Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: P14314 World-2DPAGE Repository (0054):  P14314 P14314 General information about the entry View entry in simple text format Entry name GLU2B_HUMAN Primary accession number P14314 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Glucosidase 2 subunit beta; AltName: Full=80K-H protein; AltName: Full=Glucosidase II subunit beta; AltName: Full=Protein kinase C substrate 60.1 kDa protein heavy chain; Short=PKCSH; Flags: Precursor;. Gene name Name=PRKCSH Synonyms=G19P1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 433: pI=4.33; Mw=57816   [identification data] %COV: SPOT 433: 38 [1]. SCORE: SPOT 433: 480 [1]. SEARCH ENGINE: SPOT 433: Mascot [1]. MAPPING (identification): SPOT 433: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P14314; GLU2B_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GLU2B_HUMAN Primary accession number P14314 Secondary accession number(s) A8K318 Q96BU9 Q96D06 Q9P0W9 Sequence was last modified on  October 17, 2006 (version 2) Annotations were last modified on  October 1, 2014 (version 161) Name and origin of the protein Description RecName: Full=Glucosidase 2 subunit beta; AltName: Full=80K-H protein; AltName: Full=Glucosidase II subunit beta; AltName: Full=Protein kinase C substrate 60.1 kDa protein heavy chain; Short=PKCSH; Flags: Precursor; Gene name Name=PRKCSH Synonyms=G19P1 Encoded on Name=PRKCSH; Synonyms=G19P1 Keywords Alternative splicing; Calcium; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Glycoprotein; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Signal. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J03075; AAA52493.1; -; mRNA EMBL U50326; AAA98668.1; -; Genomic_DNA EMBL U50317; AAA98668.1; JOINED; Genomic_DNA EMBL U50318; AAA98668.1; JOINED; Genomic_DNA EMBL U50319; AAA98668.1; JOINED; Genomic_DNA EMBL U50320; AAA98668.1; JOINED; Genomic_DNA EMBL U50321; AAA98668.1; JOINED; Genomic_DNA EMBL U50322; AAA98668.1; JOINED; Genomic_DNA EMBL U50323; AAA98668.1; JOINED; Genomic_DNA EMBL U50324; AAA98668.1; JOINED; Genomic_DNA EMBL U50325; AAA98668.1; JOINED; Genomic_DNA EMBL AF144075; AAF66686.1; -; mRNA EMBL BT009858; AAP88860.1; -; mRNA EMBL AK290433; BAF83122.1; -; mRNA EMBL AC008481; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC024575; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC013586; AAH13586.2; -; mRNA EMBL BC015154; AAH15154.1; ALT_INIT; mRNA CCDS CCDS32911.1; -. [P14314-1]; . CCDS CCDS45977.1; -. [P14314-2]; . PIR A32469; A32469; . RefSeq NP_001001329.1; NM_001001329.2. [P14314-2]; . RefSeq NP_001276031.1; NM_001289102.1. [P14314-2]; . RefSeq NP_002734.2; NM_002743.3. [P14314-1]; . UniGene Hs.610830; -; . ProteinModelPortal P14314; -; . SMR P14314; 423-512; . BioGrid 111575; 28; . IntAct P14314; 13; . MINT MINT-1380114; -; . STRING 9606.ENSP00000252455; -; . PhosphoSite P14314; -; . DMDM 116242499; -; . MaxQB P14314; -; . PaxDb P14314; -; . PRIDE P14314; -; . DNASU 5589; -; . Ensembl ENST00000586486; ENSP00000465948; ENSG00000130175; . Ensembl ENST00000587327; ENSP00000466012; ENSG00000130175. [P14314-2]; . Ensembl ENST00000589838; ENSP00000465461; ENSG00000130175. [P14314-1]; . Ensembl ENST00000591462; ENSP00000465489; ENSG00000130175. [P14314-2]; . GeneID 5589; -; . KEGG hsa:5589; -; . UCSC uc002mrt.3; human. [P14314-1]; . UCSC uc002mru.3; human. [P14314-2]; . CTD 5589; -; . GeneCards GC19P011546; -; . HGNC HGNC:9411; PRKCSH; . HPA CAB004465; -; . HPA HPA041940; -; . MIM 174050; phenotype; . MIM 177060; gene; . neXtProt NX_P14314; -; . Orphanet 2924; Isolated polycystic liver disease; . PharmGKB PA33774; -; . eggNOG NOG289998; -; . HOGENOM HOG000007805; -; . HOVERGEN HBG051738; -; . InParanoid P14314; -; . KO K08288; -; . OrthoDB EOG7DZ8JX; -; . PhylomeDB P14314; -; . TreeFam TF329550; -; . BRENDA 3.2.1.84; 2681; . Reactome REACT_23810; Calnexin/calreticulin cycle; . Reactome REACT_23878; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; . Reactome REACT_25195; Advanced glycosylation endproduct receptor signaling; . SignaLink P14314; -; . UniPathway UPA00957; -; . ChiTaRS PRKCSH; human; . GeneWiki PRKCSH; -; . GenomeRNAi 5589; -; . NextBio 21678; -; . PMAP-CutDB P14314; -; . PRO PR:P14314; -; . ArrayExpress P14314; -; . Bgee P14314; -; . CleanEx HS_PRKCSH; -; . Genevestigator P14314; -; . GO GO:0005783; C:endoplasmic reticulum; IDA:UniProt; . GO GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome; . GO GO:0005622; C:intracellular; NAS:UniProtKB; . GO GO:0005509; F:calcium ion binding; IEA:InterPro; . GO GO:0044325; F:ion channel binding; IPI:UniProt; . GO GO:0051219; F:phosphoprotein binding; IPI:UniProt; . GO GO:0005080; F:protein kinase C binding; IPI:UniProtKB; . GO GO:0003723; F:RNA binding; IEA:Ensembl; . GO GO:0044267; P:cellular protein metabolic process; TAS:Reactome; . GO GO:0001701; P:in utero embryonic development; IEA:Ensembl; . GO GO:0045087; P:innate immune response; TAS:Reactome; . GO GO:0035556; P:intracellular signal transduction; NAS:UniProtKB; . GO GO:0001889; P:liver development; IEA:Ensembl; . GO GO:0006491; P:N-glycan processing; IEA:InterPro; . GO GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl; . GO GO:0006807; P:nitrogen compound metabolic process; IEA:Ensembl; . GO GO:0043687; P:post-translational protein modification; TAS:Reactome; . GO GO:0006457; P:protein folding; TAS:Reactome; . GO GO:0051291; P:protein heterooligomerization; IEA:Ensembl; . GO GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome; . GO GO:0072001; P:renal system development; IEA:Ensembl; . Gene3D 2.70.130.10; -; 1; . Gene3D 4.10.400.10; -; 2; . InterPro IPR018247; EF_Hand_1_Ca_BS; . InterPro IPR002048; EF_hand_dom; . InterPro IPR026874; Glucosidase_2_bsu; . InterPro IPR002172; LDrepeatLR_classA_rpt; . InterPro IPR009011; Man6P_isomerase_rcpt-bd_dom; . InterPro IPR028146; PRKCSH_N; . PANTHER PTHR12630:SF1; PTHR12630:SF1; 1; . Pfam PF13202; EF-hand_5; 2; . Pfam PF12999; PRKCSH-like; 1; . SMART SM00192; LDLa; 1; . SUPFAM SSF50911; SSF50911; 1; . SUPFAM SSF57424; SSF57424; 1; . PROSITE PS00018; EF_HAND_1; 1; . PROSITE PS50222; EF_HAND_2; 1; . PROSITE PS00014; ER_TARGET; 1; . World-2DPAGE Repository (search AC)