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Searching in 'World-2DPAGE Repository [0030]' for entry matching: P09527

World-2DPAGE Repository (0030):  P09527


General information about the entry
View entry in simple text format
Entry nameRAB7A_RAT
Primary accession numberP09527
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Ras-related protein Rab-7a; AltName: Full=Ras-related protein BRL-RAS; AltName: Full=Ras-related protein p23;.
Gene nameName=Rab7a
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
  map experimental info

pI=4.87; Mw=27072  [identification data]

IDENTIFICATION: SPOT 2176: Mascot protein score=131. Number of peptides=2 [1].
MAPPING (identification):
SPOT 2176: Tandem mass spectrometry [1].

Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
UniProtKB/Swiss-ProtP09527; RAB7A_RAT.
World-2DPAGE RepositoryP09527; RAB7A_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameRAB7A_RAT
Primary accession numberP09527
Secondary accession number(s) Q4AEF6
Sequence was last modified on October 1, 1996 (version 2)
Annotations were last modified on November 16, 2011 (version 110)
Name and origin of the protein
DescriptionRecName: Full=Ras-related protein Rab-7a; AltName: Full=Ras-related protein BRL-RAS; AltName: Full=Ras-related protein p23;
Gene nameName=Rab7a
Encoded onName=Rab7a; Synonyms=Rab7
Keywords3D-structure; Complete proteome; Cytoplasmic vesicle; Endosome; GTP-binding; Lipoprotein; Lysosome; Methylation; Nucleotide-binding; Phosphoprotein; Prenylation; Protein transport; Reference proteome; Transport.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX12535; CAA31053.1; -; mRNA
EMBLAF286535; AAG00543.1; -; mRNA
EMBLAB158427; BAE16999.1; -; mRNA
EMBLAB158428; BAE17000.1; -; mRNA
EMBLBC072470; AAH72470.1; -; mRNA
IPIIPI00215564; -; .
PIRS01934; S01934; .
RefSeqNP_076440.1; NM_023950.3; .
UniGeneRn.1425; -; .
PDB1VG0; X-ray; 2.20 A; B=1-207
PDB1VG1; X-ray; 1.90 A; A=1-185
PDB1VG8; X-ray; 1.70 A; A/B/C/D=1-207
PDB1VG9; X-ray; 2.50 A; B/D/F/H=1-185
PDBsum1VG0; -; .
PDBsum1VG1; -; .
PDBsum1VG8; -; .
PDBsum1VG9; -; .
ProteinModelPortalP09527; -; .
SMRP09527; 7-190; .
IntActP09527; 2; .
MINTMINT-1775656; -; .
STRINGP09527; -; .
PhosphoSiteP09527; -; .
PRIDEP09527; -; .
EnsemblENSRNOT00000016432; ENSRNOP00000016432; ENSRNOG00000012247; .
GeneID29448; -; .
KEGGrno:29448; -; .
UCSCNM_023950; rat; .
CTD7879; -; .
RGD61908; Rab7a; .
eggNOGmaNOG04930; -; .
GeneTreeENSGT00600000084038; -; .
HOVERGENHBG009351; -; .
InParanoidP09527; -; .
OrthoDBEOG4QFWF4; -; .
PhylomeDBP09527; -; .
NextBio609213; -; .
ArrayExpressP09527; -; .
GenevestigatorP09527; -; .
GermOnlineENSRNOG00000012247; Rattus norvegicus; .
GOGO:0042599; C:lamellar body; IDA:RGD; .
GOGO:0005770; C:late endosome; IDA:RGD; .
GOGO:0005764; C:lysosome; IEA:UniProtKB-SubCell; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell; .
GOGO:0019003; F:GDP binding; IDA:RGD; .
GOGO:0005525; F:GTP binding; IDA:RGD; .
GOGO:0003924; F:GTPase activity; TAS:RGD; .
GOGO:0048365; F:Rac GTPase binding; IPI:RGD; .
GOGO:0045453; P:bone resorption; IMP:RGD; .
GOGO:0015031; P:protein transport; IEA:UniProtKB-KW; .
GOGO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro; .
InterProIPR005225; Small_GTP-bd_dom; .
InterProIPR001806; Small_GTPase; .
InterProIPR003579; Small_GTPase_Rab_type; .
KOK07897; -; .
PfamPF00071; Ras; 1; .
SMARTSM00175; RAB; 1; .
TIGRFAMsTIGR00231; Small_GTP; 1; .
PROSITEPS51419; RAB; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server