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Searching in 'World-2DPAGE Repository [0043]' for entry matching: P17918

World-2DPAGE Repository (0043):  P17918


General information about the entry
View entry in simple text format
Entry namePCNA_MOUSE
Primary accession numberP17918
integrated into World-2DPAGE Repository (0043) on January 4, 2012 (release 1)
2D Annotations were last modified onJanuary 6, 2012 (version 1)
General Annotations were last modified on April 18, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Proliferating cell nuclear antigen; Short=PCNA; AltName: Full=Cyclin;.
Gene nameName=Pcna
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
DOI=10.1016/j.jprot.2012.04.001 ;
Sun Z., Biela L.M., Hamilton K.L., Reardon K.F.
''Concentration-dependent effects of the soy phytoestrogen genistein on the proteome of cultured cardiomyocytes''
Journal of Proteomics 0(0):0-0 (2012)
2D PAGE maps for identified proteins
How to interpret a protein

MMUSCULUS_HL-1PHO_4-7 {mouse HL-1 cultured cardiomyocytes hydrophobic extraction}
Mus musculus (Mouse)
Tissue: Cardiac myocyte
  map experimental info

Mw=29108  [identification data]

%COV: BAND pho15: 8 [1].
SCORE: BAND pho15: 166 [1].
SEARCH ENGINE: BAND pho15: Mascot [1].
MAPPING (identification):
BAND pho15: Tandem mass spectrometry [1].

Data from Dr. Zeyu Sun, Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, USA
UniProtKB/Swiss-ProtP17918; PCNA_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2012_03
Entry namePCNA_MOUSE
Primary accession numberP17918
Sequence was last modified on March 1, 1992 (version 2)
Annotations were last modified on February 22, 2012 (version 124)
Name and origin of the protein
DescriptionRecName: Full=Proliferating cell nuclear antigen; Short=PCNA; AltName: Full=Cyclin;
Gene nameName=Pcna
Encoded onName=Pcna
KeywordsAcetylation; Complete proteome; DNA replication; DNA-binding; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX53068; CAA37243.1; -; mRNA
EMBLX57800; CAA40938.1; -; Genomic_DNA
EMBLBC005778; AAH05778.1; -; mRNA
EMBLBC010343; AAH10343.1; -; mRNA
IPIIPI00113870; -; .
PIRS15703; WMMS; .
RefSeqNP_035175.1; NM_011045.2; .
UniGeneMm.7141; -; .
ProteinModelPortalP17918; -; .
SMRP17918; 1-257; .
DIPDIP-39409N; -; .
IntActP17918; 6; .
MINTMINT-1510748; -; .
STRINGP17918; -; .
PhosphoSiteP17918; -; .
PRIDEP17918; -; .
EnsemblENSMUST00000028817; ENSMUSP00000028817; ENSMUSG00000027342; .
GeneID18538; -; .
KEGGmmu:18538; -; .
CTD5111; -; .
MGIMGI:97503; Pcna; .
eggNOGCOG0592; -; .
GeneTreeENSGT00390000004965; -; .
HOVERGENHBG000947; -; .
InParanoidP17918; -; .
KOK04802; -; .
OrthoDBEOG4933JJ; -; .
PhylomeDBP17918; -; .
NextBio294312; -; .
ArrayExpressP17918; -; .
BgeeP17918; -; .
CleanExMM_PCNA; -; .
GenevestigatorP17918; -; .
GermOnlineENSMUSG00000027342; Mus musculus; .
GOGO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:MGI; .
GOGO:0005652; C:nuclear lamina; IDA:MGI; .
GOGO:0043626; C:PCNA complex; IEA:InterPro; .
GOGO:0070557; C:PCNA-p21 complex; ISS:UniProtKB; .
GOGO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro; .
GOGO:0006287; P:base-excision repair; gap-filling; IDA:MGI
GOGO:0006260; P:DNA replication; IEA:UniProtKB-KW; .
GOGO:0006886; P:intracellular protein transport; IMP:MGI; .
GOGO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI; .
GOGO:0032077; P:positive regulation of deoxyribonuclease activity; ISS:UniProtKB; .
GOGO:0006275; P:regulation of DNA replication; IEA:InterPro; .
GOGO:0019985; P:translesion synthesis; ISS:UniProtKB; .
InterProIPR000730; Pr_cel_nuc_antig; .
InterProIPR022649; Pr_cel_nuc_antig_C; .
InterProIPR022659; Pr_cel_nuc_antig_CS; .
InterProIPR022648; Pr_cel_nuc_antig_N; .
PANTHERPTHR11352; Pr_cel_nuc_antig; 1; .
PfamPF02747; PCNA_C; 1; .
PfamPF00705; PCNA_N; 1; .
TIGRFAMsTIGR00590; Pcna; 1; .
PROSITEPS01251; PCNA_1; 1; .
PROSITEPS00293; PCNA_2; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server