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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: GANAB_HUMAN World-2DPAGE Repository (0054):  GANAB_HUMAN GANAB_HUMAN General information about the entry View entry in simple text format Entry name GANAB_HUMAN Primary accession number Q14697 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Neutral alpha-glucosidase AB; EC=3.2.1.84; AltName: Full=Alpha-glucosidase 2; AltName: Full=Glucosidase II subunit alpha; Flags: Precursor;. Gene name Name=GANAB Synonyms=G2AN, KIAA0088 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 366: pI=5.58; Mw=103975   [identification data] %COV: SPOT 366: 21 [1]. SCORE: SPOT 366: 165 [1]. SEARCH ENGINE: SPOT 366: Mascot [1]. MAPPING (identification): SPOT 366: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot Q14697; GANAB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GANAB_HUMAN Primary accession number Q14697 Secondary accession number(s) A6NC20 Q8WTS9 Q9P0X0 Sequence was last modified on  July 5, 2004 (version 3) Annotations were last modified on  October 1, 2014 (version 130) Name and origin of the protein Description RecName: Full=Neutral alpha-glucosidase AB; EC=3.2.1.84; AltName: Full=Alpha-glucosidase 2; AltName: Full=Glucosidase II subunit alpha; Flags: Precursor; Gene name Name=GANAB Synonyms=G2AN, KIAA0088 Encoded on Name=GANAB; Synonyms=G2AN, KIAA0088 Keywords Alternative splicing; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Glycoprotein; Glycosidase; Golgi apparatus; Hydrolase; Polymorphism; Reference proteome; Signal. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AJ000332; CAA04006.1; -; mRNA EMBL AF144074; AAF66685.1; -; mRNA EMBL AP001458; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL D42041; BAA07642.1; -; mRNA EMBL BC017433; AAH17433.2; -; mRNA EMBL BC017435; AAH17435.2; -; mRNA EMBL BC065266; AAH65266.1; ALT_SEQ; mRNA CCDS CCDS41656.1; -. [Q14697-2]; . CCDS CCDS8026.1; -. [Q14697-1]; . RefSeq NP_001265121.1; NM_001278192.1; . RefSeq NP_001265122.1; NM_001278193.1; . RefSeq NP_001265123.1; NM_001278194.1; . RefSeq NP_938148.1; NM_198334.2. [Q14697-1]; . RefSeq NP_938149.2; NM_198335.3. [Q14697-2]; . UniGene Hs.595071; -; . ProteinModelPortal Q14697; -; . SMR Q14697; 249-911; . BioGrid 116802; 65; . IntAct Q14697; 17; . MINT MINT-5001279; -; . STRING 9606.ENSP00000340466; -; . BindingDB Q14697; -; . ChEMBL CHEMBL2519; -; . CAZy GH31; Glycoside Hydrolase Family 31; . PhosphoSite Q14697; -; . DMDM 54037162; -; . REPRODUCTION-2DPAGE IPI00383581; -; . MaxQB Q14697; -; . PaxDb Q14697; -; . PRIDE Q14697; -; . DNASU 23193; -; . Ensembl ENST00000346178; ENSP00000340466; ENSG00000089597. [Q14697-2]; . Ensembl ENST00000356638; ENSP00000349053; ENSG00000089597. [Q14697-1]; . Ensembl ENST00000526210; ENSP00000433799; ENSG00000089597. [Q14697-3]; . Ensembl ENST00000532402; ENSP00000432181; ENSG00000089597. [Q14697-3]; . Ensembl ENST00000534613; ENSP00000434921; ENSG00000089597. [Q14697-3]; . GeneID 23193; -; . KEGG hsa:23193; -; . UCSC uc001nua.4; human. [Q14697-2]; . UCSC uc001nub.4; human. [Q14697-1]; . CTD 23193; -; . GeneCards GC11M062430; -; . HGNC HGNC:4138; GANAB; . HPA HPA026874; -; . MIM 104160; gene; . neXtProt NX_Q14697; -; . PharmGKB PA28551; -; . eggNOG COG1501; -; . HOVERGEN HBG051683; -; . KO K05546; -; . OMA AIDDQLY; -; . OrthoDB EOG7VQJDS; -; . PhylomeDB Q14697; -; . TreeFam TF300337; -; . BRENDA 3.2.1.84; 2681; . Reactome REACT_23810; Calnexin/calreticulin cycle; . Reactome REACT_23878; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; . UniPathway UPA00957; -; . ChiTaRS GANAB; human; . GeneWiki GANAB; -; . GenomeRNAi 23193; -; . NextBio 44685; -; . PRO PR:Q14697; -; . ArrayExpress Q14697; -; . Bgee Q14697; -; . CleanEx HS_GANAB; -; . Genevestigator Q14697; -; . GO GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt; . GO GO:0017177; C:glucosidase II complex; IEA:Ensembl; . GO GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell; . GO GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0030246; F:carbohydrate binding; IEA:InterPro; . GO GO:0033919; F:glucan 1; 3-alpha-glucosidase activity; IEA:UniProtKB-EC GO GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . GO GO:0044267; P:cellular protein metabolic process; TAS:Reactome; . GO GO:0043687; P:post-translational protein modification; TAS:Reactome; . GO GO:0006457; P:protein folding; TAS:Reactome; . GO GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome; . InterPro IPR011013; Gal_mutarotase_SF_dom; . InterPro IPR000322; Glyco_hydro_31; . InterPro IPR025887; Glyco_hydro_31_N_dom; . InterPro IPR017853; Glycoside_hydrolase_SF; . Pfam PF13802; Gal_mutarotas_2; 1; . Pfam PF01055; Glyco_hydro_31; 1; . SUPFAM SSF51445; SSF51445; 1; . SUPFAM SSF74650; SSF74650; 2; . PROSITE PS00129; GLYCOSYL_HYDROL_F31_1; 1; . PROSITE PS00707; GLYCOSYL_HYDROL_F31_2; 1; . World-2DPAGE Repository (search AC)