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World-2DPAGE Repository
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World-2DPAGE Portal
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Searching in 'World-2DPAGE Repository [0022]' for entry
matching:
Q5BK81
World-2DPAGE Repository
(0022):
Q5BK81
Q5BK81
General information about the entry
View entry in simple text format
Entry name
PTGR2_RAT
Primary accession number
Q5BK81
integrated into World-2DPAGE Repository (0022) on
May 7, 2010 (release 1)
2D Annotations were last modified on
June 22, 2011 (version 2)
General Annotations were last modified on
November 24, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Prostaglandin reductase 2; Short=PRG-2; EC=1.3.1.48; AltName: Full=15-oxoprostaglandin 13-reductase; AltName: Full=Zinc-binding alcohol dehydrogenase domain-containing protein 1;.
Gene name
Name=Ptgr2
Synonyms=Zadh1
Annotated species
Rattus [TaxID:
10114
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1002/pmic.201000593
;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein
HCR_LCR_HEART
{HCR LCR Cardiac Map}
Rattus
Tissue: Heart
map experimental info
HCR_LCR_HEART
MAP LOCATIONS:
SPOT 9
:
pI=5.36; Mw=38511
[identification data]
IDENTIFICATION:
SPOT 9: SeqCov=22.2%. Peptides MS=7/20. Mascot PMF Score=48 [
1
].
PEPTIDE EVIDENCE:
SPOT 9: 25-VEEVSLPDTINEGQVR-40 (72) [
1
].
MAPPING (identification):
SPOT
9
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-Prot
Q5BK81; PTGR2_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_11
Entry name
PTGR2_RAT
Primary accession number
Q5BK81
Sequence was last modified on
July 22, 2008 (version 2)
Annotations were last modified on
November 16, 2011 (version 55)
Name and origin of the protein
Description
RecName: Full=Prostaglandin reductase 2; Short=PRG-2; EC=1.3.1.48; AltName: Full=15-oxoprostaglandin 13-reductase; AltName: Full=Zinc-binding alcohol dehydrogenase domain-containing protein 1;
Gene name
Name=Ptgr2
Synonyms=Zadh1
Encoded on
Name=Ptgr2; Synonyms=Zadh1
Keywords
Alternative splicing
;
Complete proteome
;
Cytoplasm
;
NADP
;
Oxidoreductase
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AABR03048578; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
AABR03050041; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
BC091173; AAH91173.1
; -; mRNA
IPI
IPI00365859; -
; .
IPI
IPI00900498; -
; .
RefSeq
NP_001015009.1; NM_001015009.1
; .
UniGene
Rn.203285; -
; .
HSSP
Q8VDQ1; 1VJ1
; .
ProteinModelPortal
Q5BK81; -
; .
SMR
Q5BK81; 1-350
; .
PRIDE
Q5BK81; -
; .
Ensembl
ENSRNOT00000058095; ENSRNOP00000054903
; ENSRNOG00000038166; .
Ensembl
ENSRNOT00000059073; ENSRNOP00000055851
; ENSRNOG00000038166; .
GeneID
299194; -
; .
KEGG
rno:299194; -
; .
UCSC
NM_001015009; rat
; .
CTD
145482; -
; .
RGD
131051; Zadh1
; .
eggNOG
roNOG16229; -
; .
GeneTree
ENSGT00390000009335; -
; .
HOVERGEN
HBG055024; -
; .
InParanoid
Q5BK81; -
; .
OMA
KERNITX; -
; .
OrthoDB
EOG4S4PGG; -
; .
NextBio
644957; -
; .
ArrayExpress
Q5BK81; -
; .
Genevestigator
Q5BK81; -
; .
GO
GO:0005737; C:cytoplasm
; IEA:UniProtKB-SubCell; .
GO
GO:0047522; F:15-oxoprostaglandin 13-oxidase activity
; ISS:UniProtKB; .
GO
GO:0008270; F:zinc ion binding
; IEA:InterPro; .
GO
GO:0006693; P:prostaglandin metabolic process
; ISS:UniProtKB; .
InterPro
IPR013149; ADH_C
; .
InterPro
IPR002085; ADH_SF_Zn-type
; .
InterPro
IPR011032; GroES-like
; .
InterPro
IPR016040; NAD(P)-bd_dom
; .
Gene3D
G3DSA:3.40.50.720; NAD(P)-bd
; 1; .
KO
K13949; -
; .
PANTHER
PTHR11695; ADH_Sf_Zn
; 1; .
Pfam
PF00107; ADH_zinc_N
; 1; .
SUPFAM
SSF50129; GroES_like
; 2; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server