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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0021]' for entry matching: Q61937 World-2DPAGE Repository (0021):  Q61937 Q61937 General information about the entry View entry in simple text format Entry name NPM_MOUSE Primary accession number Q61937 integrated into World-2DPAGE Repository (0021) on  June 9, 2010 (release 1) 2D Annotations were last modified on June 20, 2011 (version 2) General Annotations were last modified on  November 30, 2011 (version 2) Name and origin of the protein Description RecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin;. Gene name Name=Npm1 Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D-PAGE GEL CHARACTERIZATION De Cegli R., Romito A., Iacobacci S., Mao L., Lauria M., Fedele A.O., Klose J., Borel C., Descombes P., Antonarakis S.E., Di Bernardo D., Banfi S., Ballabio A., Cobellis G. ''A mouse Embryonic Stem Cell Bank for inducible overexpression of human Chromosome 21 genes'' Genome Biol 11(6):R64 (2010) 2D PAGE maps for identified proteins How to interpret a protein RUNX1_DAY7 {Mouse embryonic stem cells overexpressing Runx1, Day 7} Mus musculus (Mouse) Tissue: Embryonic stem cell   map experimental info   RUNX1_DAY7 MAP LOCATIONS: SPOT 2923: pI=4.62; Mw=32540   [identification data] EXPRESSION: SPOT 2923: Protein ratio 48h/0h=1.28 [1]. IDENTIFICATION: SPOT 2923: Mascot Protein score=242. SeqCov=10%. Peptides identified=6 [1]. MAPPING (identification): SPOT 2923: Tandem mass spectrometry [1]. Copyright Data from Dr. Lei Mao, Institute of Human Genetics, Charite Universitaetsmedizin Berlin, Germany Cross-references UniProtKB/Swiss-Prot Q61937; NPM_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name NPM_MOUSE Primary accession number Q61937 Sequence was last modified on  November 1, 1996 (version 1) Annotations were last modified on  November 16, 2011 (version 100) Name and origin of the protein Description RecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin; Gene name Name=Npm1 Encoded on Name=Npm1 Keywords Acetylation; ADP-ribosylation; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disulfide bond; DNA-binding; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; RNA-binding; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M33212; AAA39801.1; -; mRNA EMBL AK028253; BAC25844.1; -; mRNA EMBL BC054755; AAH54755.1; -; mRNA IPI IPI00127415; -; . PIR I52858; I52858; . RefSeq NP_032748.1; NM_008722.2; . UniGene Mm.485384; -; . ProteinModelPortal Q61937; -; . SMR Q61937; 15-118; 241-292; . IntAct Q61937; 2; . MINT MINT-270928; -; . STRING Q61937; -; . PhosphoSite Q61937; -; . PRIDE Q61937; -; . Ensembl ENSMUST00000075641; ENSMUSP00000075067; ENSMUSG00000057113; . GeneID 18148; -; . KEGG mmu:18148; -; . CTD 4869; -; . MGI MGI:106184; Npm1; . HOGENOM HBG278094; -; . HOVERGEN HBG001860; -; . InParanoid Q61937; -; . OMA NCFRTED; -; . OrthoDB EOG4W3SNZ; -; . PhylomeDB Q61937; -; . NextBio 293410; -; . ArrayExpress Q61937; -; . Bgee Q61937; -; . CleanEx MM_NPM1; -; . Genevestigator Q61937; -; . GermOnline ENSMUSG00000057113; Mus musculus; . GO GO:0005813; C:centrosome; ISS:UniProtKB; . GO GO:0005829; C:cytosol; IDA:MGI; . GO GO:0001652; C:granular component; IDA:MGI; . GO GO:0015934; C:large ribosomal subunit; IDA:MGI; . GO GO:0016607; C:nuclear speck; IDA:MGI; . GO GO:0015935; C:small ribosomal subunit; IDA:MGI; . GO GO:0003677; F:DNA binding; IEA:UniProtKB-KW; . GO GO:0051059; F:NF-kappaB binding; ISS:UniProtKB; . GO GO:0019843; F:rRNA binding; IDA:MGI; . GO GO:0051082; F:unfolded protein binding; ISS:UniProtKB; . GO GO:0007569; P:cell aging; ISS:UniProtKB; . GO GO:0016049; P:cell growth; IDA:MGI; . GO GO:0006884; P:cell volume homeostasis; IDA:MGI; . GO GO:0007098; P:centrosome cycle; ISS:UniProtKB; . GO GO:0006281; P:DNA repair; ISS:UniProtKB; . GO GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB; . GO GO:0048025; P:negative regulation of nuclear mRNA splicing; via spliceosome; IDA:MGI GO GO:0008284; P:positive regulation of cell proliferation; IDA:MGI; . GO GO:0031328; P:positive regulation of cellular biosynthetic process; IDA:MGI; . GO GO:0010825; P:positive regulation of centrosome duplication; IGI:MGI; . GO GO:0045860; P:positive regulation of protein kinase activity; IDA:MGI; . GO GO:0008104; P:protein localization; IMP:MGI; . GO GO:0043516; P:regulation of DNA damage response; signal transduction by p53 class mediator; IGI:MGI GO GO:0032071; P:regulation of endodeoxyribonuclease activity; ISS:UniProtKB; . GO GO:0060699; P:regulation of endoribonuclease activity; ISS:UniProtKB; . GO GO:0042273; P:ribosomal large subunit biogenesis; IMP:MGI; . GO GO:0000055; P:ribosomal large subunit export from nucleus; IMP:MGI; . GO GO:0042274; P:ribosomal small subunit biogenesis; IMP:MGI; . GO GO:0000056; P:ribosomal small subunit export from nucleus; IDA:MGI; . GO GO:0006407; P:rRNA export from nucleus; IDA:MGI; . InterPro IPR004301; Nucleoplasmin; . InterPro IPR024057; Nucleoplasmin_core; . Gene3D G3DSA:2.60.120.340; G3DSA:2.60.120.340; 1; . KO K11276; -; . PANTHER PTHR22747; Nucleoplasmin; 1; . Pfam PF03066; Nucleoplasmin; 1; . SUPFAM SSF69203; Nucleoplasmin; 1; . World-2DPAGE Repository (search AC)