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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0021]' for entry matching: P10639 World-2DPAGE Repository (0021):  P10639 P10639 General information about the entry View entry in simple text format Entry name THIO_MOUSE Primary accession number P10639 integrated into World-2DPAGE Repository (0021) on  June 9, 2010 (release 1) 2D Annotations were last modified on June 20, 2011 (version 2) General Annotations were last modified on  November 30, 2011 (version 2) Name and origin of the protein Description RecName: Full=Thioredoxin; Short=Trx; AltName: Full=ATL-derived factor; Short=ADF;. Gene name Name=Txn Synonyms=Txn1 Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D-PAGE GEL CHARACTERIZATION De Cegli R., Romito A., Iacobacci S., Mao L., Lauria M., Fedele A.O., Klose J., Borel C., Descombes P., Antonarakis S.E., Di Bernardo D., Banfi S., Ballabio A., Cobellis G. ''A mouse Embryonic Stem Cell Bank for inducible overexpression of human Chromosome 21 genes'' Genome Biol 11(6):R64 (2010) 2D PAGE maps for identified proteins How to interpret a protein RUNX1_DAY7 {Mouse embryonic stem cells overexpressing Runx1, Day 7} Mus musculus (Mouse) Tissue: Embryonic stem cell   map experimental info   RUNX1_DAY7 MAP LOCATIONS: SPOT 3567: pI=4.80; Mw=11600   [identification data] EXPRESSION: SPOT 3567: Protein ratio 48h/0h=1.64 [1]. IDENTIFICATION: SPOT 3567: Mascot Protein score=75. SeqCov=29%. Peptides identified=3 [1]. MAPPING (identification): SPOT 3567: Tandem mass spectrometry [1]. Copyright Data from Dr. Lei Mao, Institute of Human Genetics, Charite Universitaetsmedizin Berlin, Germany Cross-references UniProtKB/Swiss-Prot P10639; THIO_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name THIO_MOUSE Primary accession number P10639 Secondary accession number(s) Q52KC4 Q9D8R0 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  November 16, 2011 (version 113) Name and origin of the protein Description RecName: Full=Thioredoxin; Short=Trx; AltName: Full=ATL-derived factor; Short=ADF; Gene name Name=Txn Synonyms=Txn1 Encoded on Name=Txn; Synonyms=Txn1 Keywords Acetylation; Activator; Complete proteome; Cytoplasm; Disulfide bond; Electron transport; Nucleus; Redox-active center; Reference proteome; S-nitrosylation; Secreted; Transcription; Transcription regulation; Transport. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X77585; CAA54688.1; -; mRNA EMBL D21859; BAA04881.1; -; Genomic_DNA EMBL AK007537; BAB25096.1; -; mRNA EMBL AK007790; BAB25256.1; -; mRNA EMBL BC010756; AAH10756.1; -; mRNA EMBL BC094415; AAH94415.1; -; mRNA IPI IPI00226993; -; . PIR JC4068; S04107; . RefSeq NP_035790.1; NM_011660.3; . UniGene Mm.260618; -; . ProteinModelPortal P10639; -; . SMR P10639; 1-103; . IntAct P10639; 1; . STRING P10639; -; . PhosphoSite P10639; -; . SWISS-2DPAGE P10639; -; . UCD-2DPAGE P10639; -; . PRIDE P10639; -; . Ensembl ENSMUST00000030051; ENSMUSP00000030051; ENSMUSG00000028367; . GeneID 22166; -; . KEGG mmu:22166; -; . CTD 22166; -; . MGI MGI:98874; Txn1; . GeneTree ENSGT00530000063008; -; . HOGENOM HBG493509; -; . HOVERGEN HBG009243; -; . InParanoid P10639; -; . OMA ITTKESW; -; . OrthoDB EOG47PX7J; -; . PhylomeDB P10639; -; . NextBio 302106; -; . ArrayExpress P10639; -; . Bgee P10639; -; . CleanEx MM_TXN1; -; . Genevestigator P10639; -; . GermOnline ENSMUSG00000028367; Mus musculus; . GO GO:0005829; C:cytosol; IDA:MGI; . GO GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell; . GO GO:0005739; C:mitochondrion; IDA:MGI; . GO GO:0005634; C:nucleus; IDA:MGI; . GO GO:0009055; F:electron carrier activity; IEA:InterPro; . GO GO:0015037; F:peptide disulfide oxidoreductase activity; IDA:MGI; . GO GO:0005515; F:protein binding; IPI:MGI; . GO GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro; . GO GO:0045454; P:cell redox homeostasis; IDA:MGI; . GO GO:0022900; P:electron transport chain; IEA:UniProtKB-KW; . GO GO:0006662; P:glycerol ether metabolic process; IEA:InterPro; . GO GO:0046826; P:negative regulation of protein export from nucleus; IDA:MGI; . GO GO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB; . GO GO:0033158; P:regulation of protein import into nucleus; translocation; ISS:UniProtKB GO GO:0006355; P:regulation of transcription; DNA-dependent; IEA:UniProtKB-KW GO GO:0009314; P:response to radiation; ISS:UniProtKB; . GO GO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW GO GO:0006810; P:transport; IEA:UniProtKB-KW; . InterPro IPR005746; Thioredoxin; . InterPro IPR012336; Thioredoxin-like_fold; . InterPro IPR017937; Thioredoxin_CS; . InterPro IPR013766; Thioredoxin_domain; . Gene3D G3DSA:3.40.30.10; Thioredoxin_fold; 1; . KO K03671; -; . PANTHER PTHR10438; Trx; 1; . Pfam PF00085; Thioredoxin; 1; . PIRSF PIRSF000077; Thioredoxin; 1; . PRINTS PR00421; THIOREDOXIN; . SUPFAM SSF52833; Thiordxn-like_fd; 1; . PROSITE PS00194; THIOREDOXIN_1; 1; . PROSITE PS51352; THIOREDOXIN_2; 1; . World-2DPAGE Repository (search AC)