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Searching in 'World-2DPAGE Repository [0022]' for entry matching: CBR1_RAT World-2DPAGE Repository (0022):  CBR1_RAT CBR1_RAT General information about the entry View entry in simple text format Entry name CBR1_RAT Primary accession number P47727 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Carbonyl reductase [NADPH] 1; EC=1.1.1.184; AltName: Full=15-hydroxyprostaglandin dehydrogenase [NADP+]; EC=1.1.1.197; AltName: Full=20-beta-hydroxysteroid dehydrogenase; AltName: Full=NADPH-dependent carbonyl reductase 1; AltName: Full=Prostaglandin 9-ketoreductase; AltName: Full=Prostaglandin-E(2) 9-reductase; EC=1.1.1.189;. Gene name Name=Cbr1 Synonyms=Cbr Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 251: pI=8.22; Mw=30844   [identification data] IDENTIFICATION: SPOT 251: SeqCov=30.7%. Peptides MS=8/20. Mascot PMF Score=70 [1]. PEPTIDE EVIDENCE: SPOT 251: 59-FHQLDIDNPQSIR-71 (72) [1]. MAPPING (identification): SPOT 251: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P47727; CBR1_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name CBR1_RAT Primary accession number P47727 Secondary accession number(s) O08558 Q3KR58 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  November 16, 2011 (version 94) Name and origin of the protein Description RecName: Full=Carbonyl reductase [NADPH] 1; EC=1.1.1.184; AltName: Full=15-hydroxyprostaglandin dehydrogenase [NADP+]; EC=1.1.1.197; AltName: Full=20-beta-hydroxysteroid dehydrogenase; AltName: Full=NADPH-dependent carbonyl reductase 1; AltName: Full=Prostaglandin 9-ketoreductase; AltName: Full=Prostaglandin-E(2) 9-reductase; EC=1.1.1.189; Gene name Name=Cbr1 Synonyms=Cbr Encoded on Name=Cbr1; Synonyms=Cbr Keywords Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; NADP; Oxidoreductase; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X84349; CAA59088.1; -; mRNA EMBL X95986; CAA65230.1; -; Genomic_DNA EMBL D89069; BAA19007.1; -; mRNA EMBL BC105893; AAI05894.1; -; mRNA IPI IPI00331856; -; . PIR S68982; JC5284; . RefSeq NP_062043.1; NM_019170.2; . RefSeq XP_002727909.1; XM_002727863.1; . UniGene Rn.155297; -; . UniGene Rn.3425; -; . ProteinModelPortal P47727; -; . SMR P47727; 7-277; . STRING P47727; -; . PRIDE P47727; -; . Ensembl ENSRNOT00000041838; ENSRNOP00000051107; ENSRNOG00000032165; . Ensembl ENSRNOT00000042283; ENSRNOP00000043385; ENSRNOG00000032830; . GeneID 100360507; -; . GeneID 29224; -; . KEGG rno:100360507; -; . KEGG rno:29224; -; . UCSC NM_019170; rat; . CTD 873; -; . RGD 2286; Cbr1; . eggNOG roNOG06780; -; . HOVERGEN HBG001909; -; . InParanoid P47727; -; . OrthoDB EOG4BP1CB; -; . NextBio 608431; -; . Genevestigator P47727; -; . GermOnline ENSRNOG00000032165; Rattus norvegicus; . GO GO:0005829; C:cytosol; TAS:RGD; . GO GO:0005792; C:microsome; IDA:RGD; . GO GO:0005902; C:microvillus; IDA:RGD; . GO GO:0005634; C:nucleus; IDA:RGD; . GO GO:0005886; C:plasma membrane; IDA:RGD; . GO GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC; . GO GO:0005488; F:binding; IEA:InterPro; . GO GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB; . GO GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC; . GO GO:0017144; P:drug metabolic process; ISS:UniProtKB; . GO GO:0001542; P:ovulation from ovarian follicle; IEP:RGD; . GO GO:0018205; P:peptidyl-lysine modification; NAS:RGD; . GO GO:0042376; P:phylloquinone catabolic process; IDA:RGD; . GO GO:0034698; P:response to gonadotropin stimulus; IEP:RGD; . GO GO:0033574; P:response to testosterone stimulus; IEP:RGD; . InterPro IPR002198; DH_sc/Rdtase_SDR; . InterPro IPR002347; Glc/ribitol_DH; . InterPro IPR016040; NAD(P)-bd_dom; . InterPro IPR020904; Sc_DH/Rdtase_CS; . Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1; . KO K00079; -; . Pfam PF00106; adh_short; 1; . PRINTS PR00081; GDHRDH; . PRINTS PR00080; SDRFAMILY; . PROSITE PS00061; ADH_SHORT; 1; . World-2DPAGE Repository (search AC)