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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0043]' for entry matching: GRP78_MOUSE World-2DPAGE Repository (0043):  GRP78_MOUSE GRP78_MOUSE General information about the entry View entry in simple text format Entry name GRP78_MOUSE Primary accession number P20029 integrated into World-2DPAGE Repository (0043) on  January 4, 2012 (release 1) 2D Annotations were last modified on January 6, 2012 (version 1) General Annotations were last modified on  April 18, 2012 (version 2) Name and origin of the protein Description RecName: Full=78 kDa glucose-regulated protein; Short=GRP-78; AltName: Full=Heat shock 70 kDa protein 5; AltName: Full=Immunoglobulin heavy chain-binding protein; Short=BiP; Flags: Precursor;. Gene name Name=Hspa5 Synonyms=Grp78 Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D GEL CHARACTERIZATION DOI=10.1016/j.jprot.2012.04.001 ; Sun Z., Biela L.M., Hamilton K.L., Reardon K.F. ''Concentration-dependent effects of the soy phytoestrogen genistein on the proteome of cultured cardiomyocytes'' Journal of Proteomics 0(0):0-0 (2012) 2D PAGE maps for identified proteins How to interpret a protein MMUSCULUS_HL-1PHO_4-7 {mouse HL-1 cultured cardiomyocytes hydrophobic extraction} Mus musculus (Mouse) Tissue: Cardiac myocyte   map experimental info   MMUSCULUS_HL-1PHO_4-7 MAP LOCATIONS: BAND pho28: Mw=72492   [identification data] %COV: BAND pho28: 8.65 [1]. GENEID: BAND pho28: GRP78_MOUSE [1]. SCORE: BAND pho28: 318 [1]. SEARCH ENGINE: BAND pho28: Mascot [1]. MAPPING (identification): BAND pho28: Tandem mass spectrometry [1]. Copyright Data from Dr. Zeyu Sun, Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, USA Cross-references IPI 00319992. UniProtKB/Swiss-Prot P20029; GRP78_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2012_03 Entry name GRP78_MOUSE Primary accession number P20029 Secondary accession number(s) O35642 Q3UFF2 Q61630 Sequence was last modified on  November 1, 1997 (version 3) Annotations were last modified on  February 22, 2012 (version 126) Name and origin of the protein Description RecName: Full=78 kDa glucose-regulated protein; Short=GRP-78; AltName: Full=Heat shock 70 kDa protein 5; AltName: Full=Immunoglobulin heavy chain-binding protein; Short=BiP; Flags: Precursor; Gene name Name=Hspa5 Synonyms=Grp78 Encoded on Name=Hspa5; Synonyms=Grp78 Keywords Acetylation; ATP-binding; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Nitration; Nucleotide-binding; Phosphoprotein; Reference proteome; Signal. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AJ002387; CAA05361.1; -; mRNA EMBL M19351; AAA37315.1; -; mRNA EMBL D78645; BAA11462.1; -; mRNA EMBL AK076079; BAC36166.1; -; mRNA EMBL AK146647; BAE27328.1; -; mRNA EMBL AK148539; BAE28609.1; -; mRNA EMBL AK151647; BAE30576.1; -; mRNA EMBL AK152020; BAE30882.1; -; mRNA EMBL AK166739; BAE38982.1; -; mRNA EMBL AK169034; BAE40825.1; -; mRNA EMBL BC050927; AAH50927.1; -; mRNA EMBL U16277; AAA76734.1; -; Genomic_DNA EMBL M30779; AAA37742.1; -; mRNA IPI IPI00319992; -; . PIR A37048; A37048; . RefSeq NP_001156906.1; NM_001163434.1; . RefSeq NP_071705.3; NM_022310.3; . UniGene Mm.330160; -; . UniGene Mm.470180; -; . ProteinModelPortal P20029; -; . SMR P20029; 27-636; . DIP DIP-32341N; -; . IntAct P20029; 11; . MINT MINT-1177274; -; . STRING P20029; -; . PhosphoSite P20029; -; . SWISS-2DPAGE P20029; -; . COMPLUYEAST-2DPAGE P20029; -; . REPRODUCTION-2DPAGE IPI00319992; -; . REPRODUCTION-2DPAGE P20029; -; . UCD-2DPAGE P20029; -; . PRIDE P20029; -; . Ensembl ENSMUST00000028222; ENSMUSP00000028222; ENSMUSG00000026864; . Ensembl ENSMUST00000100171; ENSMUSP00000097747; ENSMUSG00000026864; . GeneID 14828; -; . KEGG mmu:14828; -; . CTD 3309; -; . MGI MGI:95835; Hspa5; . eggNOG COG0443; -; . GeneTree ENSGT00550000074467; -; . HOGENOM HBG334976; -; . HOVERGEN HBG051845; -; . InParanoid P20029; -; . KO K09490; -; . OMA NQLTTNP; -; . OrthoDB EOG444KJV; -; . PhylomeDB P20029; -; . Reactome REACT_89750; Hemostasis; . ArrayExpress P20029; -; . Bgee P20029; -; . CleanEx MM_HSPA5; -; . Genevestigator P20029; -; . GermOnline ENSMUSG00000026864; Mus musculus; . GO GO:0009986; C:cell surface; IDA:MGI; . GO GO:0005788; C:endoplasmic reticulum lumen; IDA:BHF-UCL; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0051787; F:misfolded protein binding; IDA:BHF-UCL; . GO GO:0043022; F:ribosome binding; IDA:MGI; . GO GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; IMP:BHF-UCL; . GO GO:0021680; P:cerebellar Purkinje cell layer development; IMP:BHF-UCL; . GO GO:0021589; P:cerebellum structural organization; IMP:BHF-UCL; . GO GO:0006983; P:ER overload response; IDA:MGI; . GO GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IGI:MGI; . GO GO:0040019; P:positive regulation of embryonic development; TAS:BHF-UCL; . GO GO:0031398; P:positive regulation of protein ubiquitination; IMP:BHF-UCL; . GO GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:BHF-UCL; . InterPro IPR018181; Heat_shock_70_CS; . InterPro IPR001023; Hsp70; . InterPro IPR013126; Hsp_70; . PANTHER PTHR19375; Hsp70; 1; . Pfam PF00012; HSP70; 1; . PRINTS PR00301; HEATSHOCK70; . PROSITE PS00014; ER_TARGET; 1; . PROSITE PS00297; HSP70_1; 1; . PROSITE PS00329; HSP70_2; 1; . PROSITE PS01036; HSP70_3; 1; . World-2DPAGE Repository (search AC)