Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: GRP75_RAT World-2DPAGE Repository (0022):  GRP75_RAT GRP75_RAT General information about the entry View entry in simple text format Entry name GRP75_RAT Primary accession number P48721 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Stress-70 protein, mitochondrial; AltName: Full=75 kDa glucose-regulated protein; Short=GRP-75; AltName: Full=Heat shock 70 kDa protein 9; AltName: Full=Mortalin; AltName: Full=Peptide-binding protein 74; Short=PBP74; AltName: Full=mtHSP70; Flags: Precursor;. Gene name Name=Hspa9 Synonyms=Grp75, Hspa9a Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 785: pI=5.97; Mw=74097   [identification data] SPOT 790: pI=5.97; Mw=74097   [identification data] IDENTIFICATION: SPOT 785: SeqCov=20%. Peptides MS=12/20. Mascot PMF Score=84 [1] SPOT 790: SeqCov=11.9%. Peptides MS=7/20. Mascot PMF Score=33 [1]. PEPTIDE EVIDENCE: SPOT 785: 378-SDIGEVILVGGMTR-391 (104) / 378-SDIGEVILVGGMTR-391 Oxidation (M) (48) / 499-LLGQFTLIGIPPAPR-513 (70) [1] SPOT 790: 378-SDIGEVILVGGMTR-391 (81) / 378-SDIGEVILVGGMTR-391 Oxidation (M) (37) / 499-LLGQFTLIGIPPAPR-513 (57) [1]. MAPPING (identification): SPOT 785: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 790: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P48721; GRP75_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name GRP75_RAT Primary accession number P48721 Sequence was last modified on  October 17, 2006 (version 3) Annotations were last modified on  November 16, 2011 (version 95) Name and origin of the protein Description RecName: Full=Stress-70 protein, mitochondrial; AltName: Full=75 kDa glucose-regulated protein; Short=GRP-75; AltName: Full=Heat shock 70 kDa protein 9; AltName: Full=Mortalin; AltName: Full=Peptide-binding protein 74; Short=PBP74; AltName: Full=mtHSP70; Flags: Precursor; Gene name Name=Hspa9 Synonyms=Grp75, Hspa9a Encoded on Name=Hspa9; Synonyms=Grp75, Hspa9a Keywords Acetylation; ATP-binding; Chaperone; Complete proteome; Direct protein sequencing; Mitochondrion; Nucleotide-binding; Phosphoprotein; Reference proteome; Transit peptide. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL S75280; AAB33049.1; -; mRNA EMBL S78556; AAB34982.1; -; mRNA IPI IPI00363265; -; . PIR I56581; I56581; . RefSeq NP_001094128.1; NM_001100658.1; . UniGene Rn.7535; -; . ProteinModelPortal P48721; -; . SMR P48721; 55-580; . IntAct P48721; 2; . MINT MINT-4592308; -; . STRING P48721; -; . PhosphoSite P48721; -; . World-2DPAGE 0004:P48721; -; . PRIDE P48721; -; . GeneID 291671; -; . KEGG rno:291671; -; . UCSC S78556; rat; . CTD 3313; -; . RGD 1311806; Hspa9; . eggNOG maNOG05443; -; . GeneTree ENSGT00550000074813; -; . HOVERGEN HBG051845; -; . InParanoid P48721; -; . OrthoDB EOG49KFQ6; -; . PhylomeDB P48721; -; . NextBio 632983; -; . ArrayExpress P48721; -; . Genevestigator P48721; -; . GermOnline ENSRNOG00000019525; Rattus norvegicus; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0051082; F:unfolded protein binding; IEA:InterPro; . GO GO:0006457; P:protein folding; IEA:InterPro; . InterPro IPR012725; Chaperone_DnaK; . InterPro IPR018181; Heat_shock_70_CS; . InterPro IPR001023; Hsp70; . InterPro IPR013126; Hsp_70; . KO K04043; -; . PANTHER PTHR19375; Hsp70; 1; . Pfam PF00012; HSP70; 1; . PRINTS PR00301; HEATSHOCK70; . TIGRFAMs TIGR02350; Prok_dnaK; 1; . PROSITE PS00297; HSP70_1; 1; . PROSITE PS00329; HSP70_2; 1; . PROSITE PS01036; HSP70_3; 1; . World-2DPAGE Repository (search AC)