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SWISS-2DPAGE is an annotated two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) and SDS-PAGE database established in 1993.

Until March 2011, SWISS-2DPAGE has been maintained, collaboratively, by the Biomedical Proteomics Reasearch Group (BPRG) of the Geneva University and the Proteome Informatics Group of the Swiss Institute of Bioinformatics (SIB). Since April 2011, SWISS-2DPAGE is being maintained by the Swiss-Prot and the Vital-IT of the Swiss Institute of Bioinformatics.

The SWISS-2DPAGE database assembles data on proteins identified on various 2-D PAGE and SDS-PAGE maps. Each SWISS-2DPAGE entry contains textual data on one protein, including mapping procedures, physiological and pathological information, experimental data (isoelectric point, molecular weight, amino acid composition, peptide masses) and bibliographical references. In addition to this textual data, SWISS-2DPAGE provides several 2-D PAGE and SDS-PAGE images showing the experimentally determined location of the protein, as well as a theoretical region computed from the sequence protein, indicating where the protein might be found in the gel.
Cross-references are provided to Medline and many other federated 2-DE databases, e.g. ( World-2DPAGE Repository, UCD-2DPAGE, Plasmo2Dbase, COMPLUYEAST 2D-PAGE DATABASE, REPRODUCTION-2DPAGE, 2DBase, Cornea-2DPAGE, OGP-WWW, PHCI-2DPAGE, Siena-2DPAGE, YEPD, and many other 2D-PAGE databases ) and to UniProtKB/Swiss-Prot, which provides many links to other databases (EMBL, Genbank, PROSITE, OMIM, etc).

The protein entries in SWISS-2DPAGE are text files structured in a format similar to the one used in Swiss-Prot original text format (for details see user manual).

For detailed information specific to the current SWISS-2DPAGE release, see the release notes.

If you want to cite SWISS-2DPAGE in a publication, see the references list.