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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: Q14847




SWISS-2DPAGE:  Q14847


Q14847


General information about the entry
View entry in simple text format
Entry nameLASP1_HUMAN
Primary accession numberQ14847
integrated into SWISS-2DPAGE on January 15, 1999 (release 9)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 10)
Name and origin of the protein
DescriptionRecName: Full=LIM and SH3 domain protein 1; Short=LASP-1; AltName: Full=Metastatic lymph node gene 50 protein; Short=MLN 50;.
Gene nameName=LASP1
Synonyms=MLN50
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F.
Submitted (JAN-1999) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)}
Homo sapiens (Human)
Tissue: Colon adenocarcinoma
DLD1_HUMAN
  map experimental info
  protein estimated location
 
DLD1_HUMAN

MAP LOCATIONS:
pI=6.30; Mw=34500  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWQ14847.
Siena-2DPAGEQ14847; LASP1_HUMAN.
UniProtKB/Swiss-ProtQ14847; LASP1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameLASP1_HUMAN
Primary accession numberQ14847
Secondary accession number(s) Q96ED2 Q96IG0
Sequence was last modified on January 1, 1998 (version 2)
Annotations were last modified on September 21, 2011 (version 113)
Name and origin of the protein
DescriptionRecName: Full=LIM and SH3 domain protein 1; Short=LASP-1; AltName: Full=Metastatic lymph node gene 50 protein; Short=MLN 50;
Gene nameName=LASP1
Synonyms=MLN50
Encoded onName=LASP1; Synonyms=MLN50
Keywords3D-structure; Acetylation; Actin-binding; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Ion transport; LIM domain; Metal-binding; Phosphoprotein; Reference proteome; Repeat; SH3 domain; Transport; Zinc.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX82456; CAA57833.1; -; mRNA
EMBLBC007560; AAH07560.1; -; mRNA
EMBLBC012460; AAH12460.1; -; mRNA
IPIIPI00000861; -; .
IPIIPI00386803; -; .
PIRS68234; S68234; .
RefSeqNP_006139.1; NM_006148.2; .
UniGeneHs.728766; -; .
PDB3I35; X-ray; 1.40 A; A=202-261
PDBsum3I35; -; .
ProteinModelPortalQ14847; -; .
SMRQ14847; 1-61; 205-261; .
IntActQ14847; 6; .
MINTMINT-5001286; -; .
STRINGQ14847; -; .
PhosphoSiteQ14847; -; .
SWISS-2DPAGEQ14847; -; .
OGPQ14847; -; .
PRIDEQ14847; -; .
EnsemblENST00000318008; ENSP00000325240; ENSG00000002834; .
GeneID3927; -; .
KEGGhsa:3927; -; .
UCSCuc002hra.1; human; .
CTD3927; -; .
GeneCardsGC17P032821; -; .
H-InvDBHIX0013769; -; .
HGNCHGNC:6513; LASP1; .
HPACAB022049; -; .
HPAHPA012072; -; .
MIM602920; gene; .
neXtProtNX_Q14847; -; .
PharmGKBPA30298; -; .
eggNOGprNOG04619; -; .
GeneTreeENSGT00530000062924; -; .
HOVERGENHBG054636; -; .
InParanoidQ14847; -; .
OMASIQRNAP; -; .
OrthoDBEOG4PVP0H; -; .
NextBio15423; -; .
ArrayExpressQ14847; -; .
BgeeQ14847; -; .
CleanExHS_LASP1; -; .
GenevestigatorQ14847; -; .
GermOnlineENSG00000002834; Homo sapiens; .
GOGO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB; .
GOGO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB; .
GOGO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc; .
GOGO:0008270; F:zinc ion binding; IEA:InterPro; .
InterProIPR013998; Nebulin; .
InterProIPR000900; Nebulin_35r-motif; .
InterProIPR001452; SH3_domain; .
InterProIPR001781; Znf_LIM; .
Gene3DG3DSA:2.10.110.10; Znf_LIM; 1; .
PANTHERPTHR11039; Nebulin; 1; .
PfamPF00412; LIM; 1; .
PfamPF00880; Nebulin; 2; .
PfamPF00018; SH3_1; 1; .
PRINTSPR00452; SH3DOMAIN; .
SMARTSM00132; LIM; 1; .
SMARTSM00227; NEBU; 2; .
SMARTSM00326; SH3; 1; .
SUPFAMSSF50044; SH3; 1; .
PROSITEPS00478; LIM_DOMAIN_1; 1; .
PROSITEPS50023; LIM_DOMAIN_2; 1; .
PROSITEPS51216; NEBULIN; 2; .
PROSITEPS50002; SH3; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server