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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0043]' for entry matching: HSPB1_MOUSE World-2DPAGE Repository (0043):  HSPB1_MOUSE HSPB1_MOUSE General information about the entry View entry in simple text format Entry name HSPB1_MOUSE Primary accession number P14602 integrated into World-2DPAGE Repository (0043) on  January 4, 2012 (release 1) 2D Annotations were last modified on January 6, 2012 (version 1) General Annotations were last modified on  April 18, 2012 (version 2) Name and origin of the protein Description RecName: Full=Heat shock protein beta-1; Short=HspB1; AltName: Full=Growth-related 25 kDa protein; AltName: Full=Heat shock 25 kDa protein; Short=HSP 25; AltName: Full=Heat shock 27 kDa protein; Short=HSP 27; AltName: Full=p25;. Gene name Name=Hspb1 Synonyms=Hsp25, Hsp27 Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D GEL CHARACTERIZATION DOI=10.1016/j.jprot.2012.04.001 ; Sun Z., Biela L.M., Hamilton K.L., Reardon K.F. ''Concentration-dependent effects of the soy phytoestrogen genistein on the proteome of cultured cardiomyocytes'' Journal of Proteomics 0(0):0-0 (2012) 2D PAGE maps for identified proteins How to interpret a protein MMUSCULUS_HL-1PHI_4-7 {mouse HL-1 cultured cardiomyocytes hydrophilic extraction} Mus musculus (Mouse) Tissue: Cardiac myocyte   map experimental info   MMUSCULUS_HL-1PHI_4-7 MAP LOCATIONS: BAND phi32: Mw=23057   [identification data] BAND phi63: Mw=23057   [identification data] BAND phi65: Mw=23057   [identification data] %COV: BAND phi32: 17.6 [1] BAND phi63: 17.3 [1]; BAND phi65: 27.6 [1]. GENEID: BAND phi32: HSPB1_MOUSE [1] BAND phi63: HSPB1_MOUSE [1]; BAND phi65: HSPB1_MOUSE [1]. SCORE: BAND phi32: 1071 [1] BAND phi63: 273 [1]; BAND phi65: 187 [1]. SEARCH ENGINE: BAND phi32: Mascot [1] BAND phi63: Mascot [1]; BAND phi65: Mascot [1]. MAPPING (identification): BAND phi32: Tandem mass spectrometry [1]; BAND phi63: Tandem mass spectrometry [1]; BAND phi65: Tandem mass spectrometry [1]. MMUSCULUS_HL-1PHO_4-7 {mouse HL-1 cultured cardiomyocytes hydrophobic extraction} Mus musculus (Mouse) Tissue: Cardiac myocyte   map experimental info   MMUSCULUS_HL-1PHO_4-7 MAP LOCATIONS: BAND pho32: Mw=23057   [identification data] %COV: BAND pho32: 10 [1]. GENEID: BAND pho32: HSPB1_MOUSE [1]. SCORE: BAND pho32: 86 [1]. SEARCH ENGINE: BAND pho32: Mascot [1]. MAPPING (identification): BAND pho32: Tandem mass spectrometry [1]. Copyright Data from Dr. Zeyu Sun, Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, USA Cross-references IPI 00128522. UniProtKB/Swiss-Prot P14602; HSPB1_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2012_03 Entry name HSPB1_MOUSE Primary accession number P14602 Sequence was last modified on  June 1, 1994 (version 3) Annotations were last modified on  March 21, 2012 (version 127) Name and origin of the protein Description RecName: Full=Heat shock protein beta-1; Short=HspB1; AltName: Full=Growth-related 25 kDa protein; AltName: Full=Heat shock 25 kDa protein; Short=HSP 25; AltName: Full=Heat shock 27 kDa protein; Short=HSP 27; AltName: Full=p25; Gene name Name=Hspb1 Synonyms=Hsp25, Hsp27 Encoded on Name=Hspb1; Synonyms=Hsp25, Hsp27 Keywords Acetylation; Alternative splicing; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome; Stress response. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X14687; CAA32818.1; -; mRNA EMBL X14686; CAB37341.1; -; mRNA EMBL L11609; AAA37862.1; -; Genomic_DNA EMBL L11608; AAA37862.1; JOINED; Genomic_DNA EMBL L07577; AAA37861.1; -; Genomic_DNA EMBL U03560; AAA18335.1; -; mRNA EMBL U03561; AAA18336.1; -; mRNA EMBL U03562; AAA18337.1; -; mRNA EMBL BC018257; AAH18257.1; -; mRNA IPI IPI00128522; -; . IPI IPI00468068; -; . IPI IPI00623819; -; . PIR A53423; A53423; . PIR I49763; JN0679; . PIR S02143; S02143; . RefSeq NP_038588.2; NM_013560.2; . UniGene Mm.13849; -; . ProteinModelPortal P14602; -; . SMR P14602; 17-198; . DisProt DP00142; -; . IntAct P14602; 6; . STRING P14602; -; . PhosphoSite P14602; -; . SWISS-2DPAGE P14602; -; . REPRODUCTION-2DPAGE IPI00128522; -; . REPRODUCTION-2DPAGE IPI00468068; -; . REPRODUCTION-2DPAGE P14602; -; . UCD-2DPAGE P14602; -; . PRIDE P14602; -; . Ensembl ENSMUST00000005077; ENSMUSP00000005077; ENSMUSG00000004951; . Ensembl ENSMUST00000111156; ENSMUSP00000106786; ENSMUSG00000004951; . GeneID 15507; -; . KEGG mmu:15507; -; . CTD 3315; -; . MGI MGI:96240; Hspb1; . eggNOG NOG307785; -; . GeneTree ENSGT00550000074302; -; . HOGENOM HBG748242; -; . HOVERGEN HBG054766; -; . InParanoid P14602; -; . KO K04455; -; . OMA VTFEARA; -; . OrthoDB EOG4DR9DF; -; . PhylomeDB P14602; -; . NextBio 288412; -; . ArrayExpress P14602; -; . Bgee P14602; -; . CleanEx MM_HSPB1; -; . Genevestigator P14602; -; . GermOnline ENSMUSG00000004951; Mus musculus; . GO GO:0009986; C:cell surface; ISS:BHF-UCL; . GO GO:0005626; C:insoluble fraction; IDA:MGI; . GO GO:0005634; C:nucleus; IDA:MGI; . GO GO:0005886; C:plasma membrane; IDA:MGI; . GO GO:0000502; C:proteasome complex; ISS:BHF-UCL; . GO GO:0005625; C:soluble fraction; IDA:MGI; . GO GO:0005819; C:spindle; IEA:UniProtKB-SubCell; . GO GO:0030018; C:Z disc; IDA:MGI; . GO GO:0005080; F:protein kinase C binding; IDA:BHF-UCL; . GO GO:0008426; F:protein kinase C inhibitor activity; IDA:BHF-UCL; . GO GO:0043130; F:ubiquitin binding; ISS:BHF-UCL; . GO GO:0043066; P:negative regulation of apoptotic process; IDA:BHF-UCL; . GO GO:0032731; P:positive regulation of interleukin-1 beta production; IDA:BHF-UCL; . GO GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:BHF-UCL; . GO GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL; . GO GO:0006986; P:response to unfolded protein; NAS:BHF-UCL; . GO GO:0009615; P:response to virus; ISS:BHF-UCL; . InterPro IPR001436; Alpha-crystallin/HSP; . InterPro IPR002068; Hsp20; . InterPro IPR008978; HSP20-like_chaperone; . Pfam PF00011; HSP20; 1; . PIRSF PIRSF036514; Sm_HSP_B1; 1; . PRINTS PR00299; ACRYSTALLIN; . SUPFAM SSF49764; HSP20_chap; 1; . PROSITE PS01031; HSP20; 1; . World-2DPAGE Repository (search AC)