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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: Q13263 World-2DPAGE Repository (0054):  Q13263 Q13263 General information about the entry View entry in simple text format Entry name TIF1B_HUMAN Primary accession number Q13263 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Transcription intermediary factor 1-beta; Short=TIF1-beta; AltName: Full=E3 SUMO-protein ligase TRIM28; EC=6.3.2.-; AltName: Full=KRAB-associated protein 1; Short=KAP-1; AltName: Full=KRAB-interacting protein 1; Short=KRIP-1; AltName: Full=Nuclear corepressor KAP-1; AltName: Full=RING finger protein 96; AltName: Full=Tripartite motif-containing protein 28;. Gene name Name=TRIM28 Synonyms=KAP1, RNF96, TIF1B Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 339: pI=5.52; Mw=88418   [identification data] %COV: SPOT 339: 32 [1]. SCORE: SPOT 339: 378 [1]. SEARCH ENGINE: SPOT 339: Mascot [1]. MAPPING (identification): SPOT 339: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot Q13263; TIF1B_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TIF1B_HUMAN Primary accession number Q13263 Secondary accession number(s) O00677 Q7Z632 Q93040 Q96IM1 Sequence was last modified on  January 23, 2007 (version 5) Annotations were last modified on  October 1, 2014 (version 179) Name and origin of the protein Description RecName: Full=Transcription intermediary factor 1-beta; Short=TIF1-beta; AltName: Full=E3 SUMO-protein ligase TRIM28; EC=6.3.2.-; AltName: Full=KRAB-associated protein 1; Short=KAP-1; AltName: Full=KRAB-interacting protein 1; Short=KRIP-1; AltName: Full=Nuclear corepressor KAP-1; AltName: Full=RING finger protein 96; AltName: Full=Tripartite motif-containing protein 28; Gene name Name=TRIM28 Synonyms=KAP1, RNF96, TIF1B Encoded on Name=TRIM28; Synonyms=KAP1, RNF96, TIF1B Keywords 3D-structure; Acetylation; Alternative splicing; Citrullination; Complete proteome; Direct protein sequencing; Isopeptide bond; Ligase; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U78773; AAB37341.1; -; mRNA EMBL X97548; CAA66150.1; -; mRNA EMBL U95040; AAB51517.1; -; mRNA EMBL BC004978; AAH04978.1; -; mRNA EMBL BC007390; AAH07390.2; -; mRNA EMBL BC052986; AAH52986.1; -; mRNA EMBL U31657; AAA74954.1; -; mRNA CCDS CCDS12985.1; -. [Q13263-1]; . PIR G01950; G01950; . RefSeq NP_005753.1; NM_005762.2. [Q13263-1]; . UniGene Hs.467408; -; . PDB 1FP0; NMR; -; A=619-679 PDB 2RO1; NMR; -; A=624-812 PDB 2YVR; X-ray; 1.80 A; A/B=201-250 PDBsum 1FP0; -; . PDBsum 2RO1; -; . PDBsum 2YVR; -; . ProteinModelPortal Q13263; -; . SMR Q13263; 62-128; 203-247; 624-812 BioGrid 115457; 181; . DIP DIP-30891N; -; . IntAct Q13263; 50; . MINT MINT-5001244; -; . STRING 9606.ENSP00000253024; -; . PhosphoSite Q13263; -; . DMDM 3183179; -; . MaxQB Q13263; -; . PaxDb Q13263; -; . PeptideAtlas Q13263; -; . PRIDE Q13263; -; . DNASU 10155; -; . Ensembl ENST00000253024; ENSP00000253024; ENSG00000130726. [Q13263-1]; . Ensembl ENST00000341753; ENSP00000342232; ENSG00000130726. [Q13263-2]; . GeneID 10155; -; . KEGG hsa:10155; -; . UCSC uc002qtg.1; human. [Q13263-1]; . UCSC uc010eut.1; human. [Q13263-2]; . CTD 10155; -; . GeneCards GC19P059055; -; . HGNC HGNC:16384; TRIM28; . HPA CAB010066; -; . MIM 601742; gene; . neXtProt NX_Q13263; -; . PharmGKB PA38131; -; . eggNOG NOG284491; -; . HOGENOM HOG000137674; -; . HOVERGEN HBG055353; -; . InParanoid Q13263; -; . KO K08882; -; . OMA ANQQKCE; -; . OrthoDB EOG790FZZ; -; . PhylomeDB Q13263; -; . TreeFam TF106455; -; . Reactome REACT_12627; Generic Transcription Pathway; . SignaLink Q13263; -; . UniPathway UPA00886; -; . EvolutionaryTrace Q13263; -; . GeneWiki TRIM28; -; . GenomeRNAi 10155; -; . NextBio 38440; -; . PMAP-CutDB Q13263; -; . PRO PR:Q13263; -; . ArrayExpress Q13263; -; . Bgee Q13263; -; . CleanEx HS_TRIM28; -; . Genevestigator Q13263; -; . GO GO:0005719; C:nuclear euchromatin; IEA:Ensembl; . GO GO:0005720; C:nuclear heterochromatin; IEA:Ensembl; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL; . GO GO:0003677; F:DNA binding; IDA:UniProtKB; . GO GO:0035851; F:Krueppel-associated box domain binding; IDA:UniProtKB; . GO GO:0016874; F:ligase activity; IEA:UniProtKB-KW; . GO GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0004672; F:protein kinase activity; IEA:Ensembl; . GO GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl; . GO GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl; . GO GO:0003713; F:transcription coactivator activity; IEA:Ensembl; . GO GO:0003714; F:transcription corepressor activity; IDA:UniProtKB; . GO GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB; . GO GO:0004842; F:ubiquitin-protein transferase activity; IDA:UniProtKB; . GO GO:0008270; F:zinc ion binding; IDA:UniProtKB; . GO GO:0060028; P:convergent extension involved in axis elongation; IEA:Ensembl; . GO GO:0006281; P:DNA repair; IDA:UniProtKB; . GO GO:0060669; P:embryonic placenta morphogenesis; IEA:Ensembl; . GO GO:0001837; P:epithelial to mesenchymal transition; ISS:HGNC; . GO GO:0010467; P:gene expression; TAS:Reactome; . GO GO:0045087; P:innate immune response; IDA:UniProt; . GO GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl; . GO GO:0045892; P:negative regulation of transcription; DNA-templated; IDA:UniProtKB GO GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt; . GO GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB; . GO GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:UniProtKB; . GO GO:0045893; P:positive regulation of transcription; DNA-templated; ISS:HGNC GO GO:0046777; P:protein autophosphorylation; IEA:Ensembl; . GO GO:0051259; P:protein oligomerization; IDA:UniProtKB; . GO GO:0016925; P:protein sumoylation; IDA:UniProtKB; . GO GO:0016567; P:protein ubiquitination; IDA:GOC; . GO GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome; . Gene3D 1.20.920.10; -; 1; . Gene3D 3.30.40.10; -; 2; . InterPro IPR003649; Bbox_C; . InterPro IPR001487; Bromodomain; . InterPro IPR019786; Zinc_finger_PHD-type_CS; . InterPro IPR000315; Znf_B-box; . InterPro IPR011011; Znf_FYVE_PHD; . InterPro IPR001965; Znf_PHD; . InterPro IPR019787; Znf_PHD-finger; . InterPro IPR001841; Znf_RING; . InterPro IPR013083; Znf_RING/FYVE/PHD; . Pfam PF00628; PHD; 1; . Pfam PF00643; zf-B_box; 2; . Pfam PF14634; zf-RING_5; 1; . SMART SM00502; BBC; 1; . SMART SM00336; BBOX; 2; . SMART SM00297; BROMO; 1; . SMART SM00249; PHD; 1; . SMART SM00184; RING; 2; . SUPFAM SSF57903; SSF57903; 1; . PROSITE PS50119; ZF_BBOX; 2; . PROSITE PS01359; ZF_PHD_1; 1; . PROSITE PS50016; ZF_PHD_2; 1; . PROSITE PS50089; ZF_RING_2; 1; . World-2DPAGE Repository (search AC)