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World-2DPAGE Repository
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World-2DPAGE Portal
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Searching in 'World-2DPAGE Repository [0019]' for entry
matching:
P07335
World-2DPAGE Repository
(0019):
P07335
P07335
General information about the entry
View entry in simple text format
Entry name
KCRB_RAT
Primary accession number
P07335
integrated into World-2DPAGE Repository (0019) on
December 9, 2009 (release 1)
2D Annotations were last modified on
May 30, 2011 (version 2)
General Annotations were last modified on
January 13, 2012 (version 2)
Name and origin of the protein
Description
RecName: Full=Creatine kinase B-type; EC=2.7.3.2; AltName: Full=B-CK; AltName: Full=Creatine kinase B chain;.
Gene name
Name=Ckb
Synonyms=Ckbb
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1111/j.1471-4159.2010.06719.x
;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein
HIPP_SYNAP
{Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
map experimental info
HIPP_SYNAP
MAP LOCATIONS:
SPOT 531
:
pI=5.32; Mw=40883
[identification data]
SPOT 535
:
pI=5.40; Mw=45561
[identification data]
SPOT 1117
:
pI=5.32; Mw=40883
[identification data]
SPOT 1174
:
pI=5.33; Mw=42984
[identification data]
IDENTIFICATION:
SPOT 531: Peptides number=5. SeqCov=21.3%. MOWSE score=2.40E+6 [
1
]
SPOT 535: Peptides number=13. SeqCov=55.6%. MOWSE score=1.02E+16 [
1
]; SPOT 1117: Peptides number=6. SeqCov=23.9%. MOWSE score=7.85E+6 [
1
]; SPOT 1174: Peptides number=13. SeqCov=45.9%. MOWSE score=5.86E+10 [
1
].
MAPPING (identification):
SPOT
531
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
];
SPOT
535
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
];
SPOT
1117
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
];
SPOT
1174
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-Prot
P07335; KCRB_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_12
Entry name
KCRB_RAT
Primary accession number
P07335
Secondary accession number(s)
A0JPK7 Q499P7 Q5PPJ5 Q6IRE0 Q6P139
Sequence was last modified on
January 9, 2007 (version 2)
Annotations were last modified on
November 16, 2011 (version 102)
Name and origin of the protein
Description
RecName: Full=Creatine kinase B-type; EC=2.7.3.2; AltName: Full=B-CK; AltName: Full=Creatine kinase B chain;
Gene name
Name=Ckb
Synonyms=Ckbb
Encoded on
Name=Ckb; Synonyms=Ckbb
Keywords
ATP-binding
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Kinase
;
Nucleotide-binding
;
Phosphoprotein
;
Reference proteome
;
Transferase
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
M14400; AAA40930.1
; -; mRNA
EMBL
M18668; AAA40932.1
; -; Genomic_DNA
EMBL
M57664; AAA40933.1
; -; mRNA
EMBL
M57665; AAA40931.1
; -; Genomic_DNA
EMBL
BC065307; AAH65307.2
; -; mRNA
EMBL
BC070955; AAH70955.2
; -; mRNA
EMBL
BC087656; AAH87656.1
; ALT_INIT; mRNA
EMBL
BC099814; AAH99814.2
; -; mRNA
EMBL
BC127477; AAI27478.2
; -; mRNA
IPI
IPI00470288; -
; .
PIR
A23980; KIRTCB
; .
RefSeq
NP_036661.2; NM_012529.2
; .
UniGene
Rn.1472; -
; .
ProteinModelPortal
P07335; -
; .
SMR
P07335; 2-381
; .
STRING
P07335; -
; .
PhosphoSite
P07335; -
; .
World-2DPAGE
0004:P07335; -
; .
PRIDE
P07335; -
; .
Ensembl
ENSRNOT00000015122; ENSRNOP00000015122
; ENSRNOG00000010872; .
GeneID
24264; -
; .
KEGG
rno:24264; -
; .
UCSC
NM_012529; rat
; .
CTD
1152; -
; .
RGD
2357; Ckb
; .
eggNOG
roNOG15359; -
; .
GeneTree
ENSGT00550000074561; -
; .
HOVERGEN
HBG001339; -
; .
InParanoid
P07335; -
; .
OrthoDB
EOG4R7V9X; -
; .
NextBio
602815; -
; .
ArrayExpress
P07335; -
; .
Genevestigator
P07335; -
; .
GermOnline
ENSRNOG00000010872; Rattus norvegicus
; .
GO
GO:0005886; C:plasma membrane
; TAS:RGD; .
GO
GO:0005524; F:ATP binding
; IEA:UniProtKB-KW; .
GO
GO:0004111; F:creatine kinase activity
; TAS:RGD; .
GO
GO:0005515; F:protein binding
; IPI:RGD; .
GO
GO:0007420; P:brain development
; IEP:RGD; .
GO
GO:0030644; P:cellular chloride ion homeostasis
; IMP:RGD; .
GO
GO:0006603; P:phosphocreatine metabolic process
; TAS:RGD; .
InterPro
IPR000749; ATP-guanido_PTrfase
; .
InterPro
IPR022415; ATP-guanido_PTrfase_AS
; .
InterPro
IPR022414; ATP-guanido_PTrfase_cat
; .
InterPro
IPR022413; ATP-guanido_PTrfase_N
; .
InterPro
IPR014746; Gln_synth/guanido_kin_cat_dom
; .
Gene3D
G3DSA:1.10.135.10; ATP-gua_Ptrans
; 1; .
Gene3D
G3DSA:3.30.590.10; ATP-gua_Ptrans
; 1; .
KO
K00933; -
; .
PANTHER
PTHR11547; ATP-gua_Ptrans
; 1; .
Pfam
PF00217; ATP-gua_Ptrans
; 1; .
Pfam
PF02807; ATP-gua_PtransN
; 1; .
SUPFAM
SSF48034; ATP-gua_Ptrans
; 1; .
PROSITE
PS00112; PHOSPHAGEN_KINASE
; 1; .
PROSITE
PS51510; PHOSPHAGEN_KINASE_C
; 1; .
PROSITE
PS51509; PHOSPHAGEN_KINASE_N
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server