World-2DPAGE Repository

RecName: Full=Endophilin-A2; AltName: Full=Endophilin-2; AltName: Full=SH3 domain protein 2B; AltName: Full=SH3 domain-containing GRB2-like protein 1; AltName: Full=SH3p8;.

Gene name

Name=Sh3gl1
Synonyms=Sh3p8

Annotated species

Rattus norvegicus (Rat) [TaxID: 10116]

Taxonomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	2D-PAGE GEL CHARACTERIZATION DOI=10.1111/j.1471-4159.2010.06719.x; VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M. ''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome'' J of Neurochemistry 113(6):1577-1588 (2010)

2D PAGE maps for identified proteins

How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus

map experimental info

HIPP_SYNAP

MAP LOCATIONS:

SPOT 496:

pI=5.45; Mw=41694

[identification data]

IDENTIFICATION: SPOT 496: Peptides number=6. SeqCov=14.4%. MOWSE score=1.40E+5 [1].
MAPPING (identification):

SPOT 496: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Willard Freeman, Penn State College of Medicine, USA

Cross-references

UniProtKB/Swiss-Prot

O35964; SH3G1_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	SH3G1_RAT
Primary accession number	O35964
Sequence was last modified on	January 1, 1998 (version 1)
Annotations were last modified on	November 16, 2011 (version 83)
Name and origin of the protein
Description	RecName: Full=Endophilin-A2; AltName: Full=Endophilin-2; AltName: Full=SH3 domain protein 2B; AltName: Full=SH3 domain-containing GRB2-like protein 1; AltName: Full=SH3p8;
Gene name	Name=Sh3gl1 Synonyms=Sh3p8
Encoded on	Name=Sh3gl1; Synonyms=Sh3p8
Keywords	3D-structure; Coiled coil; Complete proteome; Cytoplasm; Endocytosis; Endosome; Lipid-binding; Membrane; Phosphoprotein; Reference proteome; SH3 domain.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	AF009602; AAC14882.1; -; mRNA
EMBL	AB008161; BAA22921.1; -; mRNA
EMBL	BC070893; AAH70893.1; -; mRNA
IPI	IPI00214192; -; .
RefSeq	NP_112518.1; NM_031239.2; .
UniGene	Rn.8762; -; .
PDB	3C0C; X-ray; 1.70 A; A=303-368
PDBsum	3C0C; -; .
ProteinModelPortal	O35964; -; .
SMR	O35964; 9-247; 305-368; .
IntAct	O35964; 3; .
PRIDE	O35964; -; .
GeneID	81922; -; .
KEGG	rno:81922; -; .
CTD	6455; -; .
RGD	708456; Sh3gl1; .
HOVERGEN	HBG052866; -; .
NextBio	615817; -; .
Genevestigator	O35964; -; .
GO	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell; .
GO	GO:0005626; C:insoluble fraction; IDA:RGD; .
GO	GO:0005625; C:soluble fraction; IDA:RGD; .
GO	GO:0051020; F:GTPase binding; IPI:RGD; .
GO	GO:0008289; F:lipid binding; IEA:UniProtKB-KW; .
GO	GO:0019902; F:phosphatase binding; IPI:RGD; .
GO	GO:0006897; P:endocytosis; IEA:UniProtKB-KW; .
InterPro	IPR004148; BAR; .
InterPro	IPR001452; SH3_domain; .
KO	K11247; -; .
Pfam	PF03114; BAR; 1; .
Pfam	PF00018; SH3_1; 1; .
PRINTS	PR00452; SH3DOMAIN; .
SMART	SM00721; BAR; 1; .
SMART	SM00326; SH3; 1; .
SUPFAM	SSF50044; SH3; 1; .
PROSITE	PS51021; BAR; 1; .
PROSITE	PS50002; SH3; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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