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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0054]' for entry matching: Q8N684 World-2DPAGE Repository (0054):  Q8N684 Q8N684 General information about the entry View entry in simple text format Entry name CPSF7_HUMAN Primary accession number Q8N684 integrated into World-2DPAGE Repository (0054) on  November 28, 2012 (release 1) 2D Annotations were last modified on November 28, 2012 (version 1) General Annotations were last modified on  October 23, 2014 (version 2) Name and origin of the protein Description RecName: Full=Cleavage and polyadenylation specificity factor subunit 7; AltName: Full=Cleavage and polyadenylation specificity factor 59 kDa subunit; Short=CFIm59; Short=CPSF 59 kDa subunit; AltName: Full=Pre-mRNA cleavage factor Im 59 kDa subunit;. Gene name Name=CPSF7 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION DOI=10.1074/mcp.M112.022947; Vernocchi S., Battello N., Schmitz S., Revets D., Billing A.M., Turner J.D., Muller C.P. ''Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid-effects'' Molecular & Cellular Proteomics 12(7):1764-1779 (2013) 2D PAGE maps for identified proteins How to interpret a protein HSAPIENS_CCRF-CEM_3-10 {CCRF-CEM cells stimulated with Cort-BSA (internal standard)} Homo sapiens (Human)   map experimental info   HSAPIENS_CCRF-CEM_3-10 MAP LOCATIONS: SPOT 177805: pI=7.82; Mw=52050   [identification data] %COV: SPOT 177805: 26 [1]. SCORE: SPOT 177805: 169 [1]. SEARCH ENGINE: SPOT 177805: Mascot [1]. MAPPING (identification): SPOT 177805: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Claude P. Muller, Centre de Recherche Public de la Sante / National Public Health Laboratory, Luxembourg Cross-references UniProtKB/Swiss-Prot Q8N684; CPSF7_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CPSF7_HUMAN Primary accession number Q8N684 Secondary accession number(s) B3KU04 C9K0Q4 Q7Z3H9 Q9H025 Q9H9V1 Sequence was last modified on  October 1, 2002 (version 1) Annotations were last modified on  October 1, 2014 (version 117) Name and origin of the protein Description RecName: Full=Cleavage and polyadenylation specificity factor subunit 7; AltName: Full=Cleavage and polyadenylation specificity factor 59 kDa subunit; Short=CFIm59; Short=CPSF 59 kDa subunit; AltName: Full=Pre-mRNA cleavage factor Im 59 kDa subunit; Gene name Name=CPSF7 Encoded on Name=CPSF7 Keywords 3D-structure; Alternative splicing; Complete proteome; mRNA processing; Nucleus; Phosphoprotein; Reference proteome; RNA-binding. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AJ275970; CAC81661.1; -; mRNA EMBL AK022591; BAB14118.1; ALT_INIT; mRNA EMBL AK096343; BAG53266.1; -; mRNA EMBL AL512759; CAC21678.1; -; mRNA EMBL BX537888; CAD97884.1; ALT_INIT; mRNA EMBL AP003108; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC018135; AAH18135.1; ALT_INIT; mRNA CCDS CCDS44619.1; -. [Q8N684-1]; . CCDS CCDS44620.1; -. [Q8N684-2]; . CCDS CCDS8006.2; -. [Q8N684-3]; . RefSeq NP_001129512.1; NM_001136040.2. [Q8N684-1]; . RefSeq NP_001136037.1; NM_001142565.1. [Q8N684-2]; . RefSeq NP_079087.3; NM_024811.3. [Q8N684-3]; . RefSeq XP_005274356.1; XM_005274299.2. [Q8N684-1]; . RefSeq XP_006718753.1; XM_006718690.1. [Q8N684-3]; . RefSeq XP_006718754.1; XM_006718691.1. [Q8N684-3]; . UniGene Hs.718984; -; . PDB 3N9U; X-ray; 1.92 A; C/I=50-182 PDBsum 3N9U; -; . ProteinModelPortal Q8N684; -; . SMR Q8N684; 82-177; . BioGrid 122957; 42; . IntAct Q8N684; 17; . MINT MINT-1469392; -; . STRING 9606.ENSP00000345412; -; . PhosphoSite Q8N684; -; . DMDM 74759932; -; . MaxQB Q8N684; -; . PaxDb Q8N684; -; . PRIDE Q8N684; -; . DNASU 79869; -; . Ensembl ENST00000340437; ENSP00000345412; ENSG00000149532. [Q8N684-3]; . Ensembl ENST00000394888; ENSP00000378352; ENSG00000149532. [Q8N684-1]; . Ensembl ENST00000439958; ENSP00000397203; ENSG00000149532. [Q8N684-2]; . Ensembl ENST00000448745; ENSP00000407394; ENSG00000149532. [Q8N684-2]; . GeneID 79869; -; . KEGG hsa:79869; -; . UCSC uc001nrp.3; human. [Q8N684-3]; . UCSC uc001nrq.3; human. [Q8N684-1]; . UCSC uc001nrr.3; human. [Q8N684-2]; . CTD 79869; -; . GeneCards GC11M061170; -; . HGNC HGNC:30098; CPSF7; . HPA HPA041094; -; . neXtProt NX_Q8N684; -; . PharmGKB PA165543380; -; . eggNOG NOG313287; -; . HOGENOM HOG000111137; -; . HOVERGEN HBG056699; -; . InParanoid Q8N684; -; . KO K14398; -; . OMA RRGPFEG; -; . OrthoDB EOG74TX09; -; . PhylomeDB Q8N684; -; . TreeFam TF316430; -; . Reactome REACT_1096; Processing of Intronless Pre-mRNAs; . Reactome REACT_1849; mRNA 3'-end processing; . Reactome REACT_467; mRNA Splicing - Major Pathway; . ChiTaRS CPSF7; human; . EvolutionaryTrace Q8N684; -; . GeneWiki FLJ12529; -; . GenomeRNAi 79869; -; . NextBio 69628; -; . PMAP-CutDB Q8N684; -; . PRO PR:Q8N684; -; . ArrayExpress Q8N684; -; . Bgee Q8N684; -; . Genevestigator Q8N684; -; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005849; C:mRNA cleavage factor complex; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0000166; F:nucleotide binding; IEA:InterPro; . GO GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0010467; P:gene expression; TAS:Reactome; . GO GO:0031124; P:mRNA 3'-end processing; TAS:Reactome; . GO GO:0000398; P:mRNA splicing; via spliceosome; TAS:Reactome GO GO:0051262; P:protein tetramerization; IDA:UniProtKB; . GO GO:0008380; P:RNA splicing; TAS:Reactome; . GO GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome; . GO GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome; . Gene3D 3.30.70.330; -; 1; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . Pfam PF00076; RRM_1; 1; . SMART SM00360; RRM; 1; . PROSITE PS50102; RRM; 1; . World-2DPAGE Repository (search AC)