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World-2DPAGE Repository

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Searching in 'World-2DPAGE Repository [0014]' for entry matching: P01946

World-2DPAGE Repository (0014):  P01946


General information about the entry
View entry in simple text format
Entry nameHBA_RAT
Primary accession numberP01946
integrated into World-2DPAGE Repository (0014) on October 13, 2008 (release 1)
2D Annotations were last modified onJune 1, 2011 (version 3)
General Annotations were last modified on November 25, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Hemoglobin subunit alpha-1/2; AltName: Full=Alpha-1/2-globin; AltName: Full=Hemoglobin alpha-1/2 chain;.
Gene nameName=Hba1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
  map experimental info

pI=8.34; Mw=9000  [identification data]

IDENTIFICATION: SPOT 3324: SeqCov=79%. MascotPMF=86 [1].
MAPPING (identification):
SPOT 3324: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtP01946; HBA_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameHBA_RAT
Primary accession numberP01946
Secondary accession number(s) P33583 Q63243 Q80XV2 Q91V15
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 105)
Name and origin of the protein
DescriptionRecName: Full=Hemoglobin subunit alpha-1/2; AltName: Full=Alpha-1/2-globin; AltName: Full=Hemoglobin alpha-1/2 chain;
Gene nameName=Hba1
Encoded onName=Hba1; Synonyms=Hba-a1
Keywords3D-structure; Complete proteome; Direct protein sequencing; Heme; Iron; Metal-binding; Oxygen transport; Polymorphism; Reference proteome; Transport.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLM17083; AAA41308.1; -; mRNA
EMBLX56325; CAA39764.1; -; Genomic_DNA
EMBLX65495; CAA46476.1; -; Genomic_DNA
EMBLU29528; AAA99054.1; -; Genomic_DNA
EMBLBC059150; AAH59150.1; -; mRNA
EMBLBC091567; AAH91567.1; -; mRNA
EMBLS66657; AAP13984.1; -; Genomic_DNA
EMBLM32510; AAA41315.1; -; mRNA
IPIIPI00287835; -; .
PIRI54239; HART1; .
RefSeqNP_001007723.1; NM_001007722.1; .
RefSeqNP_037228.1; NM_013096.1; .
UniGeneRn.107334; -; .
UniGeneRn.203003; -; .
PDB3DHT; X-ray; 2.98 A; A=2-142
PDB3HF4; X-ray; 2.70 A; A/E=2-142
PDBsum3DHT; -; .
PDBsum3HF4; -; .
ProteinModelPortalP01946; -; .
SMRP01946; 2-142; .
IntActP01946; 1; .
STRINGP01946; -; .
PhosphoSiteP01946; -; .
Rat-heart-2DPAGEP01946; -; .
PRIDEP01946; -; .
EnsemblENSRNOT00000048977; ENSRNOP00000044081; ENSRNOG00000031686; .
EnsemblENSRNOT00000051483; ENSRNOP00000044233; ENSRNOG00000029886; .
GeneID25632; -; .
GeneID360504; -; .
KEGGrno:25632; -; .
KEGGrno:360504; -; .
UCSCNM_013096; rat; .
CTD110257; -; .
RGD2782; Hba-a1; .
eggNOGroNOG16000; -; .
GeneTreeENSGT00550000074190; -; .
HOVERGENHBG009709; -; .
InParanoidP01946; -; .
OrthoDBEOG47M209; -; .
PhylomeDBP01946; -; .
NextBio607439; -; .
GenevestigatorP01946; -; .
GermOnlineENSRNOG00000029886; Rattus norvegicus; .
GOGO:0005833; C:hemoglobin complex; IDA:RGD; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0001540; F:beta-amyloid binding; IDA:RGD; .
GOGO:0020037; F:heme binding; IDA:RGD; .
GOGO:0043177; F:organic acid binding; IPI:RGD; .
GOGO:0019825; F:oxygen binding; IEA:InterPro; .
GOGO:0005344; F:oxygen transporter activity; IC:RGD; .
GOGO:0045776; P:negative regulation of blood pressure; IMP:RGD; .
GOGO:0051291; P:protein heterooligomerization; IDA:RGD; .
GOGO:0051930; P:regulation of sensory perception of pain; IMP:RGD; .
InterProIPR009050; Globin-like; .
InterProIPR012292; Globin_dom; .
InterProIPR000971; Globin_subset; .
InterProIPR002338; Haemoglobin_a; .
InterProIPR018331; Haemoglobin_alpha_chain; .
InterProIPR002339; Haemoglobin_pi; .
Gene3DG3DSA:1.10.490.10; Globin_related; 1; .
KOK13822; -; .
PANTHERPTHR11442:SF14; Pi_haem; 1; .
PfamPF00042; Globin; 1; .
SUPFAMSSF46458; Globin_like; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server