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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P68104




SWISS-2DPAGE:  P68104


P68104


General information about the entry
View entry in simple text format
Entry nameEF1A1_HUMAN
Primary accession numberP68104
Secondary accession number(s) P04720
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMarch 31, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Elongation factor 1-alpha 1; Short=EF-1-alpha-1; AltName: Full=Elongation factor Tu; Short=EF-Tu; AltName: Full=Eukaryotic elongation factor 1 A-1; Short=eEF1A-1; AltName: Full=Leukocyte receptor cluster member 7;.
Gene nameName=EEF1A1
Synonyms=EEF1A, EF1A, LENG7
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=47400  [identification data]
Mw=46437  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWP04720.
UCD-2DPAGEP68104; EF1A1_HUMAN.
UniProtKB/Swiss-ProtP68104; EF1A1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameEF1A1_HUMAN
Primary accession numberP68104
Secondary accession number(s) P04719 P04720
Sequence was last modified on August 13, 1987 (version 1)
Annotations were last modified on October 19, 2011 (version 100)
Name and origin of the protein
DescriptionRecName: Full=Elongation factor 1-alpha 1; Short=EF-1-alpha-1; AltName: Full=Elongation factor Tu; Short=EF-Tu; AltName: Full=Eukaryotic elongation factor 1 A-1; Short=eEF1A-1; AltName: Full=Leukocyte receptor cluster member 7;
Gene nameName=EEF1A1
Synonyms=EEF1A, EF1A, LENG7
Encoded onName=EEF1A1; Synonyms=EEF1A, EF1A, LENG7
Keywords3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Elongation factor; GTP-binding; Methylation; Nucleotide-binding; Nucleus; Phosphoprotein; Protein biosynthesis; Reference proteome; Transcription; Transcription regulation; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX03558; CAA27245.1; -; mRNA
EMBLJ04617; AAA52343.1; -; Genomic_DNA
EMBLX16869; CAA34756.1; -; mRNA
EMBLAY043301; AAK95378.1; -; mRNA
EMBLBC008587; AAH08587.1; -; mRNA
EMBLBC009733; AAH09733.1; -; mRNA
EMBLBC009875; AAH09875.1; -; mRNA
EMBLBC010735; AAH10735.1; -; mRNA
EMBLBC012891; AAH12891.1; -; mRNA
EMBLBC014224; AAH14224.1; -; mRNA
EMBLBC018150; AAH18150.1; -; mRNA
EMBLBC018641; AAH18641.1; -; mRNA
EMBLBC021686; AAH21686.1; -; mRNA
EMBLBC028674; AAH28674.1; -; mRNA
EMBLBC038339; AAH38339.1; -; mRNA
EMBLBC057391; AAH57391.1; -; mRNA
EMBLBC066893; AAH66893.1; -; mRNA
EMBLBC072385; AAH72385.1; -; mRNA
EMBLBC082268; AAH82268.1; -; mRNA
EMBLX03689; CAA27325.1; -; mRNA
EMBLM29548; AAA52367.1; ALT_INIT; mRNA
IPIIPI00396485; -; .
PIRB24977; EFHU1; .
RefSeqNP_001393.1; NM_001402.5; .
UniGeneHs.520703; -; .
UniGeneHs.535192; -; .
UniGeneHs.586423; -; .
UniGeneHs.695681; -; .
UniGeneHs.713109; -; .
PDB1SYW; Model; -; A=2-443
PDBsum1SYW; -; .
ProteinModelPortalP68104; -; .
SMRP68104; 2-443; .
IntActP68104; 104; .
MINTMINT-1180846; -; .
STRINGP68104; -; .
PhosphoSiteP68104; -; .
SWISS-2DPAGEP68104; -; .
OGPP68104; -; .
UCD-2DPAGEP68104; -; .
PRIDEP68104; -; .
EnsemblENST00000309268; ENSP00000339053; ENSG00000156508; .
EnsemblENST00000316292; ENSP00000339063; ENSG00000156508; .
EnsemblENST00000331523; ENSP00000330054; ENSG00000156508; .
GeneID1915; -; .
KEGGhsa:1915; -; .
UCSCuc003phi.1; human; .
CTD1915; -; .
H-InvDBHIX0006010; -; .
H-InvDBHIX0032108; -; .
HGNCHGNC:3189; EEF1A1; .
MIM130590; gene; .
neXtProtNX_P68104; -; .
PharmGKBPA27625; -; .
eggNOGprNOG14262; -; .
HOGENOMHBG307581; -; .
HOVERGENHBG000179; -; .
InParanoidP68104; -; .
OMASIETHHM; -; .
OrthoDBEOG40K7ZP; -; .
PhylomeDBP68104; -; .
ReactomeREACT_17015; Metabolism of proteins; .
ReactomeREACT_71; Gene Expression; .
NextBio7799; -; .
PMAP-CutDBP68104; -; .
ArrayExpressP68104; -; .
BgeeP68104; -; .
CleanExHS_EEF1A1; -; .
GenevestigatorP68104; -; .
GermOnlineENSG00000156508; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005853; C:eukaryotic translation elongation factor 1 complex; TAS:UniProtKB; .
GOGO:0005525; F:GTP binding; TAS:UniProtKB; .
GOGO:0003924; F:GTPase activity; IEA:InterPro; .
GOGO:0005515; F:protein binding; IPI:IntAct; .
GOGO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW; .
InterProIPR000795; ProtSyn_GTP-bd; .
InterProIPR009001; Transl_elong_EF1A/Init_IF2_C; .
InterProIPR004539; Transl_elong_EF1A_euk/arc; .
InterProIPR004161; Transl_elong_EFTu/EF1A_2; .
InterProIPR004160; Transl_elong_EFTu/EF1A_C; .
InterProIPR009000; Transl_elong_init/rib_B-barrel; .
PfamPF00009; GTP_EFTU; 1; .
PfamPF03144; GTP_EFTU_D2; 1; .
PfamPF03143; GTP_EFTU_D3; 1; .
PRINTSPR00315; ELONGATNFCT; .
SUPFAMSSF50465; Elong_init_C; 1; .
SUPFAMSSF50447; Translat_factor; 1; .
TIGRFAMsTIGR00483; EF-1_alpha; 1; .
PROSITEPS00301; EFACTOR_GTP; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server