resource logo

World-2DPAGE Repository

Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository no longer accepts submissions.


World-2DPAGE Repository 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Databases

use 'Ctrl' to select several
databases


Select Remote Interfaces
[All Interfaces]
SWISS-2DPAGE
World-2DPAGE Portal

Exclude local DBs
has only effect if a remote
interface is selected
     
Searching in 'World-2DPAGE Repository [0054]' for entry matching: P14854




World-2DPAGE Repository (0054):  P14854


P14854


General information about the entry
View entry in simple text format
Entry nameCX6B1_HUMAN
Primary accession numberP14854
integrated into World-2DPAGE Repository (0054) on November 28, 2012 (release 1)
2D Annotations were last modified onNovember 28, 2012 (version 1)
General Annotations were last modified on October 23, 2014 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Cytochrome c oxidase subunit 6B1; AltName: Full=Cytochrome c oxidase subunit VIb isoform 1; Short=COX VIb-1;.
Gene nameName=COX6B1
Synonyms=COX6B
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
DOI=10.1074/mcp.M112.022947;
Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P.
''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects''
Molecular & Cellular Proteomics 12(7):1764-1779 (2013)
2D PAGE maps for identified proteins
How to interpret a protein

HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)}
Homo sapiens (Human)
HSAPIENS_CCRF-CEM_3-10
  map experimental info
 
HSAPIENS_CCRF-CEM_3-10

MAP LOCATIONS:
pI=6.79; Mw=10061  [identification data]

%COV: SPOT 1386: 65 [1].
SCORE: SPOT 1386: 116 [1].
SEARCH ENGINE: SPOT 1386: Mascot [1].
MAPPING (identification):
SPOT 1386: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg
Cross-references
UniProtKB/Swiss-ProtP14854; CX6B1_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameCX6B1_HUMAN
Primary accession numberP14854
Secondary accession number(s) B2R5C9 Q6IBL4
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 1, 2014 (version 139)
Name and origin of the protein
DescriptionRecName: Full=Cytochrome c oxidase subunit 6B1; AltName: Full=Cytochrome c oxidase subunit VIb isoform 1; Short=COX VIb-1;
Gene nameName=COX6B1
Synonyms=COX6B
Encoded onName=COX6B1; Synonyms=COX6B
KeywordsAcetylation; Complete proteome; Disease mutation; Disulfide bond; Mitochondrion; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX13923; CAA32114.1; -; mRNA
EMBLX54473; CAA38352.1; -; mRNA
EMBLAK312140; BAG35076.1; -; mRNA
EMBLBT006945; AAP35591.1; -; mRNA
EMBLCR456789; CAG33070.1; -; mRNA
EMBLCR542137; CAG46934.1; -; mRNA
EMBLAC002115; AAB57628.1; -; Genomic_DNA
EMBLBC001015; AAH01015.1; -; mRNA
EMBLBC002478; AAH02478.1; -; mRNA
EMBLX58139; CAA41147.1; -; Genomic_DNA
CCDSCCDS12469.1; -; .
PIRS03287; OGHU6B; .
RefSeqNP_001854.1; NM_001863.4; .
UniGeneHs.431668; -; .
ProteinModelPortalP14854; -; .
SMRP14854; 8-86; .
BioGrid107733; 6; .
IntActP14854; 4; .
MINTMINT-3008230; -; .
STRING9606.ENSP00000246554; -; .
PhosphoSiteP14854; -; .
DMDM117115; -; .
MaxQBP14854; -; .
PaxDbP14854; -; .
PRIDEP14854; -; .
DNASU1340; -; .
EnsemblENST00000246554; ENSP00000246554; ENSG00000126267; .
EnsemblENST00000392201; ENSP00000376037; ENSG00000126267; .
EnsemblENST00000592141; ENSP00000466818; ENSG00000126267; .
GeneID1340; -; .
KEGGhsa:1340; -; .
UCSCuc002oav.3; human; .
CTD1340; -; .
GeneCardsGC19P036140; -; .
HGNCHGNC:2280; COX6B1; .
HPAHPA004192; -; .
MIM124089; gene; .
MIM220110; phenotype; .
neXtProtNX_P14854; -; .
Orphanet254905; Isolated cytochrome C oxidase deficiency; .
Orphanet70474; Leigh syndrome with cardiomyopathy; .
PharmGKBPA26797; -; .
eggNOGNOG279294; -; .
HOGENOMHOG000165128; -; .
HOVERGENHBG051090; -; .
InParanoidP14854; -; .
KOK02267; -; .
OMAISRIREW; -; .
OrthoDBEOG7WDN54; -; .
PhylomeDBP14854; -; .
TreeFamTF105065; -; .
ReactomeREACT_22393; Respiratory electron transport; .
ChiTaRSCOX6B1; human; .
GeneWikiCOX6B1; -; .
GenomeRNAi1340; -; .
NextBio5443; -; .
PROPR:P14854; -; .
ArrayExpressP14854; -; .
BgeeP14854; -; .
CleanExHS_COX6B1; -; .
GenevestigatorP14854; -; .
GOGO:0005743; C:mitochondrial inner membrane; TAS:Reactome; .
GOGO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell; .
GOGO:0005739; C:mitochondrion; IDA:HPA; .
GOGO:0004129; F:cytochrome-c oxidase activity; NAS:UniProtKB; .
GOGO:0044237; P:cellular metabolic process; TAS:Reactome; .
GOGO:1902600; P:hydrogen ion transmembrane transport; NAS:GOC; .
GOGO:0022904; P:respiratory electron transport chain; TAS:Reactome; .
GOGO:0044281; P:small molecule metabolic process; TAS:Reactome; .
GOGO:0021762; P:substantia nigra development; IEP:UniProt; .
Gene3D1.10.10.140; -; 1; .
InterProIPR003213; Cyt_c_oxidase_su6B; .
PfamPF02297; COX6B; 1; .
PIRSFPIRSF000278; Cyt_c_oxidase_6B; 1; .
SUPFAMSSF47694; SSF47694; 1; .



World-2DPAGE Repository image

World-2DPAGE Repository (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server