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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: ODO1_RAT World-2DPAGE Repository (0022):  ODO1_RAT ODO1_RAT General information about the entry View entry in simple text format Entry name ODO1_RAT Primary accession number Q5XI78 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=2-oxoglutarate dehydrogenase, mitochondrial; EC=1.2.4.2; AltName: Full=2-oxoglutarate dehydrogenase complex component E1; Short=OGDC-E1; AltName: Full=Alpha-ketoglutarate dehydrogenase; Flags: Precursor;. Gene name Name=Ogdh Synonyms=Ogdhl Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 70: pI=6.30; Mw=117419   [identification data] SPOT 291: pI=6.30; Mw=117419   [identification data] SPOT 516: pI=6.30; Mw=117419   [identification data] SPOT 532: pI=6.30; Mw=117419   [identification data] SPOT 657: pI=6.30; Mw=117419   [identification data] SPOT 903: pI=6.30; Mw=117419   [identification data] SPOT 925: pI=6.30; Mw=117419   [identification data] IDENTIFICATION: SPOT 70: SeqCov=16.4%. Peptides MS=18/20. Mascot PMF Score=141 [1] SPOT 291: SeqCov=9.5%. Peptides MS=10/20. Mascot PMF Score=41 [1]; SPOT 516: SeqCov=13.5%. Peptides MS=14/20. Mascot PMF Score=83 [1]; SPOT 532: SeqCov=16.5%. Peptides MS=17/20. Mascot PMF Score=126 [1]; SPOT 657: SeqCov=11.1%. Peptides MS=10/20. Mascot PMF Score=48 [1]; SPOT 903: SeqCov=12.1%. Peptides MS=10/20. Mascot PMF Score=52 [1]; SPOT 925: SeqCov=13.9%. Peptides MS=13/20. Mascot PMF Score=87 [1]. PEPTIDE EVIDENCE: SPOT 291: 264-FEEFLQR-270 (15) / 500-DVVVDLVCYR-509 (34) / 185-VFHLPTTTFIGGQEPALPLR-204 (40) [1] SPOT 516: 264-FEEFLQR-270 (24) [1]; SPOT 657: 75-SWDIFFR-81 (48) / 930-IEQLSPFPFDLLLK-943 (40) / 583-HWLDSPWPGFFTLDGQPR-600 (39) [1]; SPOT 903: 75-SWDIFFR-81 (26) / 583-HWLDSPWPGFFTLDGQPR-600 (20) / 185-VFHLPTTTFIGGQEPALPLR-204 (18) [1]; SPOT 925: 75-SWDIFFR-81 (38) [1]. MAPPING (identification): SPOT 70: Peptide mass fingerprinting [1]; SPOT 291: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 516: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 532: Peptide mass fingerprinting [1]; SPOT 657: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 903: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 925: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot Q5XI78; ODO1_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name ODO1_RAT Primary accession number Q5XI78 Sequence was last modified on  November 23, 2004 (version 1) Annotations were last modified on  November 16, 2011 (version 59) Name and origin of the protein Description RecName: Full=2-oxoglutarate dehydrogenase, mitochondrial; EC=1.2.4.2; AltName: Full=2-oxoglutarate dehydrogenase complex component E1; Short=OGDC-E1; AltName: Full=Alpha-ketoglutarate dehydrogenase; Flags: Precursor; Gene name Name=Ogdh Synonyms=Ogdhl Encoded on Name=Ogdh; Synonyms=Ogdhl Keywords Acetylation; Complete proteome; Direct protein sequencing; Glycolysis; Isopeptide bond; Mitochondrion; Oxidoreductase; Reference proteome; Thiamine pyrophosphate; Transit peptide; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL BC083811; AAH83811.1; -; mRNA IPI IPI00215093; -; . RefSeq NP_001017461.1; NM_001017461.1; . UniGene Rn.45991; -; . ProteinModelPortal Q5XI78; -; . STRING Q5XI78; -; . World-2DPAGE 0004:Q5XI78; -; . PRIDE Q5XI78; -; . Ensembl ENSRNOT00000057199; ENSRNOP00000054026; ENSRNOG00000005130; . GeneID 360975; -; . KEGG rno:360975; -; . NMPDR fig|10116.3.peg.10710; -; . UCSC NM_001017461; rat; . CTD 4967; -; . RGD 1561359; Ogdh; . eggNOG roNOG15522; -; . GeneTree ENSGT00530000063092; -; . HOVERGEN HBG001892; -; . PhylomeDB Q5XI78; -; . NextBio 674779; -; . ArrayExpress Q5XI78; -; . Genevestigator Q5XI78; -; . GO GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; . GO GO:0031966; C:mitochondrial membrane; ISS:UniProtKB; . GO GO:0045252; C:oxoglutarate dehydrogenase complex; IDA:RGD; . GO GO:0051087; F:chaperone binding; IPI:RGD; . GO GO:0031072; F:heat shock protein binding; IPI:RGD; . GO GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB; . GO GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro; . GO GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD; . GO GO:0006096; P:glycolysis; IEA:UniProtKB-KW; . GO GO:0006734; P:NADH metabolic process; IDA:RGD; . GO GO:0006104; P:succinyl-CoA metabolic process; IDA:RGD; . GO GO:0006099; P:tricarboxylic acid cycle; IDA:RGD; . InterPro IPR011603; 2oxoglutarate_DH_E1; . InterPro IPR001017; DH_E1; . InterPro IPR005475; Transketolase-like_Pyr-bd; . KO K00164; -; . PANTHER PTHR23152; 2oxoglutarate_DH_E1; 1; . Pfam PF00676; E1_dh; 1; . Pfam PF02779; Transket_pyr; 1; . PIRSF PIRSF000157; Oxoglu_dh_E1; 1; . SMART SM00861; Transket_pyr; 1; . TIGRFAMs TIGR00239; 2oxo_dh_E1; 1; . World-2DPAGE Repository (search AC)