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Searching in 'World-2DPAGE Repository [0019]' for entry matching: P31044




World-2DPAGE Repository (0019):  P31044

P31044


General information about the entry
View entry in simple text format
Entry namePEBP1_RAT
Primary accession numberP31044
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Phosphatidylethanolamine-binding protein 1; Short=PEBP-1; AltName: Full=23 kDa morphine-binding protein; AltName: Full=HCNPpp; AltName: Full=P23K; Contains: RecName: Full=Hippocampal cholinergic neurostimulating peptide; Short=HCNP;.
Gene nameName=Pebp1
Synonyms=Pbp, Pebp
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info 		 
HIPP_SYNAP

MAP LOCATIONS:
pI=5.48; Mw=20902  [identification data]
pI=5.48; Mw=20902  [identification data]

IDENTIFICATION: SPOT 786: Peptides number=8. SeqCov=46%. MOWSE score=2.46E+5 [1]
SPOT 823: Peptides number=5. SeqCov=47.6%. MOWSE score=4.71E+8 [1].
MAPPING (identification):
SPOT 786: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 823: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP31044; PEBP1_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry namePEBP1_RAT
Primary accession numberP31044
Secondary accession number(s) P31045
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 105)
Name and origin of the protein
DescriptionRecName: Full=Phosphatidylethanolamine-binding protein 1; Short=PEBP-1; AltName: Full=23 kDa morphine-binding protein; AltName: Full=HCNPpp; AltName: Full=P23K; Contains: RecName: Full=Hippocampal cholinergic neurostimulating peptide; Short=HCNP;
Gene nameName=Pebp1
Synonyms=Pbp, Pebp
Encoded onName=Pebp1; Synonyms=Pbp, Pebp
Keywords3D-structure; Acetylation; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Lipid-binding; Membrane; Nucleotide-binding; Phosphoprotein; Protease inhibitor; Reference proteome; Serine protease inhibitor.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX75253; CAA53032.1; -; mRNA
EMBLX75254; CAA53033.1; -; Genomic_DNA
EMBLX71873; CAA50708.1; -; mRNA
EMBLBC063171; AAH63171.1; -; mRNA
IPIIPI00230937; -; .
PIRA36126; A36126; .
PIRS18358; S18358; .
RefSeqNP_058932.1; NM_017236.1; .
UniGeneRn.29745; -; .
PDB2IQX; X-ray; 2.20 A; A/B/C=1-187
PDB2IQY; X-ray; 1.40 A; A=1-187
PDBsum2IQX; -; .
PDBsum2IQY; -; .
ProteinModelPortalP31044; -; .
SMRP31044; 1-187; .
STRINGP31044; -; .
MEROPSI51.002; -; .
PhosphoSiteP31044; -; .
Rat-heart-2DPAGEP31044; -; .
World-2DPAGE0004:P31044; -; .
PRIDEP31044; -; .
EnsemblENSRNOT00000001500; ENSRNOP00000001500; ENSRNOG00000001136; .
GeneID29542; -; .
KEGGrno:29542; -; .
UCSCNM_017236; rat; .
CTD5037; -; .
RGD62017; Pebp1; .
eggNOGroNOG05879; -; .
GeneTreeENSGT00530000063241; -; .
HOVERGENHBG008165; -; .
InParanoidP31044; -; .
OrthoDBEOG4FFD2T; -; .
PhylomeDBP31044; -; .
NextBio609545; -; .
ArrayExpressP31044; -; .
GenevestigatorP31044; -; .
GermOnlineENSRNOG00000001136; Rattus norvegicus; .
GOGO:0045177; C:apical part of cell; IDA:RGD; .
GOGO:0043679; C:axon terminus; IDA:RGD; .
GOGO:0009986; C:cell surface; IDA:RGD; .
GOGO:0005615; C:extracellular space; IDA:RGD; .
GOGO:0005794; C:Golgi apparatus; IDA:RGD; .
GOGO:0005741; C:mitochondrial outer membrane; IDA:RGD; .
GOGO:0043025; C:neuronal cell body; IDA:RGD; .
GOGO:0005791; C:rough endoplasmic reticulum; IDA:RGD; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0008021; C:synaptic vesicle; IDA:RGD; .
GOGO:0019717; C:synaptosome; IDA:RGD; .
GOGO:0005524; F:ATP binding; IDA:RGD; .
GOGO:0008289; F:lipid binding; TAS:RGD; .
GOGO:0051019; F:mitogen-activated protein kinase binding; IDA:RGD; .
GOGO:0005102; F:receptor binding; IDA:RGD; .
GOGO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW; .
GOGO:0007568; P:aging; IEP:RGD; .
GOGO:0007420; P:brain development; IEP:RGD; .
GOGO:0042755; P:eating behavior; IEP:RGD; .
GOGO:0000165; P:MAPKKK cascade; IDA:RGD; .
GOGO:0043409; P:negative regulation of MAPKKK cascade; IMP:RGD; .
GOGO:0001933; P:negative regulation of protein phosphorylation; IMP:RGD; .
GOGO:0060409; P:positive regulation of acetylcholine metabolic process; IDA:RGD; .
GOGO:0043950; P:positive regulation of cAMP-mediated signaling; IMP:RGD; .
GOGO:0045840; P:positive regulation of mitosis; IMP:RGD; .
GOGO:0001505; P:regulation of neurotransmitter levels; IDA:RGD; .
GOGO:0002026; P:regulation of the force of heart contraction; IDA:RGD; .
GOGO:0014823; P:response to activity; IEP:RGD; .
GOGO:0051592; P:response to calcium ion; IEP:RGD; .
GOGO:0051591; P:response to cAMP; IEP:RGD; .
GOGO:0051412; P:response to corticosterone stimulus; IEP:RGD; .
GOGO:0042493; P:response to drug; IEP:RGD; .
GOGO:0051602; P:response to electrical stimulus; IEP:RGD; .
GOGO:0045471; P:response to ethanol; IEP:RGD; .
GOGO:0009408; P:response to heat; IEP:RGD; .
GOGO:0014070; P:response to organic cyclic compound; IEP:RGD; .
GOGO:0010243; P:response to organic nitrogen; IEP:RGD; .
GOGO:0006979; P:response to oxidative stress; IEP:RGD; .
GOGO:0009636; P:response to toxin; IEP:RGD; .
GOGO:0009611; P:response to wounding; IEP:RGD; .
InterProIPR001858; Phosphotidylethanolamine-bd_CS; .
InterProIPR008914; PtdEtn-bd_prot_PEBP; .
Gene3DG3DSA:3.90.280.10; PEBP; 1; .
PfamPF01161; PBP; 1; .
SUPFAMSSF49777; PEBP; 1; .
PROSITEPS01220; PBP; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server