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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: LEG1_HUMAN World-2DPAGE Repository (0054):  LEG1_HUMAN LEG1_HUMAN General information about the entry View entry in simple text format Entry name LEG1_HUMAN Primary accession number P09382 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Galectin-1; Short=Gal-1; AltName: Full=14 kDa laminin-binding protein; Short=HLBP14; AltName: Full=14 kDa lectin; AltName: Full=Beta-galactoside-binding lectin L-14-I; AltName: Full=Galaptin; AltName: Full=HBL; AltName: Full=HPL; AltName: Full=Lactose-binding lectin 1; AltName: Full=Lectin galactoside-binding soluble 1; AltName: Full=Putative MAPK-activating protein PM12; AltName: Full=S-Lac lectin 1;. Gene name Name=LGALS1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 1316: pI=5.30; Mw=14585   [identification data] %COV: SPOT 1316: 82 [1]. SCORE: SPOT 1316: 501 [1]. SEARCH ENGINE: SPOT 1316: Mascot [1]. MAPPING (identification): SPOT 1316: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P09382; LEG1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name LEG1_HUMAN Primary accession number P09382 Secondary accession number(s) B2R5E8 Q9UDK5 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  October 1, 2014 (version 181) Name and origin of the protein Description RecName: Full=Galectin-1; Short=Gal-1; AltName: Full=14 kDa laminin-binding protein; Short=HLBP14; AltName: Full=14 kDa lectin; AltName: Full=Beta-galactoside-binding lectin L-14-I; AltName: Full=Galaptin; AltName: Full=HBL; AltName: Full=HPL; AltName: Full=Lactose-binding lectin 1; AltName: Full=Lectin galactoside-binding soluble 1; AltName: Full=Putative MAPK-activating protein PM12; AltName: Full=S-Lac lectin 1; Gene name Name=LGALS1 Encoded on Name=LGALS1 Keywords 3D-structure; Acetylation; Apoptosis; Complete proteome; Direct protein sequencing; Extracellular matrix; Lectin; Reference proteome; Secreted. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X14829; CAA32938.1; -; mRNA EMBL J04456; AAA36170.1; -; mRNA EMBL X15256; CAA33328.1; -; mRNA EMBL EU363770; ACA58297.1; -; mRNA EMBL M57678; AAB00777.1; -; Genomic_DNA EMBL AB097036; BAC77389.1; -; mRNA EMBL CR456511; CAG30397.1; -; mRNA EMBL AK312161; BAG35095.1; -; mRNA EMBL BT006775; AAP35421.1; -; mRNA EMBL Z83844; CAB42897.1; -; Genomic_DNA EMBL CH471095; EAW60178.1; -; Genomic_DNA EMBL BC001693; AAH01693.1; -; mRNA EMBL BC020675; AAH20675.1; -; mRNA CCDS CCDS13954.1; -; . PIR A37134; LNHUGB; . RefSeq NP_002296.1; NM_002305.3; . UniGene Hs.445351; -; . PDB 1GZW; X-ray; 1.70 A; A/B=2-135 PDB 1W6M; X-ray; 2.30 A; A/B=2-135 PDB 1W6N; X-ray; 1.65 A; A/B=2-135 PDB 1W6O; X-ray; 1.90 A; A/B=2-135 PDB 1W6P; X-ray; 1.80 A; A/B=2-135 PDB 1W6Q; X-ray; 2.10 A; A/B=2-135 PDB 2KM2; NMR; -; A/B=2-135 PDB 2ZKN; X-ray; 1.86 A; A/B=2-135 PDB 3OY8; X-ray; 2.19 A; A/B=2-135 PDB 3OYW; X-ray; 2.50 A; A/B=2-135 PDB 3T2T; X-ray; 1.90 A; A/B=1-135 PDB 3W58; X-ray; 1.58 A; A/B/C/D=2-135 PDB 3W59; X-ray; 2.10 A; A/B/C/D=2-135 PDBsum 1GZW; -; . PDBsum 1W6M; -; . PDBsum 1W6N; -; . PDBsum 1W6O; -; . PDBsum 1W6P; -; . PDBsum 1W6Q; -; . PDBsum 2KM2; -; . PDBsum 2ZKN; -; . PDBsum 3OY8; -; . PDBsum 3OYW; -; . PDBsum 3T2T; -; . PDBsum 3W58; -; . PDBsum 3W59; -; . ProteinModelPortal P09382; -; . SMR P09382; 2-135; . BioGrid 110147; 39; . DIP DIP-46153N; -; . IntAct P09382; 9; . MINT MINT-3306493; -; . STRING 9606.ENSP00000215909; -; . BindingDB P09382; -; . ChEMBL CHEMBL4915; -; . PhosphoSite P09382; -; . DMDM 126155; -; . DOSAC-COBS-2DPAGE P09382; -; . REPRODUCTION-2DPAGE IPI00219219; -; . REPRODUCTION-2DPAGE P09382; -; . SWISS-2DPAGE P09382; -; . UCD-2DPAGE P09382; -; . MaxQB P09382; -; . PaxDb P09382; -; . PeptideAtlas P09382; -; . PRIDE P09382; -; . DNASU 3956; -; . Ensembl ENST00000215909; ENSP00000215909; ENSG00000100097; . GeneID 3956; -; . KEGG hsa:3956; -; . UCSC uc003atn.3; human; . CTD 3956; -; . GeneCards GC22P038071; -; . HGNC HGNC:6561; LGALS1; . HPA CAB002157; -; . HPA HPA000646; -; . HPA HPA000687; -; . HPA HPA001130; -; . MIM 150570; gene; . neXtProt NX_P09382; -; . PharmGKB PA30337; -; . eggNOG NOG279327; -; . HOGENOM HOG000059539; -; . HOVERGEN HBG006255; -; . InParanoid P09382; -; . KO K06830; -; . OMA GHEFKFP; -; . OrthoDB EOG7NKKN0; -; . PhylomeDB P09382; -; . TreeFam TF315551; -; . ChiTaRS LGALS1; human; . EvolutionaryTrace P09382; -; . GeneWiki Galectin-1; -; . GeneWiki LGALS1; -; . GenomeRNAi 3956; -; . NextBio 15523; -; . PMAP-CutDB P09382; -; . PRO PR:P09382; -; . ArrayExpress P09382; -; . Bgee P09382; -; . CleanEx HS_LGALS1; -; . Genevestigator P09382; -; . GO GO:0009986; C:cell surface; IEA:Ensembl; . GO GO:0005737; C:cytoplasm; TAS:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:BHF-UCL; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt; . GO GO:0005622; C:intracellular; IDA:LIFEdb; . GO GO:0005634; C:nucleus; IEA:Ensembl; . GO GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell; . GO GO:0016936; F:galactoside binding; IEA:InterPro; . GO GO:0030395; F:lactose binding; IEA:Ensembl; . GO GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:IntAct; . GO GO:0004871; F:signal transducer activity; IMP:UniProtKB; . GO GO:0006915; P:apoptotic process; TAS:ProtInc; . GO GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl; . GO GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl; . GO GO:0033555; P:multicellular organismal response to stress; IEA:Ensembl; . GO GO:0045445; P:myoblast differentiation; IEA:Ensembl; . GO GO:0010812; P:negative regulation of cell-substrate adhesion; IEA:Ensembl; . GO GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl; . GO GO:0002317; P:plasma cell differentiation; IEA:Ensembl; . GO GO:0034120; P:positive regulation of erythrocyte aggregation; IEA:Ensembl; . GO GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB; . GO GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB; . GO GO:0048678; P:response to axon injury; IEA:Ensembl; . GO GO:0042493; P:response to drug; IEA:Ensembl; . GO GO:0007165; P:signal transduction; IMP:GOC; . GO GO:0031295; P:T cell costimulation; IEA:Ensembl; . Gene3D 2.60.120.200; -; 1; . InterPro IPR008985; ConA-like_lec_gl_sf; . InterPro IPR013320; ConA-like_subgrp; . InterPro IPR015535; Galectin_1; . InterPro IPR001079; Galectin_CRD; . PANTHER PTHR11346:SF30; PTHR11346:SF30; 1; . Pfam PF00337; Gal-bind_lectin; 1; . SMART SM00908; Gal-bind_lectin; 1; . SMART SM00276; GLECT; 1; . SUPFAM SSF49899; SSF49899; 1; . PROSITE PS51304; GALECTIN; 1; . World-2DPAGE Repository (search AC)