANTHERPTHR19375; Hsp70; 1; .
PfamPF00012; HSP70; 1; .
PRINTSPR00301; HEATSHOCK70; .
PROSITEPS00297; HSP70_1; 1; .
PROSITEPS00329; HSP70_2; 1; .
PROSITEPS01036; HSP70_3; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server