resource logo

World-2DPAGE Repository

Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.

World-2DPAGE Repository 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]


use 'Ctrl' to select several

Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal

Exclude local DBs
has only effect if a remote
interface is selected
Searching in 'World-2DPAGE Repository [0019]' for entry matching: HPCA_MOUSE

World-2DPAGE Repository (0019):  HPCA_MOUSE


General information about the entry
View entry in simple text format
Entry nameHPCA_MOUSE
Primary accession numberP84075
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Neuron-specific calcium-binding protein hippocalcin;.
Gene nameName=Hpca
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
  map experimental info

pI=4.87; Mw=22527  [identification data]
pI=4.87; Mw=22527  [identification data]

IDENTIFICATION: SPOT 871: Peptides number=4. SeqCov=16.6%. MOWSE score=4.16E+2 [1]
SPOT 887: Peptides number=3. SeqCov=7.8%. MOWSE score=4.03E+2 [1].
MAPPING (identification):
SPOT 871: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 887: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Willard Freeman, Penn State College of Medicine, USA
UniProtKB/Swiss-ProtP84075; HPCA_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameHPCA_MOUSE
Primary accession numberP84075
Secondary accession number(s) A2A7R4 P32076 P41211 P70510
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on September 21, 2011 (version 70)
Name and origin of the protein
DescriptionRecName: Full=Neuron-specific calcium-binding protein hippocalcin;
Gene nameName=Hpca
Encoded onName=Hpca
KeywordsCalcium; Complete proteome; Lipoprotein; Myristate; Reference proteome; Repeat.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAB015200; BAA74455.1; -; Genomic_DNA
EMBLAF326551; AAL37397.1; -; mRNA
EMBLAF326552; AAL37398.1; -; mRNA
EMBLAK002992; BAB22502.1; -; mRNA
EMBLAL606977; CAM19712.1; -; Genomic_DNA
EMBLBC049607; AAH49607.1; -; mRNA
EMBLBC058588; AAH58588.1; -; mRNA
IPIIPI00230310; -; .
RefSeqNP_001123891.1; NM_001130419.1; .
RefSeqNP_034601.1; NM_010471.3; .
UniGeneMm.384452; -; .
ProteinModelPortalP84075; -; .
SMRP84075; 5-185; .
IntActP84075; 1; .
PhosphoSiteP84075; -; .
PRIDEP84075; -; .
EnsemblENSMUST00000030572; ENSMUSP00000030572; ENSMUSG00000028785; .
EnsemblENSMUST00000095807; ENSMUSP00000093486; ENSMUSG00000028785; .
EnsemblENSMUST00000116442; ENSMUSP00000112143; ENSMUSG00000028785; .
EnsemblENSMUST00000116444; ENSMUSP00000112145; ENSMUSG00000028785; .
EnsemblENSMUST00000164649; ENSMUSP00000129548; ENSMUSG00000028785; .
GeneID15444; -; .
KEGGmmu:15444; -; .
UCSCuc007ncx.1; mouse; .
CTD3208; -; .
MGIMGI:1336200; Hpca; .
GeneTreeENSGT00560000076803; -; .
HOGENOMHBG746798; -; .
HOVERGENHBG108179; -; .
InParanoidP84075; -; .
OrthoDBEOG4G1MHC; -; .
PhylomeDBP84075; -; .
NextBio288236; -; .
ArrayExpressP84075; -; .
BgeeP84075; -; .
CleanExMM_HPCA; -; .
GenevestigatorP84075; -; .
GermOnlineENSMUSG00000028785; Mus musculus; .
GOGO:0003779; F:actin binding; ISS:UniProtKB; .
GOGO:0005509; F:calcium ion binding; IEA:InterPro; .
InterProIPR018248; EF-hand; .
InterProIPR011992; EF-hand-like_dom; .
InterProIPR018247; EF_Hand_1_Ca_BS; .
InterProIPR018249; EF_HAND_2; .
InterProIPR002048; EF_hand_Ca-bd; .
InterProIPR001125; Recoverin; .
Gene3DG3DSA:; EF-Hand_type; 1; .
PfamPF00036; efhand; 3; .
SMARTSM00054; EFh; 3; .
PROSITEPS00018; EF_HAND_1; 3; .
PROSITEPS50222; EF_HAND_2; 3; .

World-2DPAGE Repository image

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server