General information about the entry |
View entry in simple text format |
Entry name | RUVB1_HUMAN |
Primary accession number | Q9Y265 |
integrated into SWISS-2DPAGE on | November 9, 2001 (release 15) |
2D Annotations were last modified on | March 31, 2004 (version 1) |
General Annotations were last modified on | May 19, 2011 (version 9) |
Name and origin of the protein |
Description | RecName: Full=RuvB-like 1; EC=3.6.4.12; AltName: Full=49 kDa TATA box-binding protein-interacting protein; Short=49 kDa TBP-interacting protein; AltName: Full=54 kDa erythrocyte cytosolic protein; Short=ECP-54; AltName: Full=INO80 complex subunit H; AltName: Full=Nuclear matrix protein 238; Short=NMP 238; AltName: Full=Pontin 52; AltName: Full=TIP49a; AltName: Full=TIP60-associated protein 54-alpha; Short=TAP54-alpha;. |
Gene name | Name=RUVBL1 Synonyms=INO80H, NMP238, TIP49, TIP49A
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Annotated species | Homo sapiens (Human) [TaxID: 9606] |
Taxonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
References |
[1] |
MAPPING ON GEL PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J. ''''''Functional proteomic analysis of human nucleolus'';'';'' Mol. Biol. Cell. 13(1):4100-4109(2002)
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2D PAGE maps for identified proteins
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How to interpret a protein
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NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human)
Tissue: Cervix carcinoma
map experimental info protein estimated location
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NUCLEOLI_HELA_2D_HUMAN
MAP LOCATIONS:
MAPPING (identification): Peptide mass fingerprinting [1].
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Copyright |
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). |
Cross-references |
OGP-WWW | Q9Y265. |
REPRODUCTION-2DPAGE | Q9Y265; Q9Y265. |
Siena-2DPAGE | Q9Y265; RUVB1_HUMAN. |
UniProtKB/Swiss-Prot | Q9Y265; RUVB1_HUMAN. |
2D PAGE maps for identified proteins
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- How to interpret a protein map
- You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
- Warning 1: the displayed region reflects
an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information.
It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
- Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
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External data extracted from UniProtKB/Swiss-Prot |
Extracted from UniProtKB/Swiss-Prot, release: 2011_10 |
Entry name | RUVB1_HUMAN |
Primary accession number | Q9Y265 |
Secondary accession number(s) | B2R5S0 P82276 Q1KMR0 Q53HK5 Q53HL7 Q53Y27 Q9BSX9 |
Sequence was last modified on | November 1, 1999 (version 1) |
Annotations were last modified on | October 19, 2011 (version 123) |
Name and origin of the protein |
Description | RecName: Full=RuvB-like 1; EC=3.6.4.12; AltName: Full=49 kDa TATA box-binding protein-interacting protein; Short=49 kDa TBP-interacting protein; AltName: Full=54 kDa erythrocyte cytosolic protein; Short=ECP-54; AltName: Full=INO80 complex subunit H; AltName: Full=Nuclear matrix protein 238; Short=NMP 238; AltName: Full=Pontin 52; AltName: Full=TIP49a; AltName: Full=TIP60-associated protein 54-alpha; Short=TAP54-alpha; |
Gene name | Name=RUVBL1 Synonyms=INO80H, NMP238, TIP49, TIP49A |
Encoded on | Name=RUVBL1; Synonyms=INO80H, NMP238, TIP49, TIP49A |
Keywords | 3D-structure; Acetylation; Activator; Alternative splicing; ATP-binding; Cell cycle; Cell division; Chromatin regulator; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; DNA damage; DNA recombination; DNA repair; Growth regulation; Helicase; Hydrolase; Membrane; Mitosis; Nucleotide-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. |
Copyright |
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License |
Cross-references |
EMBL | AB012122; BAA28169.1; -; mRNA |
EMBL | AJ010058; CAA08986.1; -; mRNA |
EMBL | AF070735; AAC77819.1; -; mRNA |
EMBL | AF099084; AAD04427.1; -; mRNA |
EMBL | Y18418; CAB46271.1; -; mRNA |
EMBL | AF380344; AAM45570.1; -; Genomic_DNA |
EMBL | AF380343; AAM45570.1; JOINED; Genomic_DNA |
EMBL | DQ469310; ABF13334.1; -; mRNA |
EMBL | BT007057; AAP35706.1; -; mRNA |
EMBL | AK222563; BAD96283.1; -; mRNA |
EMBL | AK222575; BAD96295.1; -; mRNA |
EMBL | AK312290; BAG35217.1; -; mRNA |
EMBL | AB451224; BAG70038.1; -; mRNA |
EMBL | BC002993; AAH02993.1; -; mRNA |
EMBL | BC012886; AAH12886.1; -; mRNA |
IPI | IPI00021187; -; . |
IPI | IPI00788942; -; . |
PIR | JE0334; JE0334; . |
RefSeq | NP_003698.1; NM_003707.2; . |
UniGene | Hs.272822; -; . |
PDB | 2C9O; X-ray; 2.20 A; A/B/C=1-456 |
PDBsum | 2C9O; -; . |
ProteinModelPortal | Q9Y265; -; . |
SMR | Q9Y265; 7-449; . |
DIP | DIP-29937N; -; . |
IntAct | Q9Y265; 54; . |
MINT | MINT-1138777; -; . |
STRING | Q9Y265; -; . |
PhosphoSite | Q9Y265; -; . |
SWISS-2DPAGE | Q9Y265; -; . |
OGP | Q9Y265; -; . |
REPRODUCTION-2DPAGE | Q9Y265; -; . |
PeptideAtlas | Q9Y265; -; . |
PRIDE | Q9Y265; -; . |
Ensembl | ENST00000322623; ENSP00000318297; ENSG00000175792; . |
GeneID | 8607; -; . |
KEGG | hsa:8607; -; . |
UCSC | uc003ekf.1; human; . |
UCSC | uc003ekh.1; human; . |
CTD | 8607; -; . |
GeneCards | GC03M125180; -; . |
H-InvDB | HIX0021235; -; . |
HGNC | HGNC:10474; RUVBL1; . |
HPA | HPA019947; -; . |
HPA | HPA019948; -; . |
MIM | 603449; gene; . |
neXtProt | NX_Q9Y265; -; . |
PharmGKB | PA34887; -; . |
eggNOG | prNOG09539; -; . |
GeneTree | ENSGT00550000075043; -; . |
HOVERGEN | HBG054186; -; . |
InParanoid | Q9Y265; -; . |
OMA | VHKKKEV; -; . |
OrthoDB | EOG46Q6SH; -; . |
PhylomeDB | Q9Y265; -; . |
Reactome | REACT_22172; Chromosome Maintenance; . |
NextBio | 32249; -; . |
ArrayExpress | Q9Y265; -; . |
Bgee | Q9Y265; -; . |
CleanEx | HS_RUVBL1; -; . |
Genevestigator | Q9Y265; -; . |
GermOnline | ENSG00000175792; Homo sapiens; . |
GO | GO:0005794; C:Golgi apparatus; IDA:HPA; . |
GO | GO:0031011; C:Ino80 complex; IDA:UniProtKB; . |
GO | GO:0016020; C:membrane; IEA:UniProtKB-SubCell; . |
GO | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell; . |
GO | GO:0071339; C:MLL1 complex; IDA:UniProtKB; . |
GO | GO:0035267; C:NuA4 histone acetyltransferase complex; IDA:UniProtKB; . |
GO | GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell; . |
GO | GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . |
GO | GO:0003678; F:DNA helicase activity; IDA:UniProtKB; . |
GO | GO:0005515; F:protein binding; IPI:UniProtKB; . |
GO | GO:0051301; P:cell division; IEA:UniProtKB-KW; . |
GO | GO:0034080; P:CenH3-containing nucleosome assembly at centromere; TAS:Reactome; . |
GO | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW; . |
GO | GO:0006281; P:DNA repair; IEA:UniProtKB-KW; . |
GO | GO:0043968; P:histone H2A acetylation; IDA:UniProtKB; . |
GO | GO:0043967; P:histone H4 acetylation; IDA:UniProtKB; . |
GO | GO:0007067; P:mitosis; IEA:UniProtKB-KW; . |
GO | GO:0040008; P:regulation of growth; IEA:UniProtKB-KW; . |
GO | GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc; . |
GO | GO:0007283; P:spermatogenesis; TAS:ProtInc; . |
GO | GO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW |
InterPro | IPR003593; ATPase_AAA+_core; . |
InterPro | IPR016027; NA-bd_OB-fold-like; . |
InterPro | IPR010339; TIP49_C; . |
Pfam | PF06068; TIP49; 1; . |
SMART | SM00382; AAA; 1; . |
SUPFAM | SSF50249; Nucleic_acid_OB; 1; . |