Attention: World-2DPAGE is no longer maintained.

Sample Preparation and Post-separation Analysis

P16070:

ID   CD44_HUMAN; STANDARD; 2DG.
AC   P16070;
DT   01-SEP-1997, integrated into SWISS-2DPAGE (release 6).
DT   01-DEC-2000, 2D annotation version 2.
DT   19-MAY-2011, general annotation version 10.
DE   RecName: Full=CD44 antigen; AltName: Full=CDw44; AltName: Full=Epican;
DE   AltName: Full=Extracellular matrix receptor III; Short=ECMR-III; AltName:
DE   Full=GP90 lymphocyte homing/adhesion receptor; AltName: Full=HUTCH-I;
DE   AltName: Full=Heparan sulfate proteoglycan; AltName: Full=Hermes antigen;
DE   AltName: Full=Hyaluronate receptor; AltName: Full=Phagocytic glycoprotein
DE   1; Short=PGP-1; AltName: Full=Phagocytic glycoprotein I; Short=PGP-I;
DE   AltName: CD_antigen=CD44; Flags: Precursor;.
GN   Name=CD44; Synonyms=LHR, MDU2, MDU3, MIC4;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Hominidae; Homo.
OX   NCBI_TaxID=9606;
MT   CEC_HUMAN, DLD1_HUMAN.
IM   CEC_HUMAN, DLD1_HUMAN.
RN   [1]
RP   MAPPING ON GEL.
RX   MEDLINE=98163346; PubMed=9504818; [NCBI, Expasy, EBI, Israel, Japan]
RA   Reymond M.A., Sanchez J.-C., Hughes G.J., Riese J., Tortola S., Peinado
RA   M.A., Kirchner T., Hohenberger W., Hochstrasser D.F., Kockerling F.;
RT   ''''''Standardized characterization of gene expression in human
RT   colorectal epithelium by two-dimensional electrophoresis'';'';'';
RL   Electrophoresis 18(1):2842-2848(1997).
RN   [2]
RP   PROTEIN EXPRESSION.
RX   MEDLINE=96024065; PubMed=7553660; [NCBI, Expasy, EBI, Israel, Japan]
RA   Gunthert U., Stauder R., Mayer B., Terpe H.J., Finke L., Friedrichs K.;
RT   ''''''Are CD44 variant isoforms involved in human tumour progression?'';'';'';
RL   Cancer Surv. 24(1):19-42(1995).
RN   [3]
RP   MAPPING ON GEL.
RA   Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A.,
RA   Appel R.D., Hochstrasser D.F.;
RL   Submitted (JAN-1999) to SWISS-2DPAGE.
2D   -!- MASTER: CEC_HUMAN;
2D   -!-   PI/MW: SPOT 2D-000TTU=5.06/43699;
2D   -!-   PI/MW: SPOT 2D-0010AS=5.23/43168;
2D   -!-   PI/MW: SPOT 2D-0010AT=5.11/42731;
2D   -!-   EXPRESSION: HAS BEEN OBSERVED AS A VERY EARLY EVENT IN THE
2D         PROGRESSION  OF COLON CARCINOMA [2].
2D   -!-   MAPPING: IMMUNODETECTION [1].
2D   -!- MASTER: DLD1_HUMAN;
2D   -!-   PI/MW: SPOT 2D-001DI0=5.16/75169;
2D   -!-   PI/MW: SPOT 2D-001DI1=5.25/75561;
2D   -!-   PI/MW: SPOT 2D-001DIA=5.21/74392;
2D   -!-   MAPPING: IMMUNOBLOTTING [3].
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DR   UniProtKB/Swiss-Prot; P16070; CD44_HUMAN.
//

The following 2-D maps are available for this protein:

	Colorectal epithelia cells	Colorectal adenocarcinoma cell line (DL-1)

SWISS-2DPAGE (search AC)