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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0021]' for entry matching: Q8C0T5 World-2DPAGE Repository (0021):  Q8C0T5 Q8C0T5 General information about the entry View entry in simple text format Entry name SI1L1_MOUSE Primary accession number Q8C0T5 integrated into World-2DPAGE Repository (0021) on  June 9, 2010 (release 1) 2D Annotations were last modified on June 20, 2011 (version 2) General Annotations were last modified on  November 30, 2011 (version 2) Name and origin of the protein Description RecName: Full=Signal-induced proliferation-associated 1-like protein 1; Short=SIPA1-like protein 1;. Gene name Name=Sipa1l1 Synonyms=Kiaa0440 Annotated species Mus musculus (Mouse) [TaxID: 10090] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus. References [1]   2D-PAGE GEL CHARACTERIZATION De Cegli R., Romito A., Iacobacci S., Mao L., Lauria M., Fedele A.O., Klose J., Borel C., Descombes P., Antonarakis S.E., Di Bernardo D., Banfi S., Ballabio A., Cobellis G. ''A mouse Embryonic Stem Cell Bank for inducible overexpression of human Chromosome 21 genes'' Genome Biol 11(6):R64 (2010) 2D PAGE maps for identified proteins How to interpret a protein RUNX1_DAY7 {Mouse embryonic stem cells overexpressing Runx1, Day 7} Mus musculus (Mouse) Tissue: Embryonic stem cell   map experimental info   RUNX1_DAY7 MAP LOCATIONS: SPOT 2836: pI=8.65; Mw=19690   [identification data] EXPRESSION: SPOT 2836: Protein ratio 48h/0h=0.74. mRNA ratio 48h/0h=1.54 [1]. MAPPING (identification): SPOT 2836: Tandem mass spectrometry [1]. Copyright Data from Dr. Lei Mao, Institute of Human Genetics, Charite Universitaetsmedizin Berlin, Germany Cross-references UniProtKB/Swiss-Prot Q8C0T5; SI1L1_MOUSE. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name SI1L1_MOUSE Primary accession number Q8C0T5 Secondary accession number(s) Q6PDI8 Q80U02 Q8C026 Sequence was last modified on  July 19, 2004 (version 2) Annotations were last modified on  October 19, 2011 (version 82) Name and origin of the protein Description RecName: Full=Signal-induced proliferation-associated 1-like protein 1; Short=SIPA1-like protein 1; Gene name Name=Sipa1l1 Synonyms=Kiaa0440 Encoded on Name=Sipa1l1; Synonyms=Kiaa0440 Keywords Alternative splicing; Cell junction; Cell membrane; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTPase activation; Membrane; Phosphoprotein; Postsynaptic cell membrane; Reference proteome; Synapse; Synaptosome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AK029889; BAC26660.1; -; mRNA EMBL AK032493; BAC27896.1; -; mRNA EMBL BC058681; AAH58681.1; -; mRNA EMBL AK122284; BAC65566.1; -; mRNA IPI IPI00453688; -; . IPI IPI00453689; -; . RefSeq NP_001161455.1; NM_001167983.1; . RefSeq NP_766167.2; NM_172579.3; . UniGene Mm.261333; -; . ProteinModelPortal Q8C0T5; -; . SMR Q8C0T5; 479-824; 937-1027; . STRING Q8C0T5; -; . PhosphoSite Q8C0T5; -; . PRIDE Q8C0T5; -; . Ensembl ENSMUST00000053969; ENSMUSP00000061014; ENSMUSG00000042700; . Ensembl ENSMUST00000110321; ENSMUSP00000105950; ENSMUSG00000042700; . Ensembl ENSMUST00000166429; ENSMUSP00000131030; ENSMUSG00000042700; . GeneID 217692; -; . KEGG mmu:217692; -; . UCSC uc007ocu.2; mouse; . UCSC uc007ocw.2; mouse; . CTD 26037; -; . MGI MGI:2443679; Sipa1l1; . GeneTree ENSGT00550000074284; -; . HOGENOM HBG445166; -; . HOVERGEN HBG056135; -; . InParanoid Q8C0T5; -; . OMA GKMPPPE; -; . OrthoDB EOG4XGZZ6; -; . PhylomeDB Q8C0T5; -; . NextBio 375960; -; . ArrayExpress Q8C0T5; -; . Bgee Q8C0T5; -; . CleanEx MM_SIPA1L1; -; . Genevestigator Q8C0T5; -; . GermOnline ENSMUSG00000042700; Mus musculus; . GO GO:0030054; C:cell junction; IEA:UniProtKB-KW; . GO GO:0005737; C:cytoplasm; IEA:UniProtKB-KW; . GO GO:0005886; C:plasma membrane; IEA:UniProtKB-KW; . GO GO:0014069; C:postsynaptic density; ISS:UniProtKB; . GO GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW; . GO GO:0019717; C:synaptosome; ISS:UniProtKB; . GO GO:0046875; F:ephrin receptor binding; IPI:UniProtKB; . GO GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW; . GO GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB; . GO GO:0032861; P:activation of Rap GTPase activity; ISS:UniProtKB; . GO GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB; . GO GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB; . GO GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB; . InterPro IPR021818; DUF3401; . InterPro IPR001478; PDZ/DHR/GLGF; . InterPro IPR000331; Rap_GAP; . Pfam PF11881; DUF3401; 1; . Pfam PF02145; Rap_GAP; 1; . SMART SM00228; PDZ; 1; . SUPFAM SSF50156; PDZ; 1; . PROSITE PS50106; PDZ; 1; . PROSITE PS50085; RAPGAP; 1; . World-2DPAGE Repository (search AC)