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Searching in 'World-2DPAGE Repository [0054]' for entry matching: P61289 World-2DPAGE Repository (0054):  P61289 P61289 General information about the entry View entry in simple text format Entry name PSME3_HUMAN Primary accession number P61289 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Proteasome activator complex subunit 3; AltName: Full=11S regulator complex subunit gamma; Short=REG-gamma; AltName: Full=Activator of multicatalytic protease subunit 3; AltName: Full=Ki nuclear autoantigen; AltName: Full=Proteasome activator 28 subunit gamma; Short=PA28g; Short=PA28gamma;. Gene name Name=PSME3 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 1004: pI=4.73; Mw=27745   [identification data] %COV: SPOT 1004: 56 [1]. SCORE: SPOT 1004: 389 [1]. SEARCH ENGINE: SPOT 1004: Mascot [1]. MAPPING (identification): SPOT 1004: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P61289; PSME3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PSME3_HUMAN Primary accession number P61289 Secondary accession number(s) A8K9A3 O35563 P97373 Q12920 Q13172 Q9BQD9 Sequence was last modified on  May 10, 2004 (version 1) Annotations were last modified on  October 1, 2014 (version 115) Name and origin of the protein Description RecName: Full=Proteasome activator complex subunit 3; AltName: Full=11S regulator complex subunit gamma; Short=REG-gamma; AltName: Full=Activator of multicatalytic protease subunit 3; AltName: Full=Ki nuclear autoantigen; AltName: Full=Proteasome activator 28 subunit gamma; Short=PA28g; Short=PA28gamma; Gene name Name=PSME3 Encoded on Name=PSME3 Keywords Acetylation; Alternative splicing; Apoptosis; Cell cycle; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Proteasome; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U11292; AAB60335.1; -; mRNA EMBL BT019386; AAV38193.1; -; mRNA EMBL AK292618; BAF85307.1; -; mRNA EMBL AK074999; BAG52046.1; -; mRNA EMBL AC016889; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471152; EAW60893.1; -; Genomic_DNA EMBL BC001423; AAH01423.1; -; mRNA EMBL BC002684; AAH02684.1; -; mRNA EMBL BC008020; AAH08020.1; -; mRNA EMBL U25756; AAA93227.1; -; Genomic_DNA CCDS CCDS11442.1; -. [P61289-2]; . CCDS CCDS45689.1; -; . CCDS CCDS59290.1; -. [P61289-3]; . PIR I38702; A60537; . RefSeq NP_005780.2; NM_005789.3. [P61289-1]; . RefSeq NP_789839.1; NM_176863.2. [P61289-2]; . UniGene Hs.152978; -; . ProteinModelPortal P61289; -; . SMR P61289; 5-64; 112-246; . BioGrid 115492; 73; . IntAct P61289; 39; . MINT MINT-5002653; -; . STRING 9606.ENSP00000293362; -; . PhosphoSite P61289; -; . DMDM 47117724; -; . MaxQB P61289; -; . PaxDb P61289; -; . PRIDE P61289; -; . DNASU 10197; -; . Ensembl ENST00000293362; ENSP00000293362; ENSG00000131467. [P61289-2]; . Ensembl ENST00000441946; ENSP00000409487; ENSG00000131467. [P61289-3]; . Ensembl ENST00000590720; ENSP00000466794; ENSG00000131467. [P61289-1]; . GeneID 10197; -; . KEGG hsa:10197; -; . UCSC uc002ibp.3; human; . UCSC uc002ibq.4; human. [P61289-2]; . CTD 10197; -; . GeneCards GC17P040985; -; . HGNC HGNC:9570; PSME3; . HPA CAB008388; -; . HPA HPA012510; -; . MIM 605129; gene; . neXtProt NX_P61289; -; . PharmGKB PA33916; -; . eggNOG NOG236353; -; . HOVERGEN HBG053745; -; . InParanoid P61289; -; . KO K06698; -; . OMA FVMPGGM; -; . PhylomeDB P61289; -; . TreeFam TF106236; -; . Reactome REACT_111056; Cross-presentation of soluble exogenous antigens (endosomes); . Reactome REACT_111178; ER-Phagosome pathway; . Reactome REACT_1156; Orc1 removal from chromatin; . Reactome REACT_118656; Activation of NF-kappaB in B cells; . Reactome REACT_1221; CDK-mediated phosphorylation and removal of Cdc6; . Reactome REACT_13464; Regulation of activated PAK-2p34 by proteasome mediated degradation; . Reactome REACT_13565; Regulation of ornithine decarboxylase (ODC); . Reactome REACT_150471; Separation of Sister Chromatids; . Reactome REACT_1614; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; . Reactome REACT_172638; Asymmetric localization of PCP proteins; . Reactome REACT_1949; CDT1 association with the CDC6:ORC:origin complex; . Reactome REACT_200766; degradation of AXIN; . Reactome REACT_200841; degradation of DVL; . Reactome REACT_20549; Autodegradation of the E3 ubiquitin ligase COP1; . Reactome REACT_25325; AUF1 (hnRNP D0) destabilizes mRNA; . Reactome REACT_4; Ubiquitin-dependent degradation of Cyclin D1; . Reactome REACT_6761; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; . Reactome REACT_6785; Autodegradation of Cdh1 by Cdh1:APC/C; . Reactome REACT_6821; SCF-beta-TrCP mediated degradation of Emi1; . Reactome REACT_6871; APC/C:Cdc20 mediated degradation of Securin; . Reactome REACT_75842; Antigen processing: Ubiquitination & Proteasome degradation; . Reactome REACT_9003; SCF(Skp2)-mediated degradation of p27/p21; . Reactome REACT_9031; Vpu mediated degradation of CD4; . Reactome REACT_9453; Vif-mediated degradation of APOBEC3G; . ChiTaRS PSME3; human; . GeneWiki PSME3; -; . GenomeRNAi 10197; -; . NextBio 38592; -; . PMAP-CutDB P61289; -; . PRO PR:P61289; -; . ArrayExpress P61289; -; . Bgee P61289; -; . CleanEx HS_PSME3; -; . Genevestigator P61289; -; . GO GO:0005737; C:cytoplasm; IDA:HPA; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProt; . GO GO:0008537; C:proteasome activator complex; IEA:InterPro; . GO GO:0000502; C:proteasome complex; TAS:ProtInc; . GO GO:0061133; F:endopeptidase activator activity; IDA:UniProtKB; . GO GO:0097371; F:MDM2/MDM4 family protein binding; IDA:UniProtKB; . GO GO:0002039; F:p53 binding; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:IntAct; . GO GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome; . GO GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAP-dependent; TAS:Reactome GO GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome; . GO GO:0006915; P:apoptotic process; TAS:Reactome; . GO GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome; . GO GO:0006977; P:DNA damage response; signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome GO GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome; . GO GO:0010467; P:gene expression; TAS:Reactome; . GO GO:0000278; P:mitotic cell cycle; TAS:Reactome; . GO GO:0016071; P:mRNA metabolic process; TAS:Reactome; . GO GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome; . GO GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB; . GO GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; . GO GO:0010950; P:positive regulation of endopeptidase activity; IDA:GOC; . GO GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; . GO GO:0000209; P:protein polyubiquitination; TAS:Reactome; . GO GO:0042981; P:regulation of apoptotic process; TAS:Reactome; . GO GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome; . GO GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB; . GO GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; . GO GO:0016070; P:RNA metabolic process; TAS:Reactome; . GO GO:0044281; P:small molecule metabolic process; TAS:Reactome; . GO GO:0016032; P:viral process; TAS:Reactome; . Gene3D 1.20.120.180; -; 1; . Gene3D 1.20.5.120; -; 1; . InterPro IPR009077; Proteasome_activ_pa28; . InterPro IPR003186; Proteasome_activ_pa28_C; . InterPro IPR003185; Proteasome_activ_pa28_N; . PANTHER PTHR10660; PTHR10660; 1; . Pfam PF02251; PA28_alpha; 1; . Pfam PF02252; PA28_beta; 1; . SUPFAM SSF47216; SSF47216; 2; . World-2DPAGE Repository (search AC)