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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: P09211 World-2DPAGE Repository (0054):  P09211 P09211 General information about the entry View entry in simple text format Entry name GSTP1_HUMAN Primary accession number P09211 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Glutathione S-transferase P; EC=2.5.1.18; AltName: Full=GST class-pi; AltName: Full=GSTP1-1;. Gene name Name=GSTP1 Synonyms=FAEES3, GST3 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 1097: pI=9.73; Mw=22876   [identification data] %COV: SPOT 1097: 70 [1]. SCORE: SPOT 1097: 595 [1]. SEARCH ENGINE: SPOT 1097: Mascot [1]. MAPPING (identification): SPOT 1097: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P09211; GSTP1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GSTP1_HUMAN Primary accession number P09211 Secondary accession number(s) O00460 Q15690 Q5TZY3 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  October 1, 2014 (version 177) Name and origin of the protein Description RecName: Full=Glutathione S-transferase P; EC=2.5.1.18; AltName: Full=GST class-pi; AltName: Full=GSTP1-1; Gene name Name=GSTP1 Synonyms=FAEES3, GST3 Encoded on Name=GSTP1; Synonyms=FAEES3, GST3 Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Mitochondrion; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transferase. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X06547; CAA29794.1; -; mRNA EMBL M24485; AAA56823.1; -; Genomic_DNA EMBL X08058; CAA30847.1; -; Genomic_DNA EMBL X08094; CAA30894.1; -; Genomic_DNA EMBL X08095; CAA30894.1; JOINED; Genomic_DNA EMBL X08096; CAA30894.1; JOINED; Genomic_DNA EMBL X15480; CAA33508.1; -; mRNA EMBL U12472; AAA64919.1; -; Genomic_DNA EMBL U30897; AAC51280.1; -; mRNA EMBL U62589; AAC51237.1; -; mRNA EMBL U21689; AAC13869.1; -; Genomic_DNA EMBL BT019949; AAV38752.1; -; mRNA EMBL BT019950; AAV38753.1; -; mRNA EMBL CR450361; CAG29357.1; -; mRNA EMBL AY324387; AAP72967.1; -; Genomic_DNA EMBL BC010915; AAH10915.1; -; mRNA CCDS CCDS41679.1; -; . PIR A41177; A41177; . PIR JS0153; A37378; . RefSeq NP_000843.1; NM_000852.3; . UniGene Hs.523836; -; . PDB 10GS; X-ray; 2.20 A; A/B=2-210 PDB 11GS; X-ray; 2.30 A; A/B=1-210 PDB 12GS; X-ray; 2.10 A; A/B=1-210 PDB 13GS; X-ray; 1.90 A; A/B=1-210 PDB 14GS; X-ray; 2.80 A; A/B=1-210 PDB 16GS; X-ray; 1.90 A; A/B=1-210 PDB 17GS; X-ray; 1.90 A; A/B=1-210 PDB 18GS; X-ray; 1.90 A; A/B=1-210 PDB 19GS; X-ray; 1.90 A; A/B=2-210 PDB 1AQV; X-ray; 1.94 A; A/B=2-210 PDB 1AQW; X-ray; 1.80 A; A/B/C/D=2-210 PDB 1AQX; X-ray; 2.00 A; A/B/C/D=2-210 PDB 1EOG; X-ray; 2.10 A; A/B=3-210 PDB 1EOH; X-ray; 2.50 A; A/B/C/D/E/F/G/H=2-210 PDB 1GSS; X-ray; 2.80 A; A/B=2-210 PDB 1KBN; X-ray; 2.00 A; A/B=2-210 PDB 1LBK; X-ray; 1.86 A; A/B=2-203 PDB 1MD3; X-ray; 2.03 A; A/B=2-210 PDB 1MD4; X-ray; 2.10 A; A/B=2-210 PDB 1PGT; X-ray; 1.80 A; A/B=1-210 PDB 1PX6; X-ray; 2.10 A; A/B=2-210 PDB 1PX7; X-ray; 2.03 A; A/B=2-210 PDB 1ZGN; X-ray; 2.10 A; A/B=2-210 PDB 20GS; X-ray; 2.45 A; A/B=2-210 PDB 22GS; X-ray; 1.90 A; A/B=1-210 PDB 2A2R; X-ray; 1.40 A; A/B=1-210 PDB 2A2S; X-ray; 1.70 A; A/B=1-210 PDB 2GSS; X-ray; 1.90 A; A/B=2-210 PDB 2J9H; X-ray; 2.40 A; A/B=2-210 PDB 2PGT; X-ray; 1.90 A; A/B=1-210 PDB 3CSH; X-ray; 1.55 A; A/B=2-210 PDB 3CSI; X-ray; 1.90 A; A/B/C/D=2-210 PDB 3CSJ; X-ray; 1.90 A; A/B=2-210 PDB 3DD3; X-ray; 2.25 A; A/B=1-210 PDB 3DGQ; X-ray; 1.60 A; A/B=1-210 PDB 3GSS; X-ray; 1.90 A; A/B=2-210 PDB 3GUS; X-ray; 1.53 A; A/B=2-210 PDB 3HJM; X-ray; 2.10 A; A/B/C/D=2-210 PDB 3HJO; X-ray; 1.95 A; A/B=2-210 PDB 3HKR; X-ray; 1.80 A; A/B=2-210 PDB 3IE3; X-ray; 1.80 A; A/B=2-210 PDB 3KM6; X-ray; 2.10 A; A/B=2-210 PDB 3KMN; X-ray; 1.80 A; A/B=2-210 PDB 3KMO; X-ray; 2.60 A; A/B=2-210 PDB 3N9J; X-ray; 1.85 A; A/B=1-210 PDB 3PGT; X-ray; 2.14 A; A/B=1-210 PDB 4GSS; X-ray; 2.50 A; A/B=2-210 PDB 4PGT; X-ray; 2.10 A; A/B=1-210 PDB 5GSS; X-ray; 1.95 A; A/B=2-210 PDB 6GSS; X-ray; 1.90 A; A/B=2-210 PDB 7GSS; X-ray; 2.20 A; A/B=2-210 PDB 8GSS; X-ray; 1.90 A; A/B/C=2-210 PDB 9GSS; X-ray; 1.97 A; A/B=2-210 PDBsum 10GS; -; . PDBsum 11GS; -; . PDBsum 12GS; -; . PDBsum 13GS; -; . PDBsum 14GS; -; . PDBsum 16GS; -; . PDBsum 17GS; -; . PDBsum 18GS; -; . PDBsum 19GS; -; . PDBsum 1AQV; -; . PDBsum 1AQW; -; . PDBsum 1AQX; -; . PDBsum 1EOG; -; . PDBsum 1EOH; -; . PDBsum 1GSS; -; . PDBsum 1KBN; -; . PDBsum 1LBK; -; . PDBsum 1MD3; -; . PDBsum 1MD4; -; . PDBsum 1PGT; -; . PDBsum 1PX6; -; . PDBsum 1PX7; -; . PDBsum 1ZGN; -; . PDBsum 20GS; -; . PDBsum 22GS; -; . PDBsum 2A2R; -; . PDBsum 2A2S; -; . PDBsum 2GSS; -; . PDBsum 2J9H; -; . PDBsum 2PGT; -; . PDBsum 3CSH; -; . PDBsum 3CSI; -; . PDBsum 3CSJ; -; . PDBsum 3DD3; -; . PDBsum 3DGQ; -; . PDBsum 3GSS; -; . PDBsum 3GUS; -; . PDBsum 3HJM; -; . PDBsum 3HJO; -; . PDBsum 3HKR; -; . PDBsum 3IE3; -; . PDBsum 3KM6; -; . PDBsum 3KMN; -; . PDBsum 3KMO; -; . PDBsum 3N9J; -; . PDBsum 3PGT; -; . PDBsum 4GSS; -; . PDBsum 4PGT; -; . PDBsum 5GSS; -; . PDBsum 6GSS; -; . PDBsum 7GSS; -; . PDBsum 8GSS; -; . PDBsum 9GSS; -; . ProteinModelPortal P09211; -; . SMR P09211; 1-210; . BioGrid 109205; 27; . IntAct P09211; 25; . MINT MINT-4998983; -; . STRING 9606.ENSP00000381607; -; . BindingDB P09211; -; . ChEMBL CHEMBL3902; -; . DrugBank DB00903; Ethacrynic acid; . DrugBank DB00143; Glutathione; . PhosphoSite P09211; -; . DOSAC-COBS-2DPAGE P09211; -; . OGP P09211; -; . REPRODUCTION-2DPAGE IPI00219757; -; . SWISS-2DPAGE P09211; -; . UCD-2DPAGE P09211; -; . MaxQB P09211; -; . PaxDb P09211; -; . PRIDE P09211; -; . DNASU 2950; -; . Ensembl ENST00000398606; ENSP00000381607; ENSG00000084207; . GeneID 2950; -; . KEGG hsa:2950; -; . UCSC uc001omf.3; human; . CTD 2950; -; . GeneCards GC11P067351; -; . HGNC HGNC:4638; GSTP1; . HPA CAB019298; -; . HPA HPA019779; -; . HPA HPA019869; -; . MIM 134660; gene; . neXtProt NX_P09211; -; . PharmGKB PA29028; -; . eggNOG KOG1695; -; . HOGENOM HOG000115733; -; . HOVERGEN HBG108324; -; . InParanoid P09211; -; . KO K00799; -; . OMA ANSIYIV; -; . OrthoDB EOG7KH9M3; -; . PhylomeDB P09211; -; . TreeFam TF105321; -; . Reactome REACT_172715; Detoxification of Reactive Oxygen Species; . Reactome REACT_6926; Glutathione conjugation; . SABIO-RK P09211; -; . ChiTaRS GSTP1; human; . EvolutionaryTrace P09211; -; . GeneWiki GSTP1; -; . GenomeRNAi 2950; -; . NextBio 11692; -; . PMAP-CutDB P09211; -; . PRO PR:P09211; -; . ArrayExpress P09211; -; . Bgee P09211; -; . CleanEx HS_GSTP1; -; . Genevestigator P09211; -; . GO GO:0005737; C:cytoplasm; TAS:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005615; C:extracellular space; IDA:UniProt; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt; . GO GO:0005622; C:intracellular; IDA:BHF-UCL; . GO GO:0005739; C:mitochondrion; IDA:HPA; . GO GO:0005634; C:nucleus; IEA:UniProtKB-SubCell; . GO GO:0005886; C:plasma membrane; IDA:HPA; . GO GO:0097057; C:TRAF2-GSTP1 complex; IDA:BHF-UCL; . GO GO:0031982; C:vesicle; IDA:UniProtKB; . GO GO:0035731; F:dinitrosyl-iron complex binding; IDA:BHF-UCL; . GO GO:0004364; F:glutathione transferase activity; IDA:UniProtKB; . GO GO:0008432; F:JUN kinase binding; ISS:BHF-UCL; . GO GO:0019207; F:kinase regulator activity; ISS:BHF-UCL; . GO GO:0070026; F:nitric oxide binding; NAS:BHF-UCL; . GO GO:0005515; F:protein binding; IPI:IntAct; . GO GO:0035730; F:S-nitrosoglutathione binding; IDA:BHF-UCL; . GO GO:0071222; P:cellular response to lipopolysaccharide; ISS:BHF-UCL; . GO GO:0007417; P:central nervous system development; TAS:ProtInc; . GO GO:0035726; P:common myeloid progenitor cell proliferation; ISS:BHF-UCL; . GO GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome; . GO GO:0006749; P:glutathione metabolic process; IDA:UniProtKB; . GO GO:0002674; P:negative regulation of acute inflammatory response; NAS:BHF-UCL; . GO GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB; . GO GO:0009890; P:negative regulation of biosynthetic process; IDA:BHF-UCL; . GO GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL; . GO GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:BHF-UCL; . GO GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL; . GO GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; ISS:BHF-UCL; . GO GO:0032691; P:negative regulation of interleukin-1 beta production; IDA:BHF-UCL; . GO GO:0043508; P:negative regulation of JUN kinase activity; IDA:BHF-UCL; . GO GO:0070664; P:negative regulation of leukocyte proliferation; ISS:BHF-UCL; . GO GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL; . GO GO:0043409; P:negative regulation of MAPK cascade; NAS:BHF-UCL; . GO GO:0071638; P:negative regulation of monocyte chemotactic protein-1 production; IDA:BHF-UCL; . GO GO:0051771; P:negative regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL; . GO GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL; . GO GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:BHF-UCL; . GO GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:BHF-UCL; . GO GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IC:BHF-UCL; . GO GO:0035732; P:nitric oxide storage; NAS:BHF-UCL; . GO GO:0032930; P:positive regulation of superoxide anion generation; ISS:BHF-UCL; . GO GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL; . GO GO:0032872; P:regulation of stress-activated MAPK cascade; ISS:BHF-UCL; . GO GO:0000302; P:response to reactive oxygen species; ISS:BHF-UCL; . GO GO:0044281; P:small molecule metabolic process; TAS:Reactome; . GO GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB; . Gene3D 1.20.1050.10; -; 1; . Gene3D 3.40.30.10; -; 1; . InterPro IPR010987; Glutathione-S-Trfase_C-like; . InterPro IPR004045; Glutathione_S-Trfase_N; . InterPro IPR004046; GST_C; . InterPro IPR003082; GST_pi; . InterPro IPR012336; Thioredoxin-like_fold; . Pfam PF00043; GST_C; 1; . Pfam PF02798; GST_N; 1; . PRINTS PR01268; GSTRNSFRASEP; . SUPFAM SSF47616; SSF47616; 1; . SUPFAM SSF52833; SSF52833; 1; . PROSITE PS50405; GST_CTER; 1; . PROSITE PS50404; GST_NTER; 1; . World-2DPAGE Repository (search AC)