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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: ETFA_HUMAN World-2DPAGE Repository (0054):  ETFA_HUMAN ETFA_HUMAN General information about the entry View entry in simple text format Entry name ETFA_HUMAN Primary accession number P13804 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Electron transfer flavoprotein subunit alpha, mitochondrial; Short=Alpha-ETF; Flags: Precursor;. Gene name Name=ETFA Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 985: pI=8.62; Mw=35080   [identification data] %COV: SPOT 985: 56 [1]. SCORE: SPOT 985: 326 [1]. SEARCH ENGINE: SPOT 985: Mascot [1]. MAPPING (identification): SPOT 985: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P13804; ETFA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ETFA_HUMAN Primary accession number P13804 Secondary accession number(s) B4DT43 Q53XN3 Sequence was last modified on  January 1, 1990 (version 1) Annotations were last modified on  October 1, 2014 (version 164) Name and origin of the protein Description RecName: Full=Electron transfer flavoprotein subunit alpha, mitochondrial; Short=Alpha-ETF; Flags: Precursor; Gene name Name=ETFA Encoded on Name=ETFA Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Disease mutation; Electron transport; FAD; Flavoprotein; Glutaricaciduria; Mitochondrion; Polymorphism; Reference proteome; Transit peptide; Transport. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J04058; AAA52406.1; -; mRNA EMBL S55815; -; NOT_ANNOTATED_CDS; mRNA EMBL S55816; -; NOT_ANNOTATED_CDS; mRNA EMBL AJ224002; CAA11802.1; -; Genomic_DNA EMBL AF436657; AAN03712.1; -; Genomic_DNA EMBL AF436646; AAN03712.1; JOINED; Genomic_DNA EMBL AF436647; AAN03712.1; JOINED; Genomic_DNA EMBL AF436648; AAN03712.1; JOINED; Genomic_DNA EMBL AF436649; AAN03712.1; JOINED; Genomic_DNA EMBL AF436650; AAN03712.1; JOINED; Genomic_DNA EMBL AF436651; AAN03712.1; JOINED; Genomic_DNA EMBL AF436652; AAN03712.1; JOINED; Genomic_DNA EMBL AF436653; AAN03712.1; JOINED; Genomic_DNA EMBL AF436654; AAN03712.1; JOINED; Genomic_DNA EMBL AF436655; AAN03712.1; JOINED; Genomic_DNA EMBL AF436656; AAN03712.1; JOINED; Genomic_DNA EMBL BT009796; AAP88798.1; -; mRNA EMBL AK292979; BAF85668.1; -; mRNA EMBL AK300044; BAG61855.1; -; mRNA EMBL AC027243; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC091100; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471136; EAW99221.1; -; Genomic_DNA EMBL BC015526; AAH15526.1; -; mRNA EMBL BC095457; AAH95457.1; -; mRNA CCDS CCDS32299.1; -. [P13804-1]; . CCDS CCDS45311.1; -. [P13804-2]; . PIR A31998; A31998; . RefSeq NP_000117.1; NM_000126.3. [P13804-1]; . RefSeq NP_001121188.1; NM_001127716.1. [P13804-2]; . UniGene Hs.39925; -; . PDB 1EFV; X-ray; 2.10 A; A=20-333 PDB 1T9G; X-ray; 2.90 A; R=1-333 PDB 2A1T; X-ray; 2.80 A; R=1-333 PDB 2A1U; X-ray; 2.11 A; A=1-333 PDBsum 1EFV; -; . PDBsum 1T9G; -; . PDBsum 2A1T; -; . PDBsum 2A1U; -; . ProteinModelPortal P13804; -; . SMR P13804; 20-331; . BioGrid 108409; 16; . DIP DIP-6161N; -; . IntAct P13804; 7; . MINT MINT-5002447; -; . STRING 9606.ENSP00000267950; -; . PhosphoSite P13804; -; . DMDM 119636; -; . UCD-2DPAGE P13804; -; . MaxQB P13804; -; . PaxDb P13804; -; . PeptideAtlas P13804; -; . PRIDE P13804; -; . DNASU 2108; -; . Ensembl ENST00000433983; ENSP00000399273; ENSG00000140374. [P13804-2]; . Ensembl ENST00000557943; ENSP00000452762; ENSG00000140374. [P13804-1]; . GeneID 2108; -; . KEGG hsa:2108; -; . UCSC uc002bbt.2; human. [P13804-1]; . UCSC uc010bkq.1; human. [P13804-2]; . CTD 2108; -; . GeneCards GC15M076508; -; . HGNC HGNC:3481; ETFA; . HPA HPA018990; -; . HPA HPA018993; -; . HPA HPA018996; -; . HPA HPA024089; -; . MIM 231680; phenotype; . MIM 608053; gene; . neXtProt NX_P13804; -; . Orphanet 394532; Multiple acyl-CoA dehydrogenation deficiency; mild type; . Orphanet 394529; Multiple acyl-CoA dehydrogenation deficiency; severe neonatal type; . PharmGKB PA27897; -; . eggNOG COG2025; -; . HOGENOM HOG000247865; -; . HOVERGEN HBG002317; -; . InParanoid P13804; -; . KO K03522; -; . OMA TITAAKH; -; . OrthoDB EOG76MK8R; -; . PhylomeDB P13804; -; . TreeFam TF105763; -; . Reactome REACT_22393; Respiratory electron transport; . EvolutionaryTrace P13804; -; . GeneWiki ETFA; -; . GenomeRNAi 2108; -; . NextBio 8523; -; . PRO PR:P13804; -; . ArrayExpress P13804; -; . Bgee P13804; -; . CleanEx HS_ETFA; -; . Genevestigator P13804; -; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt; . GO GO:0005759; C:mitochondrial matrix; TAS:Reactome; . GO GO:0005739; C:mitochondrion; IDA:UniProt; . GO GO:0009055; F:electron carrier activity; IDA:UniProtKB; . GO GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB; . GO GO:0016491; F:oxidoreductase activity; IDA:UniProtKB; . GO GO:0044237; P:cellular metabolic process; TAS:Reactome; . GO GO:0022904; P:respiratory electron transport chain; TAS:Reactome; . GO GO:0044281; P:small molecule metabolic process; TAS:Reactome; . Gene3D 3.40.50.1220; -; 1; . Gene3D 3.40.50.620; -; 1; . InterPro IPR029035; DHS-like_NAD/FAD-binding_dom; . InterPro IPR001308; ETF_a; . InterPro IPR014730; ETF_a/b_N; . InterPro IPR014731; ETF_asu_C; . InterPro IPR018206; ETF_asu_C_CS; . InterPro IPR014729; Rossmann-like_a/b/a_fold; . Pfam PF01012; ETF; 1; . Pfam PF00766; ETF_alpha; 1; . PIRSF PIRSF000089; Electra_flavoP_a; 1; . SMART SM00893; ETF; 1; . SUPFAM SSF52467; SSF52467; 1; . PROSITE PS00696; ETF_ALPHA; 1; . World-2DPAGE Repository (search AC)