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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: Q15366 World-2DPAGE Repository (0054):  Q15366 Q15366 General information about the entry View entry in simple text format Entry name PCBP2_HUMAN Primary accession number Q15366 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Poly(rC)-binding protein 2; AltName: Full=Alpha-CP2; AltName: Full=Heterogeneous nuclear ribonucleoprotein E2; Short=hnRNP E2;. Gene name Name=PCBP2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 826: pI=6.33; Mw=38580   [identification data] %COV: SPOT 826: 47 [1]. SCORE: SPOT 826: 351 [1]. SEARCH ENGINE: SPOT 826: Mascot [1]. MAPPING (identification): SPOT 826: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot Q15366; PCBP2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PCBP2_HUMAN Primary accession number Q15366 Secondary accession number(s) A8K7X6 F8VYL7 G3V0E8 I6L8F9 Q32Q82 Q59HD4 Q68Y55 Q6IPF4 Q6PKG5 Sequence was last modified on  November 1, 1996 (version 1) Annotations were last modified on  October 1, 2014 (version 145) Name and origin of the protein Description RecName: Full=Poly(rC)-binding protein 2; AltName: Full=Alpha-CP2; AltName: Full=Heterogeneous nuclear ribonucleoprotein E2; Short=hnRNP E2; Gene name Name=PCBP2 Encoded on Name=PCBP2 Keywords 3D-structure; Alternative splicing; Antiviral defense; Complete proteome; Cytoplasm; Direct protein sequencing; DNA-binding; Immunity; Innate immunity; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X78136; CAA55015.1; -; mRNA EMBL AB188306; BAD36897.1; -; mRNA EMBL AK292141; BAF84830.1; -; mRNA EMBL AB208825; BAD92062.1; ALT_INIT; mRNA EMBL AC023509; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC068889; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471054; EAW96706.1; -; Genomic_DNA EMBL CH471054; EAW96707.1; -; Genomic_DNA EMBL CH471054; EAW96709.1; -; Genomic_DNA EMBL CH471054; EAW96711.1; -; Genomic_DNA EMBL BC001155; AAH01155.1; -; mRNA EMBL BC071942; AAH71942.1; -; mRNA EMBL BC107688; AAI07689.1; -; mRNA CCDS CCDS44900.1; -. [Q15366-2]; . CCDS CCDS44901.1; -. [Q15366-1]; . CCDS CCDS44902.1; -. [Q15366-5]; . CCDS CCDS44903.1; -. [Q15366-4]; . CCDS CCDS44904.1; -. [Q15366-7]; . CCDS CCDS55830.1; -. [Q15366-6]; . CCDS CCDS8859.1; -. [Q15366-3]; . PIR S65679; S42471; . RefSeq NP_001092090.1; NM_001098620.2. [Q15366-4]; . RefSeq NP_001122383.1; NM_001128911.1. [Q15366-1]; . RefSeq NP_001122384.1; NM_001128912.1. [Q15366-6]; . RefSeq NP_001122385.1; NM_001128913.1. [Q15366-5]; . RefSeq NP_001122386.1; NM_001128914.1. [Q15366-7]; . RefSeq NP_005007.2; NM_005016.5. [Q15366-2]; . RefSeq NP_114366.1; NM_031989.4. [Q15366-3]; . UniGene Hs.546271; -; . PDB 2AXY; X-ray; 1.70 A; A/B/C/D=11-82 PDB 2JZX; NMR; -; A=11-169 PDB 2P2R; X-ray; 1.60 A; A=285-359 PDB 2PQU; X-ray; 2.12 A; A/B/C/D=11-82 PDB 2PY9; X-ray; 2.56 A; A/B/C/D=11-82 PDBsum 2AXY; -; . PDBsum 2JZX; -; . PDBsum 2P2R; -; . PDBsum 2PQU; -; . PDBsum 2PY9; -; . ProteinModelPortal Q15366; -; . SMR Q15366; 11-169; 286-358; . BioGrid 111127; 60; . DIP DIP-58934N; -; . IntAct Q15366; 34; . MINT MINT-96192; -; . STRING 9606.ENSP00000352438; -; . PhosphoSite Q15366; -; . DMDM 6707736; -; . MaxQB Q15366; -; . PaxDb Q15366; -; . PeptideAtlas Q15366; -; . PRIDE Q15366; -; . DNASU 5094; -; . Ensembl ENST00000359282; ENSP00000352228; ENSG00000197111. [Q15366-4]; . Ensembl ENST00000359462; ENSP00000352438; ENSG00000197111. [Q15366-2]; . Ensembl ENST00000437231; ENSP00000390304; ENSG00000197111. [Q15366-7]; . Ensembl ENST00000439930; ENSP00000408949; ENSG00000197111. [Q15366-1]; . Ensembl ENST00000447282; ENSP00000394116; ENSG00000197111. [Q15366-5]; . Ensembl ENST00000455667; ENSP00000388008; ENSG00000197111. [Q15366-7]; . Ensembl ENST00000546463; ENSP00000448762; ENSG00000197111. [Q15366-3]; . Ensembl ENST00000548933; ENSP00000449062; ENSG00000197111. [Q15366-5]; . Ensembl ENST00000552296; ENSP00000448927; ENSG00000197111. [Q15366-6]; . GeneID 5094; -; . KEGG hsa:5094; -; . UCSC uc001sdb.4; human. [Q15366-3]; . UCSC uc001sdc.4; human. [Q15366-2]; . UCSC uc001sdd.4; human. [Q15366-4]; . UCSC uc001sdf.4; human; . UCSC uc001sdi.4; human. [Q15366-5]; . UCSC uc001sdl.4; human. [Q15366-1]; . CTD 5094; -; . GeneCards GC12P053844; -; . HGNC HGNC:8648; PCBP2; . HPA HPA038356; -; . MIM 601210; gene; . neXtProt NX_Q15366; -; . PharmGKB PA32987; -; . eggNOG NOG315872; -; . HOGENOM HOG000182823; -; . HOVERGEN HBG053520; -; . InParanoid Q15366; -; . KO K13162; -; . OMA HACPESA; -; . OrthoDB EOG7P02J4; -; . PhylomeDB Q15366; -; . TreeFam TF318292; -; . Reactome REACT_125; Processing of Capped Intron-Containing Pre-mRNA; . Reactome REACT_25271; Negative regulators of RIG-I/MDA5 signaling; . Reactome REACT_467; mRNA Splicing - Major Pathway; . ChiTaRS PCBP2; human; . EvolutionaryTrace Q15366; -; . GeneWiki PCBP2; -; . GenomeRNAi 5094; -; . NextBio 19648; -; . PRO PR:Q15366; -; . ArrayExpress Q15366; -; . Bgee Q15366; -; . CleanEx HS_PCBP2; -; . Genevestigator Q15366; -; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular vesicular exosome; IDA:UniProt; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProt; . GO GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW; . GO GO:0003677; F:DNA binding; IEA:UniProtKB-KW; . GO GO:0019899; F:enzyme binding; IPI:UniProtKB; . GO GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB; . GO GO:0051607; P:defense response to virus; IEA:UniProtKB-KW; . GO GO:0010467; P:gene expression; TAS:Reactome; . GO GO:0045087; P:innate immune response; TAS:Reactome; . GO GO:0016071; P:mRNA metabolic process; NAS:UniProtKB; . GO GO:0000398; P:mRNA splicing; via spliceosome; TAS:Reactome GO GO:0050687; P:negative regulation of defense response to virus; IMP:UniProtKB; . GO GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome; . GO GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB; . GO GO:0008380; P:RNA splicing; TAS:Reactome; . Gene3D 3.30.1370.10; -; 3; . InterPro IPR004087; KH_dom; . InterPro IPR004088; KH_dom_type_1; . Pfam PF00013; KH_1; 3; . SMART SM00322; KH; 3; . SUPFAM SSF54791; SSF54791; 3; . PROSITE PS50084; KH_TYPE_1; 3; . World-2DPAGE Repository (search AC)