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World-2DPAGE Repository
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Searching in 'World-2DPAGE Repository [0014]' for entry
matching:
P01946
World-2DPAGE Repository
(0014):
P01946
P01946
General information about the entry
View entry in simple text format
Entry name
HBA_RAT
Primary accession number
P01946
integrated into World-2DPAGE Repository (0014) on
October 13, 2008 (release 1)
2D Annotations were last modified on
June 1, 2011 (version 3)
General Annotations were last modified on
November 25, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Hemoglobin subunit alpha-1/2; AltName: Full=Alpha-1/2-globin; AltName: Full=Hemoglobin alpha-1/2 chain;.
Gene name
Name=Hba1
Synonyms=Hba-a1
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1002/pmic.200900680
;
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein
RAT_CEREBELLUM_21D
{Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
map experimental info
RAT_CEREBELLUM_21D
MAP LOCATIONS:
SPOT 3324
:
pI=8.34; Mw=9000
[identification data]
IDENTIFICATION:
SPOT 3324: SeqCov=79%. MascotPMF=86 [
1
].
MAPPING (identification):
SPOT
3324
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
PRIDE
10017.
UniProtKB/Swiss-Prot
P01946; HBA_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_11
Entry name
HBA_RAT
Primary accession number
P01946
Secondary accession number(s)
P33583 Q63243 Q80XV2 Q91V15
Sequence was last modified on
January 23, 2007 (version 3)
Annotations were last modified on
November 16, 2011 (version 105)
Name and origin of the protein
Description
RecName: Full=Hemoglobin subunit alpha-1/2; AltName: Full=Alpha-1/2-globin; AltName: Full=Hemoglobin alpha-1/2 chain;
Gene name
Name=Hba1
Synonyms=Hba-a1
Encoded on
Name=Hba1; Synonyms=Hba-a1
Keywords
3D-structure
;
Complete proteome
;
Direct protein sequencing
;
Heme
;
Iron
;
Metal-binding
;
Oxygen transport
;
Polymorphism
;
Reference proteome
;
Transport
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
M17083; AAA41308.1
; -; mRNA
EMBL
X56325; CAA39764.1
; -; Genomic_DNA
EMBL
X65495; CAA46476.1
; -; Genomic_DNA
EMBL
U29528; AAA99054.1
; -; Genomic_DNA
EMBL
BC059150; AAH59150.1
; -; mRNA
EMBL
BC091567; AAH91567.1
; -; mRNA
EMBL
S66657; AAP13984.1
; -; Genomic_DNA
EMBL
M32510; AAA41315.1
; -; mRNA
IPI
IPI00287835; -
; .
PIR
I54239; HART1
; .
RefSeq
NP_001007723.1; NM_001007722.1
; .
RefSeq
NP_037228.1; NM_013096.1
; .
UniGene
Rn.107334; -
; .
UniGene
Rn.203003; -
; .
PDB
3DHT; X-ray
; 2.98 A; A=2-142
PDB
3HF4; X-ray
; 2.70 A; A/E=2-142
PDBsum
3DHT; -
; .
PDBsum
3HF4; -
; .
ProteinModelPortal
P01946; -
; .
SMR
P01946; 2-142
; .
IntAct
P01946; 1
; .
STRING
P01946; -
; .
PhosphoSite
P01946; -
; .
Rat-heart-2DPAGE
P01946; -
; .
PRIDE
P01946; -
; .
Ensembl
ENSRNOT00000048977; ENSRNOP00000044081
; ENSRNOG00000031686; .
Ensembl
ENSRNOT00000051483; ENSRNOP00000044233
; ENSRNOG00000029886; .
GeneID
25632; -
; .
GeneID
360504; -
; .
KEGG
rno:25632; -
; .
KEGG
rno:360504; -
; .
UCSC
NM_013096; rat
; .
CTD
110257; -
; .
RGD
2782; Hba-a1
; .
eggNOG
roNOG16000; -
; .
GeneTree
ENSGT00550000074190; -
; .
HOVERGEN
HBG009709; -
; .
InParanoid
P01946; -
; .
OMA
HIDELTG; -
; .
OrthoDB
EOG47M209; -
; .
PhylomeDB
P01946; -
; .
NextBio
607439; -
; .
Genevestigator
P01946; -
; .
GermOnline
ENSRNOG00000029886; Rattus norvegicus
; .
GO
GO:0005833; C:hemoglobin complex
; IDA:RGD; .
GO
GO:0005625; C:soluble fraction
; IDA:RGD; .
GO
GO:0001540; F:beta-amyloid binding
; IDA:RGD; .
GO
GO:0020037; F:heme binding
; IDA:RGD; .
GO
GO:0043177; F:organic acid binding
; IPI:RGD; .
GO
GO:0019825; F:oxygen binding
; IEA:InterPro; .
GO
GO:0005344; F:oxygen transporter activity
; IC:RGD; .
GO
GO:0045776; P:negative regulation of blood pressure
; IMP:RGD; .
GO
GO:0051291; P:protein heterooligomerization
; IDA:RGD; .
GO
GO:0051930; P:regulation of sensory perception of pain
; IMP:RGD; .
InterPro
IPR009050; Globin-like
; .
InterPro
IPR012292; Globin_dom
; .
InterPro
IPR000971; Globin_subset
; .
InterPro
IPR002338; Haemoglobin_a
; .
InterPro
IPR018331; Haemoglobin_alpha_chain
; .
InterPro
IPR002339; Haemoglobin_pi
; .
Gene3D
G3DSA:1.10.490.10; Globin_related
; 1; .
KO
K13822; -
; .
PANTHER
PTHR11442:SF14; Pi_haem
; 1; .
Pfam
PF00042; Globin
; 1; .
PRINTS
PR00612; ALPHAHAEM
; .
PRINTS
PR00815; PIHAEM
; .
SUPFAM
SSF46458; Globin_like
; 1; .
PROSITE
PS01033; GLOBIN
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
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, using the
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ver. 3.10.2
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