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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: HNRPC_HUMAN World-2DPAGE Repository (0054):  HNRPC_HUMAN HNRPC_HUMAN General information about the entry View entry in simple text format Entry name HNRPC_HUMAN Primary accession number P07910 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Heterogeneous nuclear ribonucleoproteins C1/C2; Short=hnRNP C1/C2;. Gene name Name=HNRNPC Synonyms=HNRPC Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 835: pI=4.95; Mw=33539   [identification data] %COV: SPOT 835: 49 [1]. SCORE: SPOT 835: 335 [1]. SEARCH ENGINE: SPOT 835: Mascot [1]. MAPPING (identification): SPOT 835: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P07910; HNRPC_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name HNRPC_HUMAN Primary accession number P07910 Secondary accession number(s) D3DS19 D3DS22 P22628 Q53EX2 Q59FD3 Q5FWE8 Q86SF8 Q86U45 Q96HK7 Q96HM4 Q96IY5 Q9BTS3 Sequence was last modified on  June 13, 2006 (version 4) Annotations were last modified on  October 1, 2014 (version 186) Name and origin of the protein Description RecName: Full=Heterogeneous nuclear ribonucleoproteins C1/C2; Short=hnRNP C1/C2; Gene name Name=HNRNPC Synonyms=HNRPC Encoded on Name=HNRNPC; Synonyms=HNRPC Keywords 3D-structure; Acetylation; Alternative splicing; Coiled coil; Complete proteome; Direct protein sequencing; Isopeptide bond; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ribonucleoprotein; RNA-binding; Spliceosome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M29063; AAA36576.1; -; mRNA EMBL M16342; AAA52680.1; -; mRNA EMBL BX161480; CAD61934.1; -; mRNA EMBL BX247961; CAD62300.1; -; mRNA EMBL BX247992; CAD62326.1; -; mRNA EMBL AB209527; BAD92764.1; ALT_INIT; mRNA EMBL AK223517; BAD97237.1; -; mRNA EMBL CH471078; EAW66392.1; -; Genomic_DNA EMBL CH471078; EAW66393.1; -; Genomic_DNA EMBL CH471078; EAW66394.1; -; Genomic_DNA EMBL CH471078; EAW66395.1; -; Genomic_DNA EMBL CH471078; EAW66396.1; -; Genomic_DNA EMBL CH471078; EAW66399.1; -; Genomic_DNA EMBL CH471078; EAW66400.1; -; Genomic_DNA EMBL BC003394; AAH03394.1; -; mRNA EMBL BC007052; AAH07052.1; -; mRNA EMBL BC008364; AAH08364.1; -; mRNA EMBL BC008423; AAH08423.1; -; mRNA EMBL BC066932; AAH66932.1; -; mRNA EMBL BC089438; AAH89438.1; -; mRNA EMBL BC108658; AAI08659.1; -; mRNA EMBL BC103758; AAI03759.1; -; mRNA CCDS CCDS41915.1; -. [P07910-1]; . CCDS CCDS45079.1; -. [P07910-2]; . PIR A26885; A26885; . PIR C34504; C34504; . RefSeq NP_001070910.1; NM_001077442.1. [P07910-1]; . RefSeq NP_001070911.1; NM_001077443.1. [P07910-2]; . RefSeq NP_004491.2; NM_004500.3. [P07910-2]; . RefSeq NP_112604.2; NM_031314.2. [P07910-1]; . RefSeq XP_006720188.1; XM_006720125.1. [P07910-2]; . RefSeq XP_006720189.1; XM_006720126.1. [P07910-2]; . UniGene Hs.508848; -; . UniGene Hs.675546; -; . PDB 1TXP; NMR; -; A/B/C/D=194-220 PDB 1WF2; NMR; -; A=8-92 PDB 3LN4; X-ray; 1.30 A; C=102-117 PDBsum 1TXP; -; . PDBsum 1WF2; -; . PDBsum 3LN4; -; . ProteinModelPortal P07910; -; . SMR P07910; 2-92; . BioGrid 109424; 134; . DIP DIP-29854N; -; . IntAct P07910; 71; . MINT MINT-4999718; -; . ChEMBL CHEMBL2216742; -; . PhosphoSite P07910; -; . DMDM 108935845; -; . SWISS-2DPAGE P07910; -; . MaxQB P07910; -; . PaxDb P07910; -; . PRIDE P07910; -; . DNASU 3183; -; . Ensembl ENST00000420743; ENSP00000404848; ENSG00000092199. [P07910-1]; . Ensembl ENST00000430246; ENSP00000442816; ENSG00000092199. [P07910-2]; . Ensembl ENST00000449098; ENSP00000404559; ENSG00000092199. [P07910-2]; . Ensembl ENST00000553300; ENSP00000450544; ENSG00000092199. [P07910-2]; . Ensembl ENST00000554455; ENSP00000451291; ENSG00000092199. [P07910-1]; . Ensembl ENST00000554969; ENSP00000450725; ENSG00000092199. [P07910-2]; . Ensembl ENST00000555883; ENSP00000450629; ENSG00000092199. [P07910-4]; . Ensembl ENST00000556628; ENSP00000451652; ENSG00000092199. [P07910-3]; . Ensembl ENST00000556897; ENSP00000451176; ENSG00000092199. [P07910-2]; . Ensembl ENST00000557201; ENSP00000452276; ENSG00000092199. [P07910-1]; . GeneID 3183; -; . KEGG hsa:3183; -; . UCSC uc001vzw.3; human. [P07910-2]; . UCSC uc001vzy.3; human. [P07910-1]; . UCSC uc001wac.3; human. [P07910-4]; . UCSC uc001wad.3; human. [P07910-3]; . CTD 3183; -; . GeneCards GC14M021677; -; . HGNC HGNC:5035; HNRNPC; . HPA CAB005223; -; . HPA HPA051075; -; . MIM 164020; gene; . neXtProt NX_P07910; -; . PharmGKB PA162391217; -; . eggNOG NOG311712; -; . HOVERGEN HBG002302; -; . InParanoid P07910; -; . KO K12884; -; . OMA FSSPVEM; -; . OrthoDB EOG7KWSK9; -; . PhylomeDB P07910; -; . TreeFam TF330974; -; . Reactome REACT_125; Processing of Capped Intron-Containing Pre-mRNA; . Reactome REACT_467; mRNA Splicing - Major Pathway; . ChiTaRS HNRNPC; human; . EvolutionaryTrace P07910; -; . GeneWiki HNRNPC; -; . GenomeRNAi 3183; -; . NextBio 12634; -; . PRO PR:P07910; -; . ArrayExpress P07910; -; . Bgee P07910; -; . Genevestigator P07910; -; . GO GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:UniProt; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt; . GO GO:0016020; C:membrane; IDA:UniProt; . GO GO:0000790; C:nuclear chromatin; IDA:UniProt; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProt; . GO GO:0043234; C:protein complex; IDA:UniProt; . GO GO:0005681; C:spliceosomal complex; IDA:HGNC; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProt; . GO GO:0031492; F:nucleosomal DNA binding; IDA:UniProt; . GO GO:0000166; F:nucleotide binding; IEA:InterPro; . GO GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . GO GO:0008266; F:poly(U) RNA binding; IDA:UniProt; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0003723; F:RNA binding; NAS:HGNC; . GO GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProt; . GO GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProt; . GO GO:0070935; P:3'-UTR-mediated mRNA stabilization; IMP:UniProt; . GO GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt; . GO GO:0010467; P:gene expression; TAS:Reactome; . GO GO:0000398; P:mRNA splicing; via spliceosome; IC:UniProtKB GO GO:0001649; P:osteoblast differentiation; IDA:UniProt; . GO GO:0008380; P:RNA splicing; TAS:Reactome; . Gene3D 3.30.70.330; -; 1; . InterPro IPR017347; hnRNP_C_Raly; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . Pfam PF00076; RRM_1; 1; . PIRSF PIRSF037992; hnRNP-C_Raly; 1; . SMART SM00360; RRM; 1; . PROSITE PS50102; RRM; 1; . World-2DPAGE Repository (search AC)