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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: Q01105 World-2DPAGE Repository (0054):  Q01105 Q01105 General information about the entry View entry in simple text format Entry name SET_HUMAN Primary accession number Q01105 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Protein SET; AltName: Full=HLA-DR-associated protein II; AltName: Full=Inhibitor of granzyme A-activated DNase; Short=IGAAD; AltName: Full=PHAPII; AltName: Full=Phosphatase 2A inhibitor I2PP2A; Short=I-2PP2A; AltName: Full=Template-activating factor I; Short=TAF-I;. Gene name Name=SET Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 876: pI=4.22; Mw=33358   [identification data] %COV: SPOT 876: 34 [1]. SCORE: SPOT 876: 610 [1]. SEARCH ENGINE: SPOT 876: Mascot [1]. MAPPING (identification): SPOT 876: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot Q01105; SET_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SET_HUMAN Primary accession number Q01105 Secondary accession number(s) A5A5H4 A6NGV1 B4DUE2 Q15541 Q5VXV1 Q5VXV2 Q6FHZ5 Sequence was last modified on  April 13, 2004 (version 3) Annotations were last modified on  October 1, 2014 (version 154) Name and origin of the protein Description RecName: Full=Protein SET; AltName: Full=HLA-DR-associated protein II; AltName: Full=Inhibitor of granzyme A-activated DNase; Short=IGAAD; AltName: Full=PHAPII; AltName: Full=Phosphatase 2A inhibitor I2PP2A; Short=I-2PP2A; AltName: Full=Template-activating factor I; Short=TAF-I; Gene name Name=SET Encoded on Name=SET Keywords 3D-structure; Acetylation; Alternative splicing; Chaperone; Chromosomal rearrangement; Complete proteome; Cytoplasm; Direct protein sequencing; DNA-binding; Endoplasmic reticulum; Isopeptide bond; Methylation; Nucleus; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M93651; AAA60318.1; -; mRNA EMBL X75091; CAA52982.1; -; mRNA EMBL D45198; BAA08139.1; -; mRNA EMBL U51924; AAC50460.1; -; mRNA EMBL AY349172; AAQ79833.1; -; mRNA EMBL CR536543; CAG38780.1; -; mRNA EMBL CR542050; CAG46847.1; -; mRNA EMBL AK223556; BAD97276.1; -; mRNA EMBL AK300609; BAG62304.1; -; mRNA EMBL AL356481; CAH71410.1; -; Genomic_DNA EMBL AL359678; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC032749; AAH32749.1; -; mRNA EMBL EF534308; ABP96841.1; -; mRNA CCDS CCDS48037.1; -. [Q01105-1]; . CCDS CCDS59150.1; -. [Q01105-3]; . PIR A57984; A45018; . PIR I59377; I59377; . RefSeq NP_001116293.1; NM_001122821.1. [Q01105-1]; . RefSeq NP_001234929.1; NM_001248000.1; . RefSeq NP_001234930.1; NM_001248001.1. [Q01105-3]; . RefSeq NP_003002.2; NM_003011.3; . UniGene Hs.436687; -; . PDB 2E50; X-ray; 2.30 A; A/B/P/Q=38-238 PDBsum 2E50; -; . ProteinModelPortal Q01105; -; . SMR Q01105; 38-236; . BioGrid 112316; 105; . DIP DIP-33561N; -; . IntAct Q01105; 75; . MINT MINT-4990855; -; . STRING 9606.ENSP00000361777; -; . PhosphoSite Q01105; -; . DMDM 46397790; -; . MaxQB Q01105; -; . PaxDb Q01105; -; . PeptideAtlas Q01105; -; . PRIDE Q01105; -; . DNASU 6418; -; . Ensembl ENST00000372688; ENSP00000361773; ENSG00000119335. [Q01105-3]; . Ensembl ENST00000372692; ENSP00000361777; ENSG00000119335. [Q01105-1]; . GeneID 6418; -; . KEGG hsa:6418; -; . UCSC uc004bvt.4; human. [Q01105-1]; . UCSC uc004bvu.4; human. [Q01105-2]; . UCSC uc011mbj.2; human; . CTD 6418; -; . GeneCards GC09P131445; -; . HGNC HGNC:10760; SET; . HPA CAB005232; -; . MIM 600960; gene; . neXtProt NX_Q01105; -; . PharmGKB PA35678; -; . eggNOG NOG260846; -; . HOGENOM HOG000232096; -; . HOVERGEN HBG014779; -; . InParanoid Q01105; -; . KO K11290; -; . OMA TWFTDHA; -; . PhylomeDB Q01105; -; . TreeFam TF313386; -; . Reactome REACT_172744; Condensation of Prophase Chromosomes; . Reactome REACT_25218; HuR stabilizes mRNA; . ChiTaRS SET; human; . EvolutionaryTrace Q01105; -; . GeneWiki Protein_SET; -; . GenomeRNAi 6418; -; . NextBio 24926; -; . PRO PR:Q01105; -; . ArrayExpress Q01105; -; . Bgee Q01105; -; . CleanEx HS_SET; -; . Genevestigator Q01105; -; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IEA:UniProtKB-SubCell; . GO GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB; . GO GO:0043234; C:protein complex; IDA:UniProtKB; . GO GO:0003677; F:DNA binding; IEA:UniProtKB-KW; . GO GO:0042393; F:histone binding; TAS:UniProtKB; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0004864; F:protein phosphatase inhibitor activity; TAS:ProtInc; . GO GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:UniProtKB; . GO GO:0006260; P:DNA replication; TAS:ProtInc; . GO GO:0010467; P:gene expression; TAS:Reactome; . GO GO:0000278; P:mitotic cell cycle; TAS:Reactome; . GO GO:0016071; P:mRNA metabolic process; TAS:Reactome; . GO GO:0043086; P:negative regulation of catalytic activity; TAS:GOC; . GO GO:0035067; P:negative regulation of histone acetylation; TAS:UniProtKB; . GO GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI; . GO GO:0045892; P:negative regulation of transcription; DNA-templated; IDA:UniProtKB GO GO:0006913; P:nucleocytoplasmic transport; NAS:UniProtKB; . GO GO:0006334; P:nucleosome assembly; TAS:ProtInc; . GO GO:0006337; P:nucleosome disassembly; TAS:UniProtKB; . GO GO:0050790; P:regulation of catalytic activity; TAS:GOC; . GO GO:0016070; P:RNA metabolic process; TAS:Reactome; . InterPro IPR002164; NAP_family; . PANTHER PTHR11875; PTHR11875; 1; . Pfam PF00956; NAP; 1; . 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