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Searching in 'World-2DPAGE Repository [0019]' for entry matching: 1433E_HUMAN




World-2DPAGE Repository (0019):  1433E_HUMAN


1433E_HUMAN


General information about the entry
View entry in simple text format
Entry name1433E_HUMAN
Primary accession numberP62258
Secondary accession number(s) Q4VJB6
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=14-3-3 protein epsilon; Short=14-3-3E;.
Gene nameName=YWHAE
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info
 
HIPP_SYNAP

MAP LOCATIONS:
pI=4.63; Mw=29326  [identification data]

IDENTIFICATION: SPOT 1074: Peptides number=14. SeqCov=54.1%. MOWSE score=1.06E+9 [1].
MAPPING (identification):
SPOT 1074: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP62258; 1433E_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name1433E_HUMAN
Primary accession numberP62258
Secondary accession number(s) B3KY71 D3DTH5 P29360 P42655 Q4VJB6 Q53XZ5 Q63631 Q7M4R4
Sequence was last modified on July 5, 2004 (version 1)
Annotations were last modified on December 14, 2011 (version 95)
Name and origin of the protein
DescriptionRecName: Full=14-3-3 protein epsilon; Short=14-3-3E;
Gene nameName=YWHAE
Encoded onName=YWHAE
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Host-virus interaction; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU20972; AAC50175.1; -; mRNA
EMBLU54778; AAC50710.1; -; mRNA
EMBLU43399; AAC50625.1; -; mRNA
EMBLU43430; AAD00026.1; -; mRNA
EMBLU28936; AAA75301.1; -; mRNA
EMBLAB017103; BAA32538.1; -; Genomic_DNA
EMBLAY883089; AAX68683.1; -; mRNA
EMBLAK128785; BAG54733.1; -; mRNA
EMBLAK295260; BAG58249.1; -; mRNA
EMBLAK316185; BAH14556.1; -; mRNA
EMBLBT007161; AAP35825.1; -; mRNA
EMBLCH471108; EAW90628.1; -; Genomic_DNA
EMBLCH471108; EAW90629.1; -; Genomic_DNA
EMBLBC000179; AAH00179.1; -; mRNA
EMBLBC001440; AAH01440.1; -; mRNA
IPIIPI00000816; -; .
IPIIPI00974544; -; .
PIRA61235; A61235; .
PIRI38947; I38947; .
RefSeqNP_006752.1; NM_006761.4; .
UniGeneHs.513851; -; .
PDB2BR9; X-ray; 1.75 A; A=1-233
PDBsum2BR9; -; .
ProteinModelPortalP62258; -; .
SMRP62258; 3-232; .
IntActP62258; 84; .
MINTMINT-4998623; -; .
STRINGP62258; -; .
PhosphoSiteP62258; -; .
DMDM51702210; -; .
OGPP42655; -; .
UCD-2DPAGEP62258; -; .
PeptideAtlasP62258; -; .
PRIDEP62258; -; .
EnsemblENST00000264335; ENSP00000264335; ENSG00000108953; .
GeneID7531; -; .
KEGGhsa:7531; -; .
UCSCuc002fsj.1; human; .
CTD7531; -; .
GeneCardsGC17M001148; -; .
H-InvDBHIX0013397; -; .
H-InvDBHIX0013751; -; .
H-InvDBHIX0030006; -; .
HGNCHGNC:12851; YWHAE; .
HPACAB016200; -; .
HPACAB021109; -; .
HPAHPA008445; -; .
MIM605066; gene; .
neXtProtNX_P62258; -; .
Orphanet217385; 17p13.3 microduplication syndrome; .
PharmGKBPA37440; -; .
eggNOGprNOG19467; -; .
HOVERGENHBG050423; -; .
InParanoidP62258; -; .
OMAKESALIM; -; .
OrthoDBEOG4HHP34; -; .
PhylomeDBP62258; -; .
Pathway_Interaction_DBa6b1_a6b4_integrin_pathway; a6b1 and a6b4 Integrin signaling; .
Pathway_Interaction_DBpi3kciaktpathway; Class I PI3K signaling events mediated by Akt; .
Pathway_Interaction_DBfoxopathway; FoxO family signaling; .
Pathway_Interaction_DBigf1_pathway; IGF1 pathway; .
Pathway_Interaction_DBinsulin_glucose_pathway; Insulin-mediated glucose transport; .
Pathway_Interaction_DBlis1pathway; Lissencephaly gene (LIS1) in neuronal migration and development; .
Pathway_Interaction_DBp38_mk2pathway; p38 signaling mediated by MAPKAP kinases; .
Pathway_Interaction_DBp75ntrpathway; p75(NTR)-mediated signaling; .
Pathway_Interaction_DBtelomerasepathway; Regulation of Telomerase; .
Pathway_Interaction_DBnfat_3pathway; Role of Calcineurin-dependent NFAT signaling in lymphocytes; .
Pathway_Interaction_DBhdac_classii_pathway; Signaling events mediated by HDAC Class II; .
Pathway_Interaction_DBtgfbrpathway; TGF-beta receptor signaling; .
Pathway_Interaction_DBpi3kplctrkpathway; Trk receptor signaling mediated by PI3K and PLC-gamma; .
ReactomeREACT_111102; Signal Transduction; .
ReactomeREACT_152; Cell Cycle; Mitotic; .
NextBio29461; -; .
PMAP-CutDBP62258; -; .
ArrayExpressP62258; -; .
BgeeP62258; -; .
CleanExHS_YWHAE; -; .
GenevestigatorP62258; -; .
GermOnlineENSG00000108953; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0042826; F:histone deacetylase binding; IPI:BHF-UCL; .
GOGO:0050815; F:phosphoserine binding; IPI:BHF-UCL; .
GOGO:0006915; P:apoptotic process; TAS:Reactome; .
GOGO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome; .
GOGO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome; .
GOGO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW; .
GOGO:0035556; P:intracellular signal transduction; TAS:ProtInc; .
GOGO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome; .
InterProIPR000308; 14-3-3; .
InterProIPR023409; 14-3-3_CS; .
InterProIPR023410; 14-3-3_domain; .
Gene3DG3DSA:1.20.190.20; 14-3-3; 1; .
KOK06630; -; .
PANTHERPTHR18860; 14-3-3; 1; .
PfamPF00244; 14-3-3; 1; .
PIRSFPIRSF000868; 14-3-3; 1; .
PRINTSPR00305; 1433ZETA; .
SMARTSM00101; 14_3_3; 1; .
SUPFAMSSF48445; 14-3-3; 1; .
PROSITEPS00796; 1433_1; 1; .
PROSITEPS00797; 1433_2; 1; .



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