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Searching in 'World-2DPAGE Repository [0019]' for entry matching: O35964




World-2DPAGE Repository (0019):  O35964


O35964


General information about the entry
View entry in simple text format
Entry nameSH3G1_RAT
Primary accession numberO35964
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Endophilin-A2; AltName: Full=Endophilin-2; AltName: Full=SH3 domain protein 2B; AltName: Full=SH3 domain-containing GRB2-like protein 1; AltName: Full=SH3p8;.
Gene nameName=Sh3gl1
Synonyms=Sh3p8
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info
 
HIPP_SYNAP

MAP LOCATIONS:
pI=5.45; Mw=41694  [identification data]

IDENTIFICATION: SPOT 496: Peptides number=6. SeqCov=14.4%. MOWSE score=1.40E+5 [1].
MAPPING (identification):
SPOT 496: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtO35964; SH3G1_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameSH3G1_RAT
Primary accession numberO35964
Sequence was last modified on January 1, 1998 (version 1)
Annotations were last modified on November 16, 2011 (version 83)
Name and origin of the protein
DescriptionRecName: Full=Endophilin-A2; AltName: Full=Endophilin-2; AltName: Full=SH3 domain protein 2B; AltName: Full=SH3 domain-containing GRB2-like protein 1; AltName: Full=SH3p8;
Gene nameName=Sh3gl1
Synonyms=Sh3p8
Encoded onName=Sh3gl1; Synonyms=Sh3p8
Keywords3D-structure; Coiled coil; Complete proteome; Cytoplasm; Endocytosis; Endosome; Lipid-binding; Membrane; Phosphoprotein; Reference proteome; SH3 domain.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF009602; AAC14882.1; -; mRNA
EMBLAB008161; BAA22921.1; -; mRNA
EMBLBC070893; AAH70893.1; -; mRNA
IPIIPI00214192; -; .
RefSeqNP_112518.1; NM_031239.2; .
UniGeneRn.8762; -; .
PDB3C0C; X-ray; 1.70 A; A=303-368
PDBsum3C0C; -; .
ProteinModelPortalO35964; -; .
SMRO35964; 9-247; 305-368; .
IntActO35964; 3; .
PRIDEO35964; -; .
GeneID81922; -; .
KEGGrno:81922; -; .
CTD6455; -; .
RGD708456; Sh3gl1; .
HOVERGENHBG052866; -; .
NextBio615817; -; .
GenevestigatorO35964; -; .
GOGO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell; .
GOGO:0005626; C:insoluble fraction; IDA:RGD; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0051020; F:GTPase binding; IPI:RGD; .
GOGO:0008289; F:lipid binding; IEA:UniProtKB-KW; .
GOGO:0019902; F:phosphatase binding; IPI:RGD; .
GOGO:0006897; P:endocytosis; IEA:UniProtKB-KW; .
InterProIPR004148; BAR; .
InterProIPR001452; SH3_domain; .
KOK11247; -; .
PfamPF03114; BAR; 1; .
PfamPF00018; SH3_1; 1; .
PRINTSPR00452; SH3DOMAIN; .
SMARTSM00721; BAR; 1; .
SMARTSM00326; SH3; 1; .
SUPFAMSSF50044; SH3; 1; .
PROSITEPS51021; BAR; 1; .
PROSITEPS50002; SH3; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server