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Searching in 'World-2DPAGE Repository [0030]' for entry matching: Q921F2

World-2DPAGE Repository (0030):  Q921F2


General information about the entry
View entry in simple text format
Primary accession numberQ921F2
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=TAR DNA-binding protein 43; Short=TDP-43;.
Gene nameName=Tardbp
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
  map experimental info

pI=6.11; Mw=53470  [identification data]
pI=6.38; Mw=53248  [identification data]

IDENTIFICATION: SPOT 1280: Mascot protein score=61. Number of peptides=2 [1]
SPOT 1285: Mascot protein score=115. Number of peptides=5 [1].
MAPPING (identification):
SPOT 1280: Tandem mass spectrometry [1];
SPOT 1285: Tandem mass spectrometry [1].

Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
UniProtKB/Swiss-ProtQ921F2; TADBP_MOUSE.
World-2DPAGE RepositoryQ921F2; TADBP_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Primary accession numberQ921F2
Secondary accession number(s) Q3U591 Q3V0E7
Sequence was last modified on December 1, 2001 (version 1)
Annotations were last modified on October 19, 2011 (version 88)
Name and origin of the protein
DescriptionRecName: Full=TAR DNA-binding protein 43; Short=TDP-43;
Gene nameName=Tardbp
Encoded onName=Tardbp; Synonyms=Tdp43
Keywords3D-structure; Complete proteome; Direct protein sequencing; DNA-binding; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Repressor; RNA-binding; Transcription; Transcription regulation; Ubl conjugation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAK133207; BAE21557.1; -; mRNA
EMBLAK153803; BAE32189.1; -; mRNA
EMBLBC012873; AAH12873.1; -; mRNA
EMBLBC025544; AAH25544.1; -; mRNA
EMBLBC027772; AAH27772.1; -; mRNA
EMBLBC031126; AAH31126.1; -; mRNA
EMBLBC033475; AAH33475.1; -; mRNA
IPIIPI00121758; -; .
RefSeqNP_663531.1; NM_145556.4; .
UniGeneMm.22453; -; .
UniGeneMm.378962; -; .
PDB3D2W; X-ray; 1.65 A; A=192-265
PDBsum3D2W; -; .
ProteinModelPortalQ921F2; -; .
SMRQ921F2; 90-264; .
STRINGQ921F2; -; .
PhosphoSiteQ921F2; -; .
PRIDEQ921F2; -; .
EnsemblENSMUST00000084125; ENSMUSP00000081142; ENSMUSG00000041459; .
GeneID230908; -; .
KEGGmmu:230908; -; .
CTD23435; -; .
MGIMGI:2387629; Tardbp; .
GeneTreeENSGT00570000079202; -; .
HOGENOMHBG379398; -; .
HOVERGENHBG058671; -; .
InParanoidQ921F2; -; .
PhylomeDBQ921F2; -; .
NextBio380280; -; .
ArrayExpressQ921F2; -; .
BgeeQ921F2; -; .
CleanExMM_TARDBP; -; .
GenevestigatorQ921F2; -; .
GermOnlineENSMUSG00000041459; Mus musculus; .
GOGO:0005634; C:nucleus; IEA:UniProtKB-SubCell; .
GOGO:0000166; F:nucleotide binding; IEA:InterPro; .
GOGO:0006397; P:mRNA processing; IEA:UniProtKB-KW; .
GOGO:0006355; P:regulation of transcription; DNA-dependent; IEA:UniProtKB-KW
GOGO:0008380; P:RNA splicing; IEA:UniProtKB-KW; .
GOGO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW
InterProIPR012677; Nucleotide-bd_a/b_plait; .
InterProIPR000504; RRM_dom; .
Gene3DG3DSA:; a_b_plait_nuc_bd; 2; .
PfamPF00076; RRM_1; 2; .
SMARTSM00360; RRM; 2; .
PROSITEPS50102; RRM; 2; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server