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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: O15160




SWISS-2DPAGE:  O15160


O15160


General information about the entry
View entry in simple text format
Entry nameRPAC1_HUMAN
Primary accession numberO15160
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMarch 31, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=DNA-directed RNA polymerases I and III subunit RPAC1; Short=DNA-directed RNA polymerase I subunit C; Short=RNA polymerases I and III subunit AC1; AltName: Full=AC40; AltName: Full=DNA-directed RNA polymerases I and III 40 kDa polypeptide; Short=RPA40; AltName: Full=RPA39; AltName: Full=RPC40;.
Gene nameName=POLR1C
Synonyms=POLR1E
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=42495  [identification data]
Mw=41811  [identification data]

MAPPING (identification):
BAND 1D-001V8V: PEPTIDE MASS FINGERPRINTING [1]; Tandem mass spectrometry [1].



NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_2D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_2D_HUMAN

MAP LOCATIONS:
pI=5.50; Mw=42256  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
REPRODUCTION-2DPAGEIPI00217386; IPI00217386.
UniProtKB/Swiss-ProtO15160; RPAC1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameRPAC1_HUMAN
Primary accession numberO15160
Secondary accession number(s) O75395 Q5JTE3
Sequence was last modified on January 1, 1998 (version 1)
Annotations were last modified on October 19, 2011 (version 122)
Name and origin of the protein
DescriptionRecName: Full=DNA-directed RNA polymerases I and III subunit RPAC1; Short=DNA-directed RNA polymerase I subunit C; Short=RNA polymerases I and III subunit AC1; AltName: Full=AC40; AltName: Full=DNA-directed RNA polymerases I and III 40 kDa polypeptide; Short=RPA40; AltName: Full=RPA39; AltName: Full=RPC40;
Gene nameName=POLR1C
Synonyms=POLR1E
Encoded onName=POLR1C; Synonyms=POLR1E
KeywordsAcetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Disease mutation; DNA-directed RNA polymerase; Nucleus; Phosphoprotein; Reference proteome; Transcription.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF008442; AAC14354.1; -; mRNA
EMBLAF047441; AAC39892.1; -; mRNA
EMBLAL355802; CAI42629.1; -; Genomic_DNA
EMBLBC008863; AAH08863.1; -; mRNA
IPIIPI00005179; -; .
IPIIPI00217386; -; .
RefSeqNP_976035.1; NM_203290.2; .
UniGeneHs.727715; -; .
ProteinModelPortalO15160; -; .
SMRO15160; 46-346; .
DIPDIP-27587N; -; .
IntActO15160; 7; .
MINTMINT-1137932; -; .
STRINGO15160; -; .
PhosphoSiteO15160; -; .
SWISS-2DPAGEO15160; -; .
REPRODUCTION-2DPAGEIPI00217386; -; .
PRIDEO15160; -; .
EnsemblENST00000372389; ENSP00000361465; ENSG00000171453; .
GeneID9533; -; .
KEGGhsa:9533; -; .
UCSCuc003ovn.1; human; .
UCSCuc003ovo.1; human; .
CTD9533; -; .
GeneCardsGC06P043202; -; .
HGNCHGNC:20194; POLR1C; .
HPAHPA031010; -; .
MIM248390; phenotype; .
MIM610060; gene; .
neXtProtNX_O15160; -; .
Orphanet861; Treacher-Collins syndrome; .
PharmGKBPA134882004; -; .
HOGENOMHBG539019; -; .
HOVERGENHBG017743; -; .
InParanoidO15160; -; .
OMAGKCQRFL; -; .
PhylomeDBO15160; -; .
ReactomeREACT_1788; Transcription; .
NextBio35740; -; .
ArrayExpressO15160; -; .
BgeeO15160; -; .
CleanExHS_POLR1C; -; .
CleanExHS_POLR1E; -; .
GenevestigatorO15160; -; .
GermOnlineENSG00000171453; Homo sapiens; .
GOGO:0005736; C:DNA-directed RNA polymerase I complex; TAS:ProtInc; .
GOGO:0005654; C:nucleoplasm; TAS:Reactome; .
GOGO:0003677; F:DNA binding; IEA:InterPro; .
GOGO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc; .
GOGO:0046983; F:protein dimerization activity; IEA:InterPro; .
GOGO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome; .
GOGO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome; .
GOGO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome; .
InterProIPR001514; DNA-dir_RNA_pol_30-40kDasu_CS; .
InterProIPR011261; DNA-dir_RNA_pol_dimersation; .
InterProIPR011262; DNA-dir_RNA_pol_insert; .
InterProIPR009025; DNA-dir_RNA_pol_RBP11-like; .
InterProIPR011263; DNA-dir_RNA_pol_RpoA/D/Rpb3; .
Gene3DG3DSA:2.170.120.12; RNAP_insert; 1; .
PfamPF01000; RNA_pol_A_bac; 1; .
PfamPF01193; RNA_pol_L; 1; .
SMARTSM00662; RPOLD; 1; .
SUPFAMSSF56553; RNAP_insert; 1; .
SUPFAMSSF55257; RNAP_RBP11-like; 1; .
PROSITEPS00446; RNA_POL_D_30KD; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server