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Searching in 'World-2DPAGE Repository [0004]' for entry matching: HPRT_RAT

World-2DPAGE Repository (0004):  HPRT_RAT


General information about the entry
View entry in simple text format
Entry nameHPRT_RAT
Primary accession numberP27605
integrated into World-2DPAGE Repository (0004) on October 13, 2008 (release 1)
2D Annotations were last modified onMay 18, 2011 (version 2)
General Annotations were last modified on December 22, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Hypoxanthine-guanine phosphoribosyltransferase; Short=HGPRT; Short=HGPRTase; EC=;.
Gene nameName=Hprt1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
  map experimental info

pI=5.89; Mw=29000  [identification data]

MAPPING (identification):
SPOT 608: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtP27605; HPRT_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameHPRT_RAT
Primary accession numberP27605
Secondary accession number(s) P70469 Q4KMC5 Q62926
Sequence was last modified on August 1, 1992 (version 1)
Annotations were last modified on November 16, 2011 (version 93)
Name and origin of the protein
DescriptionRecName: Full=Hypoxanthine-guanine phosphoribosyltransferase; Short=HGPRT; Short=HGPRTase; EC=;
Gene nameName=Hprt1
Encoded onName=Hprt1; Synonyms=Hprt
KeywordsComplete proteome; Cytoplasm; Direct protein sequencing; Glycosyltransferase; Magnesium; Metal-binding; Nucleotide-binding; Purine salvage; Reference proteome; Transferase.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLM63983; AAA41350.1; -; mRNA
EMBLS79292; AAB21288.1; -; mRNA
EMBLX62085; CAA43997.1; -; mRNA
EMBLAF001282; AAB65640.1; -; Genomic_DNA
EMBLAF001278; AAB65640.1; JOINED; Genomic_DNA
EMBLAF009655; AAB65640.1; JOINED; Genomic_DNA
EMBLAF009656; AAB65640.1; JOINED; Genomic_DNA
EMBLAF001279; AAB65640.1; JOINED; Genomic_DNA
EMBLAF001280; AAB65640.1; JOINED; Genomic_DNA
EMBLAF001281; AAB65640.1; JOINED; Genomic_DNA
EMBLBC098629; AAH98629.1; -; mRNA
EMBLU06049; AAA56887.1; -; Genomic_DNA
IPIIPI00560533; -; .
PIRS18140; S18140; .
RefSeqNP_036715.1; NM_012583.2; .
UniGeneRn.47; -; .
ProteinModelPortalP27605; -; .
SMRP27605; 5-218; .
IntActP27605; 2; .
STRINGP27605; -; .
PhosphoSiteP27605; -; .
World-2DPAGE0004:P27605; -; .
PRIDEP27605; -; .
EnsemblENSRNOT00000045153; ENSRNOP00000043388; ENSRNOG00000031367; .
GeneID24465; -; .
KEGGrno:24465; -; .
UCSCNM_012583; rat; .
CTD3251; -; .
RGD2826; Hprt1; .
eggNOGroNOG08855; -; .
HOVERGENHBG000242; -; .
InParanoidP27605; -; .
OrthoDBEOG4H72CM; -; .
PhylomeDBP27605; -; .
NextBio603395; -; .
ArrayExpressP27605; -; .
GenevestigatorP27605; -; .
GermOnlineENSRNOG00000031367; Rattus norvegicus; .
GOGO:0005829; C:cytosol; IBA:RefGenome; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0052657; F:guanine phosphoribosyltransferase activity; ISS:UniProtKB; .
GOGO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IDA:RGD; .
GOGO:0000287; F:magnesium ion binding; IBA:RefGenome; .
GOGO:0000166; F:nucleotide binding; IEA:UniProtKB-KW; .
GOGO:0006168; P:adenine salvage; IBA:RefGenome; .
GOGO:0032869; P:cellular response to insulin stimulus; IEP:RGD; .
GOGO:0021954; P:central nervous system neuron development; IBA:RefGenome; .
GOGO:0021895; P:cerebral cortex neuron differentiation; IBA:RefGenome; .
GOGO:0019835; P:cytolysis; IBA:RefGenome; .
GOGO:0048813; P:dendrite morphogenesis; IBA:RefGenome; .
GOGO:0046038; P:GMP catabolic process; ISS:UniProtKB; .
GOGO:0032263; P:GMP salvage; IBA:RefGenome; .
GOGO:0007625; P:grooming behavior; IBA:RefGenome; .
GOGO:0006178; P:guanine salvage; ISS:UniProtKB; .
GOGO:0043103; P:hypoxanthine salvage; ISS:UniProtKB; .
GOGO:0032264; P:IMP salvage; IBA:RefGenome; .
GOGO:0046651; P:lymphocyte proliferation; IBA:RefGenome; .
GOGO:0045964; P:positive regulation of dopamine metabolic process; IBA:RefGenome; .
GOGO:0006166; P:purine ribonucleoside salvage; IBA:RefGenome; .
GOGO:0001975; P:response to amphetamine; IBA:RefGenome; .
GOGO:0007283; P:spermatogenesis; IEP:RGD; .
GOGO:0021756; P:striatum development; IBA:RefGenome; .
InterProIPR005904; Hxn_phspho_trans; .
InterProIPR000836; PRibTrfase; .
KOK00760; -; .
PfamPF00156; Pribosyltran; 1; .
TIGRFAMsTIGR01203; HGPRTase; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server