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Searching in 'World-2DPAGE Repository [0019]' for entry matching: AATM_RAT




World-2DPAGE Repository (0019):  AATM_RAT

AATM_RAT


General information about the entry
View entry in simple text format
Entry nameAATM_RAT
Primary accession numberP00507
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Aspartate aminotransferase, mitochondrial; Short=mAspAT; EC=2.6.1.1; AltName: Full=Fatty acid-binding protein; Short=FABP-1; AltName: Full=Glutamate oxaloacetate transaminase 2; AltName: Full=Plasma membrane-associated fatty acid-binding protein; Short=FABPpm; AltName: Full=Transaminase A; Flags: Precursor;.
Gene nameName=Got2
Synonyms=Maat
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info 		 
HIPP_SYNAP

MAP LOCATIONS:
pI=9.13; Mw=47683  [identification data]
pI=9.13; Mw=47683  [identification data]

IDENTIFICATION: SPOT 1112: Peptides number=11. SeqCov=21.9%. MOWSE score=1.86E+5 [1]
SPOT 1200: Peptides number=8. SeqCov=27.7%. MOWSE score=8.00E+4 [1].
MAPPING (identification):
SPOT 1112: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1200: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP00507; AATM_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameAATM_RAT
Primary accession numberP00507
Secondary accession number(s) Q64551 Q9QV50
Sequence was last modified on July 1, 1989 (version 2)
Annotations were last modified on November 16, 2011 (version 111)
Name and origin of the protein
DescriptionRecName: Full=Aspartate aminotransferase, mitochondrial; Short=mAspAT; EC=2.6.1.1; AltName: Full=Fatty acid-binding protein; Short=FABP-1; AltName: Full=Glutamate oxaloacetate transaminase 2; AltName: Full=Plasma membrane-associated fatty acid-binding protein; Short=FABPpm; AltName: Full=Transaminase A; Flags: Precursor;
Gene nameName=Got2
Synonyms=Maat
Encoded onName=Got2; Synonyms=Maat
KeywordsAcetylation; Aminotransferase; Cell membrane; Complete proteome; Direct protein sequencing; Lipid transport; Membrane; Mitochondrion; Phosphoprotein; Pyridoxal phosphate; Reference proteome; Transferase; Transit peptide; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM18467; AAB54275.1; -; mRNA
EMBLBC061792; AAH61792.1; -; mRNA
EMBLU21158; AAC13868.1; -; Genomic_DNA
EMBLM12709; AAA41267.1; -; mRNA
IPIIPI00210920; -; .
PIRA28005; XNRTDM; .
PIRI55427; I55427; .
RefSeqNP_037309.1; NM_013177.2; .
UniGeneRn.98650; -; .
ProteinModelPortalP00507; -; .
SMRP00507; 30-430; .
IntActP00507; 1; .
STRINGP00507; -; .
PhosphoSiteP00507; -; .
PRIDEP00507; -; .
EnsemblENSRNOT00000015956; ENSRNOP00000015956; ENSRNOG00000011782; .
GeneID25721; -; .
KEGGrno:25721; -; .
NMPDRfig|10116.3.peg.14535; -; .
UCSCNM_013177; rat; .
CTD2806; -; .
RGD2722; Got2; .
eggNOGmaNOG12574; -; .
GeneTreeENSGT00390000014081; -; .
HOVERGENHBG000951; -; .
InParanoidP00507; -; .
OMAAYRDDNT; -; .
OrthoDBEOG4RXZ07; -; .
PhylomeDBP00507; -; .
BioCycMetaCyc:MONOMER-15069; -; .
BRENDA2.6.1.1; 5301; .
NextBio607817; -; .
ArrayExpressP00507; -; .
GenevestigatorP00507; -; .
GermOnlineENSRNOG00000011782; Rattus norvegicus; .
GOGO:0009986; C:cell surface; IDA:RGD; .
GOGO:0005743; C:mitochondrial inner membrane; IDA:RGD; .
GOGO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; .
GOGO:0043204; C:perikaryon; IDA:RGD; .
GOGO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0043234; C:protein complex; IDA:RGD; .
GOGO:0016597; F:amino acid binding; IDA:RGD; .
GOGO:0019899; F:enzyme binding; IDA:RGD; .
GOGO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; ISS:UniProtKB; .
GOGO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC; .
GOGO:0005543; F:phospholipid binding; IDA:RGD; .
GOGO:0042803; F:protein homodimerization activity; IMP:RGD; .
GOGO:0030170; F:pyridoxal phosphate binding; IDA:RGD; .
GOGO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB; .
GOGO:0006531; P:aspartate metabolic process; ISS:UniProtKB; .
GOGO:0009058; P:biosynthetic process; IEA:InterPro; .
GOGO:0015908; P:fatty acid transport; TAS:RGD; .
GOGO:0006536; P:glutamate metabolic process; ISS:UniProtKB; .
InterProIPR004839; Aminotransferase_I/II; .
InterProIPR000796; Asp_trans; .
InterProIPR004838; NHTrfase_class1_PyrdxlP-BS; .
InterProIPR015424; PyrdxlP-dep_Trfase_major_dom; .
InterProIPR015421; PyrdxlP-dep_Trfase_major_sub1; .
Gene3DG3DSA:3.40.640.10; PyrdxlP-dep_Trfase_major_sub1; 1; .
KOK14455; -; .
PANTHERPTHR11879; Asp_trans; 1; .
PfamPF00155; Aminotran_1_2; 1; .
PRINTSPR00799; TRANSAMINASE; .
SUPFAMSSF53383; PyrdxlP-dep_Trfase_major; 1; .
PROSITEPS00105; AA_TRANSFER_CLASS_1; 1; .


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