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Sample Preparation and Post-separation Analysis
| Searching in 'SWISS-2DPAGE' for entry matching: P78527 |
SWISS-2DPAGE: P78527
P78527:
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ID PRKDC_HUMAN; STANDARD; 2DG.
AC P78527;
DT 15-MAY-2003, integrated into SWISS-2DPAGE (release 16).
DT 31-MAR-2004, 2D annotation version 1.
DT 19-MAY-2011, general annotation version 7.
DE RecName: Full=DNA-dependent protein kinase catalytic subunit;
DE Short=DNA-PK catalytic subunit; Short=DNA-PKcs; EC=2.7.11.1; AltName:
DE Full=DNPK1; AltName: Full=p460;.
GN Name=PRKDC; Synonyms=HYRC, HYRC1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Hominidae; Homo.
OX NCBI_TaxID=9606;
MT NUCLEOLI_HELA_1D_HUMAN.
IM NUCLEOLI_HELA_1D_HUMAN.
RN [1]
RP MAPPING ON GEL.
RX PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
RA Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C.,
RA Greco A., Hochstrasser D.F., Diaz J.-J.;
RT ''''''Functional proteomic analysis of human nucleolus'';'';'';
RL Mol. Biol. Cell. 13(1):4100-4109(2002).
CC -!- SUBUNIT: FORMS A COMPLEX WITH THE HETERODIMER KU70/KU80 AUTOANTIGEN.
CC INTERACTS WITH DNA-PKCS INTERACTING PROTEIN (KIP) WITH THE REGION
CC UPSTREAM THE KINASE DOMAIN
1D -!- MASTER: NUCLEOLI_HELA_1D_HUMAN;
1D -!- MW: BAND 1D-001V7L=94000;
1D -!- MW: BAND 1D-001V7N=94000;
1D -!- MW: BAND 1D-001V7O=94000;
1D -!- PEPTIDE SEQUENCES: BAND 1D-001V7N: (K)NLSSNEAISLEEIR(I),839-852;
1D (R)TVGALQVLGTEAQSSLLK(A),1275-1292; (K)NLLIFENLIDLK(R),1974-1985;
1D (K)LVINTEEVFRPYAK(H),2149-2162; (R)STVLTPMFVETQASQGTLQTR(T),2599-2619;
1D (R)RILELSGSSSEDSEK(V),3358-3372; (R)MoxSTSPEAFLALR(S),3890-3901.
1D -!- PEPTIDE SEQUENCES: BAND 1D-001V7O: (K)NLSSNEAISLEEIR(I),839-852;
1D (R)VVQMoxLGSLGGQINK(N),855-868; (R)TVGALQVLGTEAQSSLLK(A),1275-1292;
1D (K)CFGTGAAGNRTSPQEGER(Y),1312-1329; (K)NLDLAVLELMoxQSSVDNTK(M),1574-1591;
1D (K)INQVFHGSCITEGNELTK(T),1896-1913; (K)FYQGFLFSEKPEK(N),1961-1973;
1D (R)YNFPVEVEVPMER(K),1988-2000; (K)LVINTEEVFRPYAK(H),2149-2162;
1D (R)STVLTPMFVETQASQGTLQTR(T),2599-2619; (R)ATQQQHDFTLTQTADGR(S),2637-2653;
1D (K)LLLQGEADQSLLTFIDK(A),3051-3067; (R)CFFLSKIEEK(L),3187-3196;
1D (R)SQGCSEQVLTVLK(T),3290-3302; (R)RILELSGSSSEDSEK(V),3358-3372;
1D (R)NELEIPGQYDGR(G),3697-3708; (K)ETGLMoxYSIMoxVHALR(A),3976-3989.
1D -!- MAPPING: Tandem mass spectrometry [1].
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DR UniProtKB/Swiss-Prot; P78527; PRKDC_HUMAN.
//
The following 2-D map is available for this protein:
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SDS-PAGE of nucleolar proteins from Human HeLa cells
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SWISS-2DPAGE (search AC)
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