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Searching in 'World-2DPAGE Repository [0022]' for entry matching: P04276




World-2DPAGE Repository (0022):  P04276


P04276


General information about the entry
View entry in simple text format
Entry nameVTDB_RAT
Primary accession numberP04276
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Vitamin D-binding protein; Short=DBP; Short=VDB; AltName: Full=Gc-globulin; AltName: Full=Group-specific component; Flags: Precursor;.
Gene nameName=Gc
Synonyms=Dbp
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info
 
HCR_LCR_HEART

MAP LOCATIONS:
pI=5.65; Mw=55106  [identification data]

IDENTIFICATION: SPOT 28: SeqCov=27.1%. Peptides MS=9/20. Mascot PMF Score=64 [1].
PEPTIDE EVIDENCE: SPOT 28: 42-SLSLILYSR-50 (40) / 243-VPTANLEDVLPLAEDLTEILSR-264 (103) / 66-EVVSLTEECCAEGADPNCYDTR-87 (88) [1].
MAPPING (identification):
SPOT 28: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtP04276; VTDB_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameVTDB_RAT
Primary accession numberP04276
Sequence was last modified on May 1, 1992 (version 3)
Annotations were last modified on November 16, 2011 (version 99)
Name and origin of the protein
DescriptionRecName: Full=Vitamin D-binding protein; Short=DBP; Short=VDB; AltName: Full=Gc-globulin; AltName: Full=Group-specific component; Flags: Precursor;
Gene nameName=Gc
Synonyms=Dbp
Encoded onName=Gc; Synonyms=Dbp
KeywordsActin-binding; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Reference proteome; Repeat; Secreted; Signal; Transport; Vitamin D.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM12450; AAA41080.1; -; mRNA
EMBLJ05148; AAA41082.1; -; mRNA
EMBLM60205; AAA41081.1; -; Genomic_DNA
EMBLM60197; AAA41081.1; JOINED; Genomic_DNA
EMBLM60198; AAA41081.1; JOINED; Genomic_DNA
EMBLM60199; AAA41081.1; JOINED; Genomic_DNA
EMBLM60200; AAA41081.1; JOINED; Genomic_DNA
EMBLM60201; AAA41081.1; JOINED; Genomic_DNA
EMBLM60202; AAA41081.1; JOINED; Genomic_DNA
EMBLM60203; AAA41081.1; JOINED; Genomic_DNA
EMBLM60204; AAA41081.1; JOINED; Genomic_DNA
IPIIPI00194097; -; .
PIRA38726; VYRTD; .
RefSeqNP_036696.1; NM_012564.2; .
UniGeneRn.1437; -; .
ProteinModelPortalP04276; -; .
SMRP04276; 20-474; .
STRINGP04276; -; .
PRIDEP04276; -; .
GeneID24384; -; .
KEGGrno:24384; -; .
UCSCNM_012564; rat; .
CTD2638; -; .
RGD2667; Gc; .
eggNOGroNOG09498; -; .
HOVERGENHBG009729; -; .
InParanoidP04276; -; .
OrthoDBEOG4MKNG5; -; .
NextBio603153; -; .
ArrayExpressP04276; -; .
GenevestigatorP04276; -; .
GermOnlineENSRNOG00000003119; Rattus norvegicus; .
GOGO:0030424; C:axon; IDA:RGD; .
GOGO:0005829; C:cytosol; IDA:RGD; .
GOGO:0005615; C:extracellular space; IDA:RGD; .
GOGO:0048471; C:perinuclear region of cytoplasm; IDA:RGD; .
GOGO:0003779; F:actin binding; ISS:UniProtKB; .
GOGO:0005499; F:vitamin D binding; IDA:RGD; .
GOGO:0051183; F:vitamin transporter activity; IEA:InterPro; .
GOGO:0007565; P:female pregnancy; IEP:RGD; .
GOGO:0007595; P:lactation; IEP:RGD; .
GOGO:0032355; P:response to estradiol stimulus; IEP:RGD; .
GOGO:0031667; P:response to nutrient levels; IEP:RGD; .
InterProIPR000264; Serum_albumin; .
InterProIPR020858; Serum_albumin-like; .
InterProIPR020857; Serum_albumin_CS; .
InterProIPR014760; Serum_albumin_N; .
InterProIPR000213; VitD-bd; .
InterProIPR015247; VitD-bind_III; .
KOK12258; -; .
PfamPF00273; Serum_albumin; 2; .
PfamPF09164; VitD-bind_III; 1; .
PRINTSPR00802; SERUMALBUMIN; .
PRINTSPR00804; VITAMNDBNDNG; .
SMARTSM00103; ALBUMIN; 2; .
SUPFAMSSF48552; Serum_albumin; 3; .
PROSITEPS00212; ALBUMIN_1; 1; .
PROSITEPS51438; ALBUMIN_2; 2; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server