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Searching in 'World-2DPAGE Repository [0019]' for entry matching: P63261




World-2DPAGE Repository (0019):  P63261


P63261


General information about the entry
View entry in simple text format
Entry nameACTG_HUMAN
Primary accession numberP63261
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Actin, cytoplasmic 2; AltName: Full=Gamma-actin; Contains: RecName: Full=Actin, cytoplasmic 2, N-terminally processed;.
Gene nameName=ACTG1
Synonyms=ACTB, ACTG
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info
 
HIPP_SYNAP

MAP LOCATIONS:
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]
pI=5.31; Mw=42107  [identification data]

IDENTIFICATION: SPOT 548: Peptides number=8. SeqCov=33.3%. MOWSE score=4.88E+13 [1]
SPOT 552: Peptides number=5. SeqCov=21.1%. MOWSE score=1.77E+7 [1]; SPOT 568: Peptides number=6. SeqCov=23.5%. MOWSE score=1.47E+7 [1]; SPOT 570: Peptides number=8. SeqCov=32.8%. MOWSE score=1.46E+6 [1]; SPOT 711: Peptides number=7. SeqCov=33.9%. MOWSE score=4.10E+11 [1]; SPOT 718: Peptides number=5. SeqCov=24%. MOWSE score=4.75E+6 [1]; SPOT 779: Peptides number=5. SeqCov=24%. MOWSE score=4.75E+6 [1]; SPOT 801: Peptides number=8. SeqCov=27.7%. MOWSE score=8.47E+6 [1]; SPOT 804: Peptides number=3. SeqCov=13.6%. MOWSE score=8.80E+4 [1]; SPOT 818: Peptides number=3. SeqCov=15.7%. MOWSE score=4.10E+3 [1]; SPOT 821: Peptides number=3. SeqCov=13.6%. MOWSE score=5.78E+4 [1]; SPOT 845: Peptides number=3. SeqCov=12.5%. MOWSE score=3.79E+3 [1]; SPOT 846: Peptides number=4. SeqCov=18.4%. MOWSE score=1.18E+4 [1]; SPOT 1003: Peptides number=6. SeqCov=22.9%. MOWSE score=6.61E+5 [1]; SPOT 1066: Peptides number=7. SeqCov=38.4%. MOWSE score=1.06E+10 [1]; SPOT 1076: Peptides number=6. SeqCov=32%. MOWSE score=1.06E+10 [1]; SPOT 1078: Peptides number=4. SeqCov=17.1%. MOWSE score=1.23E+4 [1]; SPOT 1116: Peptides number=7. SeqCov=40%. MOWSE score=6.41E+9 [1].
MAPPING (identification):
SPOT 548: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 552: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 568: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 570: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 711: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 718: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 779: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 801: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 804: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 818: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 821: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 845: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 846: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1003: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1066: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1076: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1078: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1116: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP63261; ACTG_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameACTG_HUMAN
Primary accession numberP63261
Secondary accession number(s) A8K7C2 P02571 P14104 P99022 Q5U032 Q96E67
Sequence was last modified on July 21, 1986 (version 1)
Annotations were last modified on December 14, 2011 (version 96)
Name and origin of the protein
DescriptionRecName: Full=Actin, cytoplasmic 2; AltName: Full=Gamma-actin; Contains: RecName: Full=Actin, cytoplasmic 2, N-terminally processed;
Gene nameName=ACTG1
Synonyms=ACTB, ACTG
Encoded onName=ACTG1; Synonyms=ACTB, ACTG
KeywordsAcetylation; ATP-binding; Complete proteome; Cytoplasm; Cytoskeleton; Deafness; Direct protein sequencing; Disease mutation; Methylation; Non-syndromic deafness; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX04098; CAA27723.1; -; mRNA
EMBLM19283; AAA51579.1; -; Genomic_DNA
EMBLAK291937; BAF84626.1; -; mRNA
EMBLBT019856; AAV38659.1; -; mRNA
EMBLBC000292; AAH00292.1; -; mRNA
EMBLBC001920; AAH01920.1; -; mRNA
EMBLBC007442; AAH07442.1; -; mRNA
EMBLBC009848; AAH09848.1; -; mRNA
EMBLBC010999; AAH10999.1; -; mRNA
EMBLBC012050; AAH12050.1; -; mRNA
EMBLBC015005; AAH15005.1; -; mRNA
EMBLBC015695; AAH15695.1; -; mRNA
EMBLBC015779; AAH15779.1; -; mRNA
EMBLBC018774; AAH18774.1; -; mRNA
EMBLBC053572; AAH53572.1; -; mRNA
EMBLM16247; AAA51580.1; -; mRNA
IPIIPI00021440; -; .
PIRA28098; ATHUG; .
PIRJC5818; JC5818; .
RefSeqNP_001186883.1; NM_001199954.1; .
RefSeqNP_001605.1; NM_001614.3; .
UniGeneHs.514581; -; .
ProteinModelPortalP63261; -; .
SMRP63261; 2-375; .
IntActP63261; 34; .
MINTMINT-4998686; -; .
STRINGP63261; -; .
PhosphoSiteP63261; -; .
DMDM54036678; -; .
SWISS-2DPAGEP63261; -; .
DOSAC-COBS-2DPAGEP60709_OR_P63261; -; .
DOSAC-COBS-2DPAGEP63261; -; .
OGPP63261; -; .
PMMA-2DPAGEP63261; -; .
REPRODUCTION-2DPAGEP63261; -; .
PRIDEP63261; -; .
EnsemblENST00000331925; ENSP00000331514; ENSG00000184009; .
GeneID71; -; .
KEGGhsa:71; -; .
UCSCuc002kaj.1; human; .
CTD71; -; .
GeneCardsGC17M074925; -; .
H-InvDBHIX0020804; -; .
HGNCHGNC:144; ACTG1; .
HPACAB013531; -; .
MIM102560; gene; .
MIM604717; phenotype; .
neXtProtNX_P63261; -; .
Orphanet90635; Autosomal dominant nonsyndromic sensorineural deafness type DFNA; .
PharmGKBPA24468; -; .
HOVERGENHBG003771; -; .
InParanoidP63261; -; .
OMAIAMEEEI; -; .
OrthoDBEOG41JZC9; -; .
PhylomeDBP63261; -; .
ReactomeREACT_111045; Developmental Biology; .
ReactomeREACT_111155; Cell-Cell communication; .
ReactomeREACT_11123; Membrane Trafficking; .
ReactomeREACT_604; Hemostasis; .
NextBio279; -; .
PMAP-CutDBP63261; -; .
ArrayExpressP63261; -; .
BgeeP63261; -; .
CleanExHS_ACTB; -; .
CleanExHS_ACTG1; -; .
GenevestigatorP63261; -; .
GermOnlineENSG00000184009; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0042802; F:identical protein binding; IPI:IntAct; .
GOGO:0005200; F:structural constituent of cytoskeleton; IC:UniProtKB; .
GOGO:0034332; P:adherens junction organization; TAS:Reactome; .
GOGO:0007411; P:axon guidance; TAS:Reactome; .
GOGO:0007596; P:blood coagulation; TAS:Reactome; .
GOGO:0034329; P:cell junction assembly; TAS:Reactome; .
GOGO:0006928; P:cellular component movement; TAS:UniProtKB; .
InterProIPR004000; Actin-like; .
InterProIPR020902; Actin/actin-like_CS; .
InterProIPR004001; Actin_CS; .
KOK05692; -; .
PANTHERPTHR11937; Actin_like; 1; .
PfamPF00022; Actin; 1; .
PRINTSPR00190; ACTIN; .
SMARTSM00268; ACTIN; 1; .
PROSITEPS00406; ACTINS_1; 1; .
PROSITEPS00432; ACTINS_2; 1; .
PROSITEPS01132; ACTINS_ACT_LIKE; 1; .



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World-2DPAGE Repository (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server