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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: MIC60_HUMAN World-2DPAGE Repository (0054):  MIC60_HUMAN MIC60_HUMAN General information about the entry View entry in simple text format Entry name MIC60_HUMAN Primary accession number Q16891 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=MICOS complex subunit MIC60; AltName: Full=Cell proliferation-inducing gene 4/52 protein; AltName: Full=Mitochondrial inner membrane protein; AltName: Full=Mitofilin; AltName: Full=p87/89; Flags: Precursor;. Gene name Name=IMMT Synonyms=HMP, MIC60, MINOS2 ORFNames=PIG4, PIG52 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 445: pI=6.08; Mw=83678   [identification data] %COV: SPOT 445: 37 [1]. SCORE: SPOT 445: 438 [1]. SEARCH ENGINE: SPOT 445: Mascot [1]. MAPPING (identification): SPOT 445: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot Q16891; MIC60_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name MIC60_HUMAN Primary accession number Q16891 Secondary accession number(s) B1H0U5 B2R5N6 Q14539 Q15092 Q68D41 Q69HW5 Q6IBL0 Q7Z3X1 Q8TAJ5 Q9P0V2 Sequence was last modified on  November 1, 1996 (version 1) Annotations were last modified on  October 1, 2014 (version 131) Name and origin of the protein Description RecName: Full=MICOS complex subunit MIC60; AltName: Full=Cell proliferation-inducing gene 4/52 protein; AltName: Full=Mitochondrial inner membrane protein; AltName: Full=Mitofilin; AltName: Full=p87/89; Flags: Precursor; Gene name Name=IMMT Synonyms=HMP, MIC60, MINOS2 ORFNames=PIG4, PIG52 Encoded on Name=IMMT; Synonyms=HMP, MIC60, MINOS2; ORFNames=PIG4, PIG52 Keywords Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Polymorphism; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL D21091; BAA04653.1; -; mRNA EMBL D21092; BAA04654.1; -; mRNA EMBL D21093; BAA04655.1; -; mRNA EMBL D21094; BAA04656.1; -; mRNA EMBL L42572; AAA85336.1; -; mRNA EMBL CR456793; CAG33074.1; -; mRNA EMBL AK312251; BAG35183.1; -; mRNA EMBL AY232292; AAP69987.1; -; mRNA EMBL AY921637; AAX10024.1; -; mRNA EMBL BX537369; CAD97612.1; -; mRNA EMBL CR749590; CAH18389.1; ALT_TERM; mRNA EMBL BC002412; AAH02412.1; -; mRNA EMBL BC027458; AAH27458.1; -; mRNA EMBL AF148646; AAF73126.1; -; mRNA CCDS CCDS46355.1; -. [Q16891-1]; . CCDS CCDS46356.1; -. [Q16891-4]; . CCDS CCDS46357.1; -. [Q16891-2]; . RefSeq NP_001093639.1; NM_001100169.1. [Q16891-4]; . RefSeq NP_001093640.1; NM_001100170.1. [Q16891-2]; . RefSeq NP_006830.2; NM_006839.2. [Q16891-1]; . RefSeq XP_005264170.1; XM_005264113.1. [Q16891-3]; . UniGene Hs.148559; -; . ProteinModelPortal Q16891; -; . BioGrid 116185; 88; . DIP DIP-32517N; -; . IntAct Q16891; 69; . MINT MINT-1034498; -; . PhosphoSite Q16891; -; . DMDM 29427676; -; . REPRODUCTION-2DPAGE IPI00554469; -; . REPRODUCTION-2DPAGE Q16891; -; . MaxQB Q16891; -; . PaxDb Q16891; -; . PRIDE Q16891; -; . DNASU 10989; -; . Ensembl ENST00000410111; ENSP00000387262; ENSG00000132305. [Q16891-1]; . Ensembl ENST00000442664; ENSP00000407788; ENSG00000132305. [Q16891-4]; . Ensembl ENST00000449247; ENSP00000396899; ENSG00000132305. [Q16891-2]; . GeneID 10989; -; . KEGG hsa:10989; -; . UCSC uc002sqy.4; human. [Q16891-1]; . UCSC uc002srb.4; human. [Q16891-2]; . CTD 10989; -; . GeneCards GC02M086282; -; . HGNC HGNC:6047; IMMT; . HPA CAB022439; -; . HPA HPA036164; -; . HPA HPA036165; -; . MIM 600378; gene; . neXtProt NX_Q16891; -; . PharmGKB PA29858; -; . eggNOG NOG307662; -; . HOVERGEN HBG039233; -; . InParanoid Q16891; -; . KO K17785; -; . OMA QKQKGDT; -; . PhylomeDB Q16891; -; . TreeFam TF312832; -; . ChiTaRS IMMT; human; . GeneWiki IMMT; -; . GenomeRNAi 10989; -; . NextBio 41751; -; . PRO PR:Q16891; -; . ArrayExpress Q16891; -; . Bgee Q16891; -; . Genevestigator Q16891; -; . GO GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IDA:UniProt; . GO GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0051560; P:mitochondrial calcium ion homeostasis; IEA:Ensembl; . GO GO:0009409; P:response to cold; IEA:Ensembl; . InterPro IPR019133; Mt-IM_prot_Mitofilin; . Pfam PF09731; Mitofilin; 1; . World-2DPAGE Repository (search AC)