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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: P78371 World-2DPAGE Repository (0054):  P78371 P78371 General information about the entry View entry in simple text format Entry name TCPB_HUMAN Primary accession number P78371 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta;. Gene name Name=CCT2 Synonyms=99D8.1, CCTB Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 681: pI=6.02; Mw=57357   [identification data] %COV: SPOT 681: 55 [1]. SCORE: SPOT 681: 603 [1]. SEARCH ENGINE: SPOT 681: Mascot [1]. MAPPING (identification): SPOT 681: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot P78371; TCPB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TCPB_HUMAN Primary accession number P78371 Secondary accession number(s) A8K402 B5BTY7 B7Z243 B7Z7K4 B7ZAT2 Q14D36 Q6IAT3 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  October 1, 2014 (version 141) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta; Gene name Name=CCT2 Synonyms=99D8.1, CCTB Encoded on Name=CCT2; Synonyms=99D8.1, CCTB Keywords Acetylation; Alternative splicing; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF026293; AAC96012.1; -; mRNA EMBL AF026166; AAC98906.1; -; mRNA EMBL BT019966; AAV38769.1; -; mRNA EMBL AK290767; BAF83456.1; -; mRNA EMBL AK294307; BAH11729.1; -; mRNA EMBL AK302157; BAH13640.1; -; mRNA EMBL AK316397; BAH14768.1; -; mRNA EMBL AK316408; BAH14779.1; -; mRNA EMBL CR457071; CAG33352.1; -; mRNA EMBL AB451223; BAG70037.1; -; mRNA EMBL AB451346; BAG70160.1; -; mRNA EMBL AC018921; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471054; EAW97230.1; -; Genomic_DNA EMBL BC113514; AAI13515.1; -; mRNA EMBL BC113516; AAI13517.1; -; mRNA EMBL U91327; AAB67249.1; -; Genomic_DNA CCDS CCDS55843.1; -. [P78371-2]; . CCDS CCDS8991.1; -. [P78371-1]; . RefSeq NP_001185771.1; NM_001198842.1. [P78371-2]; . RefSeq NP_006422.1; NM_006431.2. [P78371-1]; . UniGene Hs.189772; -; . ProteinModelPortal P78371; -; . SMR P78371; 14-526; . BioGrid 115827; 106; . DIP DIP-38123N; -; . IntAct P78371; 52; . MINT MINT-8213815; -; . STRING 9606.ENSP00000299300; -; . PhosphoSite P78371; -; . DMDM 6094436; -; . OGP P78371; -; . REPRODUCTION-2DPAGE IPI00297779; -; . SWISS-2DPAGE P78371; -; . UCD-2DPAGE P78371; -; . MaxQB P78371; -; . PaxDb P78371; -; . PeptideAtlas P78371; -; . PRIDE P78371; -; . DNASU 10576; -; . Ensembl ENST00000299300; ENSP00000299300; ENSG00000166226. [P78371-1]; . Ensembl ENST00000543146; ENSP00000445471; ENSG00000166226. [P78371-2]; . GeneID 10576; -; . KEGG hsa:10576; -; . UCSC uc001svb.1; human. [P78371-1]; . CTD 10576; -; . GeneCards GC12P069979; -; . HGNC HGNC:1615; CCT2; . HPA CAB009850; -; . HPA HPA003197; -; . HPA HPA003198; -; . MIM 605139; gene; . neXtProt NX_P78371; -; . PharmGKB PA26179; -; . eggNOG COG0459; -; . HOGENOM HOG000226736; -; . HOVERGEN HBG001052; -; . InParanoid P78371; -; . KO K09494; -; . OMA ESGDNIR; -; . OrthoDB EOG7Q5HD3; -; . PhylomeDB P78371; -; . TreeFam TF105645; -; . Reactome REACT_16907; Association of TriC/CCT with target proteins during biosynthesis; . Reactome REACT_16936; Prefoldin mediated transfer of substrate to CCT/TriC; . Reactome REACT_16956; Formation of tubulin folding intermediates by CCT/TriC; . Reactome REACT_17050; Folding of actin by CCT/TriC; . ChiTaRS CCT2; human; . GeneWiki CCT2_(gene); -; . GenomeRNAi 10576; -; . NextBio 40141; -; . PRO PR:P78371; -; . ArrayExpress P78371; -; . Bgee P78371; -; . CleanEx HS_CCT2; -; . Genevestigator P78371; -; . GO GO:0044297; C:cell body; IEA:Ensembl; . GO GO:0005832; C:chaperonin-containing T-complex; IEA:Ensembl; . GO GO:0005829; C:cytosol; NAS:UniProtKB; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt; . GO GO:0005874; C:microtubule; IDA:UniProtKB; . GO GO:0002199; C:zona pellucida receptor complex; IEA:Ensembl; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0005515; F:protein binding; IPI:IntAct; . GO GO:0051082; F:unfolded protein binding; NAS:UniProtKB; . GO GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome; . GO GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl; . GO GO:0044267; P:cellular protein metabolic process; TAS:Reactome; . GO GO:0051131; P:chaperone-mediated protein complex assembly; IMP:MGI; . GO GO:0006457; P:protein folding; NAS:UniProtKB; . Gene3D 1.10.560.10; -; 2; . Gene3D 3.30.260.10; -; 2; . Gene3D 3.50.7.10; -; 1; . InterPro IPR012716; Chap_CCT_beta; . InterPro IPR017998; Chaperone_TCP-1; . InterPro IPR002194; Chaperonin_TCP-1_CS; . InterPro IPR002423; Cpn60/TCP-1; . InterPro IPR027409; GroEL-like_apical_dom; . InterPro IPR027413; GROEL-like_equatorial; . InterPro IPR027410; TCP-1-like_intermed; . PANTHER PTHR11353; PTHR11353; 1; . Pfam PF00118; Cpn60_TCP1; 1; . PRINTS PR00304; TCOMPLEXTCP1; . SUPFAM SSF48592; SSF48592; 2; . SUPFAM SSF52029; SSF52029; 1; . TIGRFAMs TIGR02341; chap_CCT_beta; 1; . PROSITE PS00750; TCP1_1; 1; . PROSITE PS00751; TCP1_2; 1; . PROSITE PS00995; TCP1_3; 1; . 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