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Searching in 'World-2DPAGE Repository [0021]' for entry matching: P10639

World-2DPAGE Repository (0021):  P10639


General information about the entry
View entry in simple text format
Entry nameTHIO_MOUSE
Primary accession numberP10639
integrated into World-2DPAGE Repository (0021) on June 9, 2010 (release 1)
2D Annotations were last modified onJune 20, 2011 (version 2)
General Annotations were last modified on November 30, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Thioredoxin; Short=Trx; AltName: Full=ATL-derived factor; Short=ADF;.
Gene nameName=Txn
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
De Cegli R., Romito A., Iacobacci S., Mao L., Lauria M., Fedele A.O., Klose J., Borel C., Descombes P., Antonarakis S.E., Di Bernardo D., Banfi S., Ballabio A., Cobellis G.
''A mouse Embryonic Stem Cell Bank for inducible overexpression of human Chromosome 21 genes''
Genome Biol 11(6):R64 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RUNX1_DAY7 {Mouse embryonic stem cells overexpressing Runx1, Day 7}
Mus musculus (Mouse)
Tissue: Embryonic stem cell
  map experimental info

pI=4.80; Mw=11600  [identification data]

SPOT 3567: Protein ratio 48h/0h=1.64 [1].

IDENTIFICATION: SPOT 3567: Mascot Protein score=75. SeqCov=29%. Peptides identified=3 [1].
MAPPING (identification):
SPOT 3567: Tandem mass spectrometry [1].

Data from Dr. Lei Mao, Institute of Human Genetics, Charite Universitaetsmedizin Berlin, Germany
UniProtKB/Swiss-ProtP10639; THIO_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameTHIO_MOUSE
Primary accession numberP10639
Secondary accession number(s) Q52KC4 Q9D8R0
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 113)
Name and origin of the protein
DescriptionRecName: Full=Thioredoxin; Short=Trx; AltName: Full=ATL-derived factor; Short=ADF;
Gene nameName=Txn
Encoded onName=Txn; Synonyms=Txn1
KeywordsAcetylation; Activator; Complete proteome; Cytoplasm; Disulfide bond; Electron transport; Nucleus; Redox-active center; Reference proteome; S-nitrosylation; Secreted; Transcription; Transcription regulation; Transport.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX77585; CAA54688.1; -; mRNA
EMBLD21859; BAA04881.1; -; Genomic_DNA
EMBLAK007537; BAB25096.1; -; mRNA
EMBLAK007790; BAB25256.1; -; mRNA
EMBLBC010756; AAH10756.1; -; mRNA
EMBLBC094415; AAH94415.1; -; mRNA
IPIIPI00226993; -; .
PIRJC4068; S04107; .
RefSeqNP_035790.1; NM_011660.3; .
UniGeneMm.260618; -; .
ProteinModelPortalP10639; -; .
SMRP10639; 1-103; .
IntActP10639; 1; .
STRINGP10639; -; .
PhosphoSiteP10639; -; .
SWISS-2DPAGEP10639; -; .
UCD-2DPAGEP10639; -; .
PRIDEP10639; -; .
EnsemblENSMUST00000030051; ENSMUSP00000030051; ENSMUSG00000028367; .
GeneID22166; -; .
KEGGmmu:22166; -; .
CTD22166; -; .
MGIMGI:98874; Txn1; .
GeneTreeENSGT00530000063008; -; .
HOGENOMHBG493509; -; .
HOVERGENHBG009243; -; .
InParanoidP10639; -; .
OrthoDBEOG47PX7J; -; .
PhylomeDBP10639; -; .
NextBio302106; -; .
ArrayExpressP10639; -; .
BgeeP10639; -; .
CleanExMM_TXN1; -; .
GenevestigatorP10639; -; .
GermOnlineENSMUSG00000028367; Mus musculus; .
GOGO:0005829; C:cytosol; IDA:MGI; .
GOGO:0005576; C:extracellular region; IEA:UniProtKB-SubCell; .
GOGO:0005739; C:mitochondrion; IDA:MGI; .
GOGO:0005634; C:nucleus; IDA:MGI; .
GOGO:0009055; F:electron carrier activity; IEA:InterPro; .
GOGO:0015037; F:peptide disulfide oxidoreductase activity; IDA:MGI; .
GOGO:0005515; F:protein binding; IPI:MGI; .
GOGO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro; .
GOGO:0045454; P:cell redox homeostasis; IDA:MGI; .
GOGO:0022900; P:electron transport chain; IEA:UniProtKB-KW; .
GOGO:0006662; P:glycerol ether metabolic process; IEA:InterPro; .
GOGO:0046826; P:negative regulation of protein export from nucleus; IDA:MGI; .
GOGO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB; .
GOGO:0033158; P:regulation of protein import into nucleus; translocation; ISS:UniProtKB
GOGO:0006355; P:regulation of transcription; DNA-dependent; IEA:UniProtKB-KW
GOGO:0009314; P:response to radiation; ISS:UniProtKB; .
GOGO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW
GOGO:0006810; P:transport; IEA:UniProtKB-KW; .
InterProIPR005746; Thioredoxin; .
InterProIPR012336; Thioredoxin-like_fold; .
InterProIPR017937; Thioredoxin_CS; .
InterProIPR013766; Thioredoxin_domain; .
Gene3DG3DSA:; Thioredoxin_fold; 1; .
KOK03671; -; .
PANTHERPTHR10438; Trx; 1; .
PfamPF00085; Thioredoxin; 1; .
PIRSFPIRSF000077; Thioredoxin; 1; .
SUPFAMSSF52833; Thiordxn-like_fd; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server