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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0021]' for entry matching: OTC_MOUSE World-2DPAGE Repository (0021):  OTC_MOUSE OTC_MOUSE General information about the entry View entry in simple text format Entry name OTC_MOUSE Primary accession number P11725 integrated into World-2DPAGE Repository (0021) on  June 9, 2010 (release 1) 2D Annotations were last modified on June 20, 2011 (version 2) General Annotations were last modified on  November 30, 2011 (version 2) Name and origin of the protein Description RecName: Full=Ornithine carbamoyltransferase, mitochondrial; EC=2.1.3.3; AltName: Full=Ornithine transcarbamylase; Short=OTCase; Flags: Precursor;. Gene name Name=Otc Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D-PAGE GEL CHARACTERIZATION De Cegli R., Romito A., Iacobacci S., Mao L., Lauria M., Fedele A.O., Klose J., Borel C., Descombes P., Antonarakis S.E., Di Bernardo D., Banfi S., Ballabio A., Cobellis G. ''A mouse Embryonic Stem Cell Bank for inducible overexpression of human Chromosome 21 genes'' Genome Biol 11(6):R64 (2010) 2D PAGE maps for identified proteins How to interpret a protein RUNX1_DAY7 {Mouse embryonic stem cells overexpressing Runx1, Day 7} Mus musculus (Mouse) Tissue: Embryonic stem cell   map experimental info   RUNX1_DAY7 MAP LOCATIONS: SPOT 2314: pI=8.96; Mw=39800   [identification data] EXPRESSION: SPOT 2314: Protein ratio 48h/0h=2.28 [1]. IDENTIFICATION: SPOT 2314: Mascot Protein score=41. SeqCov=2%. Peptides identified=2 [1]. MAPPING (identification): SPOT 2314: Tandem mass spectrometry [1]. Copyright Data from Dr. Lei Mao, Institute of Human Genetics, Charite Universitaetsmedizin Berlin, Germany Cross-references UniProtKB/Swiss-Prot P11725; OTC_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name OTC_MOUSE Primary accession number P11725 Sequence was last modified on  October 1, 1989 (version 1) Annotations were last modified on  November 16, 2011 (version 114) Name and origin of the protein Description RecName: Full=Ornithine carbamoyltransferase, mitochondrial; EC=2.1.3.3; AltName: Full=Ornithine transcarbamylase; Short=OTCase; Flags: Precursor; Gene name Name=Otc Encoded on Name=Otc Keywords Acetylation; Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome; Disease mutation; Mitochondrion; Reference proteome; Transferase; Transit peptide; Urea cycle. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M17030; AAA39865.1; -; mRNA EMBL M12716; AAA39864.1; ALT_SEQ; Genomic_DNA EMBL X07092; CAA30121.1; -; Genomic_DNA EMBL X07093; CAA30121.1; JOINED; Genomic_DNA EMBL X07094; CAA30121.1; JOINED; Genomic_DNA EMBL X07095; CAA30121.1; JOINED; Genomic_DNA EMBL X07096; CAA30121.1; JOINED; Genomic_DNA EMBL X07097; CAA30121.1; JOINED; Genomic_DNA EMBL X07098; CAA30121.1; JOINED; Genomic_DNA EMBL X07099; CAA30121.1; JOINED; Genomic_DNA EMBL X07100; CAA30121.1; JOINED; Genomic_DNA IPI IPI00116603; -; . PIR A43609; OWMS; . RefSeq NP_032795.1; NM_008769.3; . UniGene Mm.2611; -; . ProteinModelPortal P11725; -; . SMR P11725; 34-354; . STRING P11725; -; . PhosphoSite P11725; -; . SWISS-2DPAGE P11725; -; . PRIDE P11725; -; . Ensembl ENSMUST00000049910; ENSMUSP00000056152; ENSMUSG00000031173; . GeneID 18416; -; . KEGG mmu:18416; -; . CTD 5009; -; . MGI MGI:97448; Otc; . eggNOG roNOG05084; -; . HOGENOM HBG579429; -; . HOVERGEN HBG007881; -; . InParanoid P11725; -; . OMA KHLLSIK; -; . OrthoDB EOG4GB76C; -; . PhylomeDB P11725; -; . NextBio 294052; -; . ArrayExpress P11725; -; . Bgee P11725; -; . CleanEx MM_OTC; -; . Genevestigator P11725; -; . GermOnline ENSMUSG00000031173; Mus musculus; . GO GO:0005743; C:mitochondrial inner membrane; IDA:MGI; . GO GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; . GO GO:0009348; C:ornithine carbamoyltransferase complex; IEA:InterPro; . GO GO:0004585; F:ornithine carbamoyltransferase activity; IEA:EC; . GO GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW; . GO GO:0000050; P:urea cycle; IEA:UniProtKB-KW; . InterPro IPR006132; Asp/Orn_carbamoyltranf_P-bd; . InterPro IPR006130; Asp/Orn_carbamoylTrfase; . InterPro IPR006131; Asp_carbamoyltransf_Asp/Orn-bd; . InterPro IPR002292; Orn_carbamltrans; . KO K00611; -; . Pfam PF00185; OTCace; 1; . Pfam PF02729; OTCace_N; 1; . PRINTS PR00100; AOTCASE; . PRINTS PR00102; OTCASE; . SUPFAM SSF53671; Asp/Orn_carbamoyltranf; 1; . TIGRFAMs TIGR00658; Orni_carb_tr; 1; . PROSITE PS00097; CARBAMOYLTRANSFERASE; 1; . World-2DPAGE Repository (search AC)