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Searching in 'World-2DPAGE Repository [0019]' for entry matching: SYN1_RAT

World-2DPAGE Repository (0019):  SYN1_RAT


General information about the entry
View entry in simple text format
Entry nameSYN1_RAT
Primary accession numberP09951
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Synapsin-1; AltName: Full=Synapsin I;.
Gene nameName=Syn1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
  map experimental info

pI=9.84; Mw=70037  [identification data]
pI=9.84; Mw=70037  [identification data]
pI=9.84; Mw=70037  [identification data]
pI=9.84; Mw=70037  [identification data]

IDENTIFICATION: SPOT 260: Peptides number=4. SeqCov=8.5%. MOWSE score=2.44E+3 [1]
SPOT 285: Peptides number=12. SeqCov=24.9%. MOWSE score=2.43E+10 [1]; SPOT 288: Peptides number=9. SeqCov=18.8%. MOWSE score=2.25E+8 [1]; SPOT 1141: Peptides number=7. SeqCov=15.2%. MOWSE score=3.08E+5 [1].
MAPPING (identification):
SPOT 260: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 285: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 288: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1141: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Willard Freeman, Penn State College of Medicine, USA
UniProtKB/Swiss-ProtP09951; SYN1_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameSYN1_RAT
Primary accession numberP09951
Secondary accession number(s) Q9WUX7
Sequence was last modified on May 30, 2000 (version 3)
Annotations were last modified on September 21, 2011 (version 109)
Name and origin of the protein
DescriptionRecName: Full=Synapsin-1; AltName: Full=Synapsin I;
Gene nameName=Syn1
Encoded onName=Syn1
Keywords3D-structure; Actin-binding; Alternative splicing; Cell junction; Complete proteome; Direct protein sequencing; Glycoprotein; Golgi apparatus; Phosphoprotein; Reference proteome; Repeat; Synapse.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLM27812; AAA42145.1; -; mRNA
EMBLM27924; AAA42148.1; -; mRNA
EMBLX04655; CAA28353.1; ALT_SEQ; mRNA
IPIIPI00191335; -; .
IPIIPI00231023; -; .
PIRA25704; A25704; .
PIRA30411; A30411; .
RefSeqNP_001104252.1; NM_001110782.1; .
RefSeqNP_062006.1; NM_019133.1; .
UniGeneRn.9923; -; .
PDB1PK8; X-ray; 2.10 A; A/B/C/D/E/F/G/H=2-421
PDB1PX2; X-ray; 2.23 A; A/B=2-421
PDBsum1PK8; -; .
PDBsum1PX2; -; .
ProteinModelPortalP09951; -; .
SMRP09951; 112-417; .
IntActP09951; 1; .
MINTMINT-139278; -; .
STRINGP09951; -; .
PhosphoSiteP09951; -; .
PRIDEP09951; -; .
GeneID24949; -; .
KEGGrno:24949; -; .
NMPDRfig|10116.3.peg.30766; -; .
CTD6853; -; .
RGD3797; Syn1; .
eggNOGmaNOG18102; -; .
GeneTreeENSGT00530000063319; -; .
HOVERGENHBG016354; -; .
InParanoidP09951; -; .
OrthoDBEOG4KPTB4; -; .
NextBio604961; -; .
ArrayExpressP09951; -; .
GenevestigatorP09951; -; .
GermOnlineENSRNOG00000010365; Rattus norvegicus; .
GOGO:0030054; C:cell junction; IEA:UniProtKB-KW; .
GOGO:0030425; C:dendrite; IDA:BHF-UCL; .
GOGO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0003779; F:actin binding; IEA:UniProtKB-KW; .
GOGO:0005524; F:ATP binding; IEA:InterPro; .
GOGO:0016874; F:ligase activity; IEA:InterPro; .
GOGO:0007269; P:neurotransmitter secretion; TAS:RGD; .
InterProIPR013815; ATP_grasp_subdomain_1; .
InterProIPR013816; ATP_grasp_subdomain_2; .
InterProIPR013817; Pre-ATP_grasp; .
InterProIPR016185; PreATP-grasp-like; .
InterProIPR001359; Synapsin; .
InterProIPR020898; Synapsin_ATP-bd_dom; .
InterProIPR019735; Synapsin_CS; .
InterProIPR019736; Synapsin_P_site; .
InterProIPR020897; Synapsin_pre-ATP-grasp_dom; .
Gene3DG3DSA:3.30.1490.20; ATP_grasp_subdomain_1; 1; .
Gene3DG3DSA:3.30.470.20; ATP_grasp_subdomain_2; 2; .
Gene3DG3DSA:; Pre-ATP_grasp; 1; .
PfamPF02078; Synapsin; 1; .
PfamPF02750; Synapsin_C; 1; .
PfamPF10581; Synapsin_N; 1; .
SUPFAMSSF52440; PreATP-grasp-like; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server