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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: P63261 World-2DPAGE Repository (0054):  P63261 P63261 General information about the entry View entry in simple text format Entry name ACTG_HUMAN Primary accession number P63261 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Actin, cytoplasmic 2; AltName: Full=Gamma-actin; Contains: RecName: Full=Actin, cytoplasmic 2, N-terminally processed;. Gene name Name=ACTG1 Synonyms=ACTB, ACTG Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 293: pI=5.31; Mw=41793   [identification data] %COV: SPOT 293: 51 [1]. SCORE: SPOT 293: 415 [1]. SEARCH ENGINE: SPOT 293: Mascot [1]. MAPPING (identification): SPOT 293: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P63261; ACTG_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ACTG_HUMAN Primary accession number P63261 Secondary accession number(s) A8K7C2 P02571 P14104 P99022 Q5U032 Q96E67 Sequence was last modified on  July 21, 1986 (version 1) Annotations were last modified on  October 1, 2014 (version 127) Name and origin of the protein Description RecName: Full=Actin, cytoplasmic 2; AltName: Full=Gamma-actin; Contains: RecName: Full=Actin, cytoplasmic 2, N-terminally processed; Gene name Name=ACTG1 Synonyms=ACTB, ACTG Encoded on Name=ACTG1; Synonyms=ACTB, ACTG Keywords Acetylation; ATP-binding; Complete proteome; Cytoplasm; Cytoskeleton; Deafness; Direct protein sequencing; Disease mutation; Mental retardation; Methylation; Non-syndromic deafness; Nucleotide-binding; Oxidation; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X04098; CAA27723.1; -; mRNA EMBL M19283; AAA51579.1; -; Genomic_DNA EMBL AK291937; BAF84626.1; -; mRNA EMBL BT019856; AAV38659.1; -; mRNA EMBL BC000292; AAH00292.1; -; mRNA EMBL BC001920; AAH01920.1; -; mRNA EMBL BC007442; AAH07442.1; -; mRNA EMBL BC009848; AAH09848.1; -; mRNA EMBL BC010999; AAH10999.1; -; mRNA EMBL BC012050; AAH12050.1; -; mRNA EMBL BC015005; AAH15005.1; -; mRNA EMBL BC015695; AAH15695.1; -; mRNA EMBL BC015779; AAH15779.1; -; mRNA EMBL BC018774; AAH18774.1; -; mRNA EMBL BC053572; AAH53572.1; -; mRNA EMBL M16247; AAA51580.1; -; mRNA CCDS CCDS11782.1; -; . PIR A28098; ATHUG; . PIR JC5818; JC5818; . RefSeq NP_001186883.1; NM_001199954.1; . RefSeq NP_001605.1; NM_001614.3; . UniGene Hs.514581; -; . UniGene Hs.713764; -; . ProteinModelPortal P63261; -; . SMR P63261; 6-375; . BioGrid 106586; 91; . IntAct P63261; 40; . MINT MINT-4998686; -; . STRING 9606.ENSP00000331514; -; . PhosphoSite P63261; -; . DMDM 54036678; -; . DOSAC-COBS-2DPAGE P60709_OR_P63261; -; . DOSAC-COBS-2DPAGE P63261; -; . OGP P63261; -; . REPRODUCTION-2DPAGE P63261; -; . SWISS-2DPAGE P63261; -; . MaxQB P63261; -; . PRIDE P63261; -; . DNASU 71; -; . Ensembl ENST00000331925; ENSP00000331514; ENSG00000184009; . Ensembl ENST00000573283; ENSP00000458435; ENSG00000184009; . Ensembl ENST00000575087; ENSP00000459124; ENSG00000184009; . Ensembl ENST00000575842; ENSP00000458162; ENSG00000184009; . Ensembl ENST00000576544; ENSP00000461672; ENSG00000184009; . GeneID 71; -; . KEGG hsa:71; -; . UCSC uc002kak.2; human; . CTD 71; -; . GeneCards GC17M079476; -; . GeneReviews ACTG1; -; . H-InvDB HIX0001479; -; . H-InvDB HIX0199868; -; . HGNC HGNC:144; ACTG1; . HPA CAB013531; -; . HPA HPA041264; -; . HPA HPA041271; -; . MIM 102560; gene; . MIM 604717; phenotype; . MIM 614583; phenotype; . neXtProt NX_P63261; -; . Orphanet 90635; Autosomal dominant nonsyndromic sensorineural deafness type DFNA; . Orphanet 2995; Baraitser-Winter syndrome; . PharmGKB PA24468; -; . HOVERGEN HBG003771; -; . InParanoid P63261; -; . KO K05692; -; . OMA DARAPIM; -; . PhylomeDB P63261; -; . TreeFam TF354237; -; . Reactome REACT_11035; Gap junction degradation; . Reactome REACT_11049; Formation of annular gap junctions; . Reactome REACT_147867; Translocation of GLUT4 to the plasma membrane; . Reactome REACT_160086; Regulation of actin dynamics for phagocytic cup formation; . Reactome REACT_19195; Adherens junctions interactions; . Reactome REACT_20649; Cell-extracellular matrix interactions; . Reactome REACT_22266; Interaction between L1 and Ankyrins; . Reactome REACT_22365; Recycling pathway of L1; . SignaLink P63261; -; . ChiTaRS ACTG1; human; . GeneWiki ACTG1; -; . GenomeRNAi 71; -; . NextBio 279; -; . PMAP-CutDB P63261; -; . PRO PR:P63261; -; . Bgee P63261; -; . CleanEx HS_ACTB; -; . CleanEx HS_ACTG1; -; . Genevestigator P63261; -; . GO GO:0072562; C:blood microparticle; IDA:UniProt; . GO GO:0005856; C:cytoskeleton; TAS:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005615; C:extracellular space; IDA:UniProt; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProtKB; . GO GO:0031941; C:filamentous actin; IEA:Ensembl; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0030016; C:myofibril; IEA:Ensembl; . GO GO:0005634; C:nucleus; IDA:UniProt; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0005515; F:protein binding; IPI:IntAct; . GO GO:0005200; F:structural constituent of cytoskeleton; IC:UniProtKB; . GO GO:0034332; P:adherens junction organization; TAS:Reactome; . GO GO:0007411; P:axon guidance; TAS:Reactome; . GO GO:0034329; P:cell junction assembly; TAS:Reactome; . GO GO:0045216; P:cell-cell junction organization; TAS:Reactome; . GO GO:0006928; P:cellular component movement; TAS:UniProtKB; . GO GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome; . GO GO:0045087; P:innate immune response; TAS:Reactome; . GO GO:0061024; P:membrane organization; TAS:Reactome; . GO GO:0001895; P:retina homeostasis; IEP:UniProt; . GO GO:0045214; P:sarcomere organization; IEA:Ensembl; . InterPro IPR004000; Actin-related; . InterPro IPR020902; Actin/actin-like_CS; . InterPro IPR004001; Actin_CS; . PANTHER PTHR11937; PTHR11937; 1; . Pfam PF00022; Actin; 1; . PRINTS PR00190; ACTIN; . SMART SM00268; ACTIN; 1; . PROSITE PS00406; ACTINS_1; 1; . PROSITE PS00432; ACTINS_2; 1; . PROSITE PS01132; ACTINS_ACT_LIKE; 1; . World-2DPAGE Repository (search AC)