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Searching in 'World-2DPAGE Repository [0021]' for entry matching: SERPH_MOUSE




World-2DPAGE Repository (0021):  SERPH_MOUSE


SERPH_MOUSE


General information about the entry
View entry in simple text format
Entry nameSERPH_MOUSE
Primary accession numberP19324
integrated into World-2DPAGE Repository (0021) on June 9, 2010 (release 1)
2D Annotations were last modified onJune 20, 2011 (version 2)
General Annotations were last modified on November 30, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Serpin H1; AltName: Full=47 kDa heat shock protein; AltName: Full=Collagen-binding protein; Short=Colligin; AltName: Full=Serine protease inhibitor J6; Flags: Precursor;.
Gene nameName=Serpinh1
Synonyms=Cbp1, Hsp47
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
De Cegli R., Romito A., Iacobacci S., Mao L., Lauria M., Fedele A.O., Klose J., Borel C., Descombes P., Antonarakis S.E., Di Bernardo D., Banfi S., Ballabio A., Cobellis G.
''A mouse Embryonic Stem Cell Bank for inducible overexpression of human Chromosome 21 genes''
Genome Biol 11(6):R64 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RUNX1_DAY7 {Mouse embryonic stem cells overexpressing Runx1, Day 7}
Mus musculus (Mouse)
Tissue: Embryonic stem cell
RUNX1_DAY7
  map experimental info
 
RUNX1_DAY7

MAP LOCATIONS:
pI=8.90; Mw=46560  [identification data]

EXPRESSION:
SPOT 645: Protein ratio 48h/0h=1.44. mRNA ratio 48h/0h=1.36 [1].

IDENTIFICATION: SPOT 645: Mascot Protein score=631. SeqCov=8%. Peptides identified=43 [1].
MAPPING (identification):
SPOT 645: Tandem mass spectrometry [1].

Copyright
Data from Dr. Lei Mao, Institute of Human Genetics, Charite Universitaetsmedizin Berlin, Germany
Cross-references
UniProtKB/Swiss-ProtP19324; SERPH_MOUSE.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameSERPH_MOUSE
Primary accession numberP19324
Secondary accession number(s) Q5U4D0
Sequence was last modified on July 27, 2011 (version 3)
Annotations were last modified on November 16, 2011 (version 108)
Name and origin of the protein
DescriptionRecName: Full=Serpin H1; AltName: Full=47 kDa heat shock protein; AltName: Full=Collagen-binding protein; Short=Colligin; AltName: Full=Serine protease inhibitor J6; Flags: Precursor;
Gene nameName=Serpinh1
Synonyms=Cbp1, Hsp47
Encoded onName=Serpinh1; Synonyms=Cbp1, Hsp47
KeywordsChaperone; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Glycoprotein; Reference proteome; Signal; Stress response.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX60676; CAA43091.1; -; mRNA
EMBLJ05609; AAA03200.1; ALT_SEQ; mRNA
EMBLD12907; BAA02298.1; -; Genomic_DNA
EMBLAK029080; BAC26283.1; -; mRNA
EMBLAK031457; BAC27413.1; -; mRNA
EMBLAK077660; BAC36935.1; -; mRNA
EMBLAK077937; BAC37075.1; -; mRNA
EMBLAK086519; BAC39683.1; -; mRNA
EMBLAK086523; BAC39684.1; -; mRNA
EMBLAK089993; BAC41032.1; -; mRNA
EMBLAK090103; BAC41093.1; -; mRNA
EMBLAK159998; BAE35546.1; -; mRNA
EMBLAK168442; BAE40347.1; -; mRNA
EMBLAK168870; BAE40689.1; -; mRNA
EMBLAC158748; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLBC085143; AAH85143.1; -; mRNA
IPIIPI00114733; -; .
PIRS23453; A42843; .
RefSeqNP_001104513.1; NM_001111043.1; .
RefSeqNP_001104514.1; NM_001111044.1; .
RefSeqNP_033955.2; NM_009825.2; .
UniGeneMm.22708; -; .
ProteinModelPortalP19324; -; .
SMRP19324; 39-409; .
STRINGP19324; -; .
MEROPSI04.035; -; .
PhosphoSiteP19324; -; .
REPRODUCTION-2DPAGEIPI00114733; -; .
PRIDEP19324; -; .
EnsemblENSMUST00000094154; ENSMUSP00000091706; ENSMUSG00000070436; .
EnsemblENSMUST00000169437; ENSMUSP00000126390; ENSMUSG00000070436; .
GeneID12406; -; .
KEGGmmu:12406; -; .
CTD871; -; .
MGIMGI:88283; Serpinh1; .
eggNOGmaNOG10784; -; .
HOGENOMHBG278637; -; .
HOVERGENHBG104930; -; .
InParanoidP19324; -; .
OrthoDBEOG43FGX2; -; .
NextBio281182; -; .
ArrayExpressP19324; -; .
BgeeP19324; -; .
GenevestigatorP19324; -; .
GermOnlineENSMUSG00000070436; Mus musculus; .
GOGO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell; .
GOGO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome; .
GOGO:0051082; F:unfolded protein binding; IDA:MGI; .
GOGO:0032964; P:collagen biosynthetic process; IMP:MGI; .
GOGO:0030199; P:collagen fibril organization; IMP:MGI; .
GOGO:0051604; P:protein maturation; IMP:MGI; .
GOGO:0030162; P:regulation of proteolysis; IBA:RefGenome; .
GOGO:0006950; P:response to stress; IEA:UniProtKB-KW; .
InterProIPR000215; Protease_inhib_I4_serpin; .
InterProIPR023795; Protease_inhib_I4_serpin_CS; .
InterProIPR023796; Sepin_dom; .
KOK09501; -; .
PANTHERPTHR11461; Prot_inh_serpin; 1; .
PfamPF00079; Serpin; 1; .
SMARTSM00093; SERPIN; 1; .
SUPFAMSSF56574; Prot_inh_serpin; 1; .
PROSITEPS00014; ER_TARGET; 1; .
PROSITEPS00284; SERPIN; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server