General information about the entry |
View entry in simple text format |
Entry name | MIC60_HUMAN |
Primary accession number | Q16891 |
integrated into World-2DPAGE Repository (0054) on | November 28, 2012 (release 1) |
2D Annotations were last modified on | November 28, 2012 (version 1) |
General Annotations were last modified on | October 23, 2014 (version 2) |
Name and origin of the protein |
Description | RecName: Full=MICOS complex subunit MIC60; AltName: Full=Cell proliferation-inducing gene 4/52 protein; AltName: Full=Mitochondrial inner membrane protein; AltName: Full=Mitofilin; AltName: Full=p87/89; Flags: Precursor;. |
Gene name | Name=IMMT Synonyms=HMP, MIC60, MINOS2 ORFNames=PIG4, PIG52
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Annotated species | Homo sapiens (Human) [TaxID: 9606] |
Taxonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
References |
[1] |
2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013)
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2D PAGE maps for identified proteins
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How to interpret a protein
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HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)
map experimental info
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HSAPIENS_CCRF-CEM_3-10
MAP LOCATIONS:
%COV: SPOT 445: 37 [1].
SCORE: SPOT 445: 438 [1].
SEARCH ENGINE: SPOT 445: Mascot [1].
MAPPING (identification):
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Copyright |
Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg |
Cross-references |
UniProtKB/Swiss-Prot | Q16891; MIC60_HUMAN. |
External data extracted from UniProtKB/Swiss-Prot |
Extracted from UniProtKB/Swiss-Prot, release: 0.0 |
Entry name | MIC60_HUMAN |
Primary accession number | Q16891 |
Secondary accession number(s) | B1H0U5 B2R5N6 Q14539 Q15092 Q68D41 Q69HW5 Q6IBL0 Q7Z3X1 Q8TAJ5 Q9P0V2 |
Sequence was last modified on | November 1, 1996 (version 1) |
Annotations were last modified on | October 1, 2014 (version 131) |
Name and origin of the protein |
Description | RecName: Full=MICOS complex subunit MIC60; AltName: Full=Cell proliferation-inducing gene 4/52 protein; AltName: Full=Mitochondrial inner membrane protein; AltName: Full=Mitofilin; AltName: Full=p87/89; Flags: Precursor; |
Gene name | Name=IMMT Synonyms=HMP, MIC60, MINOS2 ORFNames=PIG4, PIG52 |
Encoded on | Name=IMMT; Synonyms=HMP, MIC60, MINOS2; ORFNames=PIG4, PIG52 |
Keywords | Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Polymorphism; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix. |
Copyright |
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License |
Cross-references |
EMBL | D21091; BAA04653.1; -; mRNA |
EMBL | D21092; BAA04654.1; -; mRNA |
EMBL | D21093; BAA04655.1; -; mRNA |
EMBL | D21094; BAA04656.1; -; mRNA |
EMBL | L42572; AAA85336.1; -; mRNA |
EMBL | CR456793; CAG33074.1; -; mRNA |
EMBL | AK312251; BAG35183.1; -; mRNA |
EMBL | AY232292; AAP69987.1; -; mRNA |
EMBL | AY921637; AAX10024.1; -; mRNA |
EMBL | BX537369; CAD97612.1; -; mRNA |
EMBL | CR749590; CAH18389.1; ALT_TERM; mRNA |
EMBL | BC002412; AAH02412.1; -; mRNA |
EMBL | BC027458; AAH27458.1; -; mRNA |
EMBL | AF148646; AAF73126.1; -; mRNA |
CCDS | CCDS46355.1; -. [Q16891-1]; . |
CCDS | CCDS46356.1; -. [Q16891-4]; . |
CCDS | CCDS46357.1; -. [Q16891-2]; . |
RefSeq | NP_001093639.1; NM_001100169.1. [Q16891-4]; . |
RefSeq | NP_001093640.1; NM_001100170.1. [Q16891-2]; . |
RefSeq | NP_006830.2; NM_006839.2. [Q16891-1]; . |
RefSeq | XP_005264170.1; XM_005264113.1. [Q16891-3]; . |
UniGene | Hs.148559; -; . |
ProteinModelPortal | Q16891; -; . |
BioGrid | 116185; 88; . |
DIP | DIP-32517N; -; . |
IntAct | Q16891; 69; . |
MINT | MINT-1034498; -; . |
PhosphoSite | Q16891; -; . |
DMDM | 29427676; -; . |
REPRODUCTION-2DPAGE | IPI00554469; -; . |
REPRODUCTION-2DPAGE | Q16891; -; . |
MaxQB | Q16891; -; . |
PaxDb | Q16891; -; . |
PRIDE | Q16891; -; . |
DNASU | 10989; -; . |
Ensembl | ENST00000410111; ENSP00000387262; ENSG00000132305. [Q16891-1]; . |
Ensembl | ENST00000442664; ENSP00000407788; ENSG00000132305. [Q16891-4]; . |
Ensembl | ENST00000449247; ENSP00000396899; ENSG00000132305. [Q16891-2]; . |
GeneID | 10989; -; . |
KEGG | hsa:10989; -; . |
UCSC | uc002sqy.4; human. [Q16891-1]; . |
UCSC | uc002srb.4; human. [Q16891-2]; . |
CTD | 10989; -; . |
GeneCards | GC02M086282; -; . |
HGNC | HGNC:6047; IMMT; . |
HPA | CAB022439; -; . |
HPA | HPA036164; -; . |
HPA | HPA036165; -; . |
MIM | 600378; gene; . |
neXtProt | NX_Q16891; -; . |
PharmGKB | PA29858; -; . |
eggNOG | NOG307662; -; . |
HOVERGEN | HBG039233; -; . |
InParanoid | Q16891; -; . |
KO | K17785; -; . |
OMA | QKQKGDT; -; . |
PhylomeDB | Q16891; -; . |
TreeFam | TF312832; -; . |
ChiTaRS | IMMT; human; . |
GeneWiki | IMMT; -; . |
GenomeRNAi | 10989; -; . |
NextBio | 41751; -; . |
PRO | PR:Q16891; -; . |
ArrayExpress | Q16891; -; . |
Bgee | Q16891; -; . |
Genevestigator | Q16891; -; . |
GO | GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW; . |
GO | GO:0016020; C:membrane; IDA:UniProtKB; . |
GO | GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB; . |
GO | GO:0005739; C:mitochondrion; IDA:UniProt; . |
GO | GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . |
GO | GO:0005515; F:protein binding; IPI:UniProtKB; . |
GO | GO:0051560; P:mitochondrial calcium ion homeostasis; IEA:Ensembl; . |
GO | GO:0009409; P:response to cold; IEA:Ensembl; . |
InterPro | IPR019133; Mt-IM_prot_Mitofilin; . |
Pfam | PF09731; Mitofilin; 1; . |